Detail Information
Publications
Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion positionLavinia Paternoster
MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
Am J Hum Genet 90:478-85. 2012..Our findings show that common variants within this gene also influence normal craniofacial development...
OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohortsL Paternoster
Medical Research Council Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, United Kingdom
J Clin Endocrinol Metab 95:3940-8. 2010..Several single-nucleotide polymorphisms (SNPs) have been reliably associated with areal bone mineral density (aBMD) in genome-wide association studies of mostly older subjects...
Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on boneLavinia Paternoster
University of Bristol, Bristol, UK
PLoS Genet 6:e1001217. 2010..This finding implicates RANKL as a locus containing variation associated with volumetric bone density and provides further insight into the mechanism by which the RANK/RANKL/OPG pathway may be involved in skeletal development...
Adult height variants affect birth length and growth rate in childrenLavinia Paternoster
MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
Hum Mol Genet 20:4069-75. 2011..SNPs associated with adult height influence birth length and have an increasing effect on growth from late infancy through to late childhood. By age 10, they explain half the height variance (?5%) of that explained in adults (?10%)...
