Research Topics
Species | Marcin R PrzewlokaSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
The kinetochore and the centromere: a working long distance relationshipMarcin R Przewloka
University of Cambridge, Department of Genetics, Cambridge, CB2 3EH, United Kingdom
Annu Rev Genet 43:439-65. 2009....
Molecular analysis of core kinetochore composition and assembly in Drosophila melanogasterMarcin R Przewloka
Cancer Research UK, Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Cambridge, United Kingdom
PLoS ONE 2:e478. 2007..Although Drosophila is a classical model organism for studies of chromosome segregation, little is known about the organization of its kinetochores...
CENP-C is a structural platform for kinetochore assemblyMarcin R Przewloka
Department of Genetics, University of Cambridge, Cambridge, UK
Curr Biol 21:399-405. 2011..Thus, the N-terminal part of Drosophila CENP-C is sufficient to recruit core kinetochore components and acts as the principal linkage between centromere and kinetochore during mitosis...
Nessun Dorma, a novel centralspindlin partner, is required for cytokinesis in Drosophila spermatocytesEmilie Montembault
Department of Pathology, University of Cambridge, Cambridge CB2 1QP, England, UK
J Cell Biol 191:1351-65. 2010..Our findings indicate that Nesd is a novel carbohydrate-binding protein that functions together with centralspindlin in late cytokinesis, thus highlighting the importance of glycosylation in this process...
Isolation of protein complexes involved in mitosis and cytokinesis from Drosophila cultured cellsPier Paolo D'Avino
Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Cambridge, UK
Methods Mol Biol 545:99-112. 2009..Although this method has proven very successful in isolating mitotic and cytokinetic complexes, it can also be used to characterise protein complexes involved in many other cellular processes...
Drosophila Mis12 complex acts as a single functional unit essential for anaphase chromosome movement and a robust spindle assembly checkpointZsolt Venkei
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom
Genetics 187:131-40. 2011..Importantly our results indicate that core structural elements of the inner plate of the kinetochore have a greater contribution to faithful chromosome segregation in anaphase than in earlier stages of mitosis...
Recruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complexPier Paolo D'Avino
Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Cambridge, United Kingdom
PLoS ONE 2:e572. 2007..Their roles during cytokinesis, however, are not well understood because the requirement of these kinases during early stages of mitosis complicates the study of their functions after anaphase onset...
