Research Topics
| Katja WiechSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Anterior insula integrates information about salience into perceptual decisions about painKatja Wiech
Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford, UK
J Neurosci 30:16324-31. 2010..These findings provide evidence that the anterior insula and MCC as a "salience network" integrate information about the significance of an impending stimulation into perceptual decision-making in the context of pain...
Neurocognitive aspects of pain perceptionKatja Wiech
Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
Trends Cogn Sci 12:306-13. 2008..Taking placebo-induced analgesia as an example, we discuss the contribution of attention, expectation and reappraisal as three basic mechanisms that are important for the cognitive modulation of pain...
An fMRI study measuring analgesia enhanced by religion as a belief systemKatja Wiech
Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Oxford, UK
Pain 139:467-76. 2008..We suggest that religious belief might provide a framework that allows individuals to engage known pain-regulatory brain processes...
The influence of negative emotions on pain: behavioral effects and neural mechanismsKatja Wiech
Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
Neuroimage 47:987-94. 2009..We discuss possible neural mechanisms underlying this modulatory influence focusing on the periaqueductal grey (PAG), amygdala, anterior cingulate cortex (ACC) and anterior insula as key players in both, pain and affective processing...
Flexible cerebral connectivity patterns subserve contextual modulations of painMarkus Ploner
FMRIB Centre and Nuffield Department of Anaesthetics, University of Oxford, Oxford OX3 9DU, UK
Cereb Cortex 21:719-26. 2011....
Prestimulus functional connectivity determines pain perception in humansMarkus Ploner
Oxford Centre for Functional Magnetic Resonance Imaging of Brain, Department of Clinical Neurology, University of Oxford, UK
Proc Natl Acad Sci U S A 107:355-60. 2010..We conclude that variations in functional connectivity underlie personality-related differences in individual susceptibility to pain...
The effect of treatment expectation on drug efficacy: imaging the analgesic benefit of the opioid remifentanilUlrike Bingel
Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences Division of Anaesthetics, University of Oxford, OX3 9DU Oxford, UK
Sci Transl Med 3:70ra14. 2011..We propose that it may be necessary to integrate patients' beliefs and expectations into drug treatment regimes alongside traditional considerations in order to optimize treatment outcomes...
Anterolateral prefrontal cortex mediates the analgesic effect of expected and perceived control over painKatja Wiech
Wellcome Department of Imaging Neuroscience, Institute of Neurology, London WC1N 3BG, United Kingdom
J Neurosci 26:11501-9. 2006..Failure to activate right alPFC may explain the maladaptive effects of strong general control beliefs during uncontrollable pain...
Tactile discrimination, but not tactile stimulation alone, reduces chronic limb painG Lorimer Moseley
Pain Imaging Neuroscience Group, Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, South Parks Road, Oxford OX13QX, UK
Pain 137:600-8. 2008..These gains were maintained at three-month follow-up. We conclude that tactile stimulation can decrease pain and increase tactile acuity when patients are required to discriminate between the type and location of tactile stimuli...
Pain relief as an opponent process: a psychophysical investigationSiri Leknes
Oxford Centre for Functional MRI of the Brain, Clinical Neurology and Nuffield Department of Anaesthetics, Oxford University, John Radcliffe Hospital, Oxford, UK
Eur J Neurosci 28:794-801. 2008..Importantly, the high relief pleasantness ratings confirmed the hypothesized link between relief and reward...
Dyspnoea and the brainMari Herigstad
Nuffield Department of Clinical Neuroscience, University of Oxford, John Radcliffe Hospital, Level 6, West Wing, Oxford OX3 9DU, UK
Respir Med 105:809-17. 2011..A better understanding of the brain processes underlying dyspnoea perception will lead to new therapies that will improve quality of life for a very large group of patients...
The effect of tactile discrimination training is enhanced when patients watch the reflected image of their unaffected limb during trainingG Lorimer Moseley
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
Pain 144:314-9. 2009....
