Research Topics | Daniel G MacArthurSummaryAffiliation: Wellcome Trust Genome Campus Country: UK Publications
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Publications
Biology of Genomes: making sense of sequenceDaniel G MacArthur
Human Evolution, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Genome Med 1:61. 2009..ABSTRACT : A report on the Biology of Genomes meeting held at Cold Spring Harbor Laboratory, NY, USA, 5-9 May 2009...
Loss-of-function variants in the genomes of healthy humansDaniel G MacArthur
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Hum Mol Genet 19:R125-30. 2010....
Human Y chromosome base-substitution mutation rate measured by direct sequencing in a deep-rooting pedigreeYali Xue
The Wellcome Trust Sanger Institute, Hinxton, Cambs CB10 1SA, UK
Curr Biol 19:1453-7. 2009..0 x 10(-8)), consistent with estimates of 2.3 x 10(-8)-6.3 x 10(-8) mutations/nucleotide/generation for the same Y-chromosomal region from published human-chimpanzee comparisons depending on the generation and split times assumed...
Dindel: accurate indel calls from short-read dataCornelis A Albers
Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1HH, United Kingdom
Genome Res 21:961-73. 2011..The algorithm is implemented in the program Dindel, which has been used in the 1000 Genomes Project call sets...
A map of human genome variation from population-scale sequencingRichard M Durbin
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK
Nature 467:1061-73. 2010..These methods and public data will support the next phase of human genetic research...
Origins and functional impact of copy number variation in the human genomeDonald F Conrad
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA UK
Nature 464:704-12. 2010....
The promise and reality of personal genomicsBryndis Yngvadottir
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
Genome Biol 10:237. 2009..The publication of the highest-quality and best-annotated personal genome yet tells us much about sequencing technology, something about genetic ancestry, but still little of medical relevance...
