Research Topics
Species | W Hamish B WallaceSummaryCountry: UK Publications
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Publications
Oncofertility and preservation of reproductive capacity in children and young adultsW Hamish B Wallace
Department of Pediatric Haematology Oncology, Royal Hospital for Sick Children, Edinburgh, Scotland, United Kingdom
Cancer 117:2301-10. 2011..For prepubertal girls, ovarian tissue cryopreservation should be considered if the risk of premature menopause is high, but for the prepubertal boy there are no established techniques in current practice...
Human ovarian reserve from conception to the menopauseW Hamish B Wallace
Department of Reproductive and Developmental Sciences, Division of Child Life and Health, University of Edinburgh, Edinburgh, United Kingdom
PLoS ONE 5:e8772. 2010..An increased understanding of the dynamics of human ovarian reserve will provide a more scientific basis for fertility counselling for both healthy women and those who have survived gonadotoxic cancer treatments...
Male fertility following childhood cancer: current concepts and future therapiesMark F H Brougham
Royal Hospital for Sick Children, 17 Millerfield Place, Edinburgh, EH9 1LW, UK
Asian J Androl 5:325-37. 2003....
Do doctors discuss fertility issues before they treat young patients with cancer?Richard A Anderson
Division of Developmental and Reproductive Science, University of Edinburgh, Edinburgh, UK
Hum Reprod 23:2246-51. 2008..We have assessed UK practice relating to information provision about the effects of cancer treatment on fertility and options for fertility preservation...
Physiological versus standard sex steroid replacement in young women with premature ovarian failure: effects on bone mass acquisition and turnoverPatricia M Crofton
Department of Paediatric Biochemistry, The Royal Hospital for Sick Children, Edinburgh, Scotland, UK
Clin Endocrinol (Oxf) 73:707-14. 2010..The aim of this exploratory study was to establish whether we could improve skeletal health with a physiological regimen of SSR in young women with premature ovarian failure (POF)...
Fertility preservation for young patients with cancer: who is at risk and what can be offered?W Hamish B Wallace
Department of Child Life and Health, Division of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, UK
Lancet Oncol 6:209-18. 2005....
Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancerRobert J Johnston
Royal Hospital for Sick Children, Edinburgh, Scotland, United Kingdom
Pediatr Blood Cancer 53:296-302. 2009..We discuss the physiology of normal ovarian function, the effects of cancer treatments on ovarian function and the techniques for evaluation of ovarian reserve in survivors of childhood cancer...
Late reproductive sequelae following treatment of childhood cancer and options for fertility preservationAngela B Thomson
Department of Haematology/Oncology, Royal Hospital for Sick Children, 17 Millerfield Place, Edinburgh, EH9 1LW, UK
Best Pract Res Clin Endocrinol Metab 16:311-34. 2002..In this chapter we consider the late reproductive sequelae following treatment for childhood cancer and options for fertility preservation...
Cardiovascular effects of physiological and standard sex steroid replacement regimens in premature ovarian failureJeremy P Langrish
Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, EH16 4SA United Kingdom
Hypertension 53:805-11. 2009..These findings have major implications for the future cardiovascular health of young women who require long-term sex steroid replacement therapy...
A validated model of serum anti-müllerian hormone from conception to menopauseThomas W Kelsey
School of Computer Science, University of St Andrews, St Andrews, Scotland, United Kingdom
PLoS ONE 6:e22024. 2011..e. the ovarian reserve, and be of value in predicting reproductive lifespan. A full description of AMH production up to the menopause has not been previously reported...
Bone Turnover and Growth during and after Chemotherapy in Children with Solid TumorsLouise F Bath
Section of Child Life and Health, Department of Reproductive and Developmental Sciences, 20 Sylvan Place, Edinburgh EH9 IUW, Scotland
Pediatr Res 55:224-30. 2004..BALP remained suppressed throughout treatment (p < 0.001). Intense courses of treatment for solid tumors have a direct suppressive effect on bone turnover, with an imbalance between collagen synthesis and degradation...
Semen quality and spermatozoal DNA integrity in survivors of childhood cancer: a case-control studyAngela B Thomson
Section of Child Life and Health, Department of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, UK
Lancet 360:361-7. 2002..However, the sperm produced seems to carry as much healthy DNA as those produced by the healthy population, suggesting that assisted conception can be considered as a treatment option for these men...
Radiation damage to the uterus -- review of the effects of treatment of childhood cancerHilary O D Critchley
Section of Obstetrics and Gynaecology, Department of Reproductive and Developmental Sciences, Centre for Reproductive Biology, University of Edinburgh, 37 Chalmers Street, Edinburgh EH3 9ET, UK
Hum Fertil (Camb) 5:61-6. 2002..The uterine factor remains a concern and women who are survivors of childhood cancer and their carers must recognize that these pregnancies will be at high risk...
Pregnancy in women who had cancer in childhoodAngela B Edgar
Department of Oncology, Royal Hospital for Sick Children, Edinburgh, UK
Eur J Cancer 43:1890-4. 2007..A number of large multi-centre studies, are underway and will provide new insights into pregnancy outcomes in survivors of childhood cancer...
Predicting age of ovarian failure after radiation to a field that includes the ovariesW Hamish B Wallace
Section of Child Life and Health, Department of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom
Int J Radiat Oncol Biol Phys 62:738-44. 2005..To predict the age at which ovarian failure is likely to develop after radiation to a field that includes the ovary in women treated for cancer...
The late endocrine effects of childhood cancer treatmentMark F H Brougham
Department of Paediatric Haematology and Oncology, Royal Hospital for Sick Children, 17 Millerfield Place, Edinburgh, EH9 1LW, UK
Pediatr Rehabil 5:191-201. 2002....
Fertility preservation in girls and young womenRichard A Anderson
Division of Reproductive and Developmental Science, MRC Centre for Reproductive Health, Queens Medical Research Institute, University of Edinburgh, Edinburgh, UK
Clin Endocrinol (Oxf) 75:409-19. 2011..Effective approaches for prepubertal boys are also required...
