Detail Information
Publications
Directed partial correlation: inferring large-scale gene regulatory network through induced topology disruptionsYinyin Yuan
Cancer Research UK, Cambridge Research Institute, Cambridge, United Kingdom
PLoS ONE 6:e16835. 2011..These results collectively suggest DPC is a versatile tool for genomics research. The R package DPC is available for download (http://code.google.com/p/dpcnet/)...
Patient-specific data fusion defines prognostic cancer subtypesYinyin Yuan
Cambridge Research Institute, Cancer Research UK, Cambridge, United Kingdom
PLoS Comput Biol 7:e1002227. 2011..We therefore demonstrate the importance of taking a patient-specific approach, using highly-flexible nonparametric Bayesian methods...
Penalized regression elucidates aberration hotspots mediating subtype-specific transcriptional responses in breast cancerYinyin Yuan
Cambridge Research Institute, Cancer Research UK, Li Ka Shing Centre, Cambridge CB2 0RE, UK
Bioinformatics 27:2679-85. 2011..Thus, it is important to develop computational approaches capable of inferring differential connectivity of regulatory networks in different cellular contexts...
