M R Novelli

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Unusual presentation of Lynch Syndrome
    Veronica Pcc Yu
    Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK
    Hered Cancer Clin Pract 7:12. 2009
  2. ncbi Haematopoietic development and immunological function in the absence of cathepsin D
    Calogero Tulone
    Division of Infection and Immunity, UCL, London, UK
    BMC Immunol 8:22. 2007
  3. ncbi Tumor burden and clonality in multiple intestinal neoplasia mouse/normal mouse aggregation chimeras
    M R Novelli
    Department of Histopathology, University College London, London WC1E 6JJ, United Kingdom
    Proc Natl Acad Sci U S A 96:12553-8. 1999
  4. ncbi X-inactivation patch size in human female tissue confounds the assessment of tumor clonality
    Marco Novelli
    Department of Histopathology, Rockefeller Building, University Street, University College London Hospitals, London WC1E 6JJ, United Kingdom
    Proc Natl Acad Sci U S A 100:3311-4. 2003
  5. ncbi DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
    Marco Novelli
    Department of Pathology, University College London NHS Trust, University Street, London, UK
    Histopathology 57:259-70. 2010
  6. ncbi Radiofrequency ablation is effective for the treatment of high-grade dysplasia in Barrett's esophagus after failed photodynamic therapy
    J M Dunn
    National Medical Laser Centre, Department of Surgery, University College London, London, UK
    Endoscopy 43:627-30. 2011
  7. ncbi Gastrointestinal Kaposi's sarcoma: CD117 expression and the potential for misdiagnosis as gastrointestinal stromal tumour
    J R Parfitt
    Department of Pathology, London Health Sciences, London, Ontario, Canada
    Histopathology 52:816-23. 2008
  8. ncbi Comparison of nuclear texture analysis and image cytometric DNA analysis for the assessment of dysplasia in Barrett's oesophagus
    J M Dunn
    Department of Surgery, National Medical Laser Centre, University College London, London, UK
    Br J Cancer 105:1218-23. 2011
  9. ncbi Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy
    J M Dunn
    Department of Surgery, National Medical Laser Centre, University College London, 67 73 Riding House Street, London W1W 7EJ, UK
    Br J Cancer 102:1608-17. 2010
  10. ncbi Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus
    S J Leedham
    Histopathology Unit, Cancer Research UK, London, UK
    Gut 57:1041-8. 2008

Collaborators

Detail Information

Publications11

  1. ncbi Unusual presentation of Lynch Syndrome
    Veronica Pcc Yu
    Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK
    Hered Cancer Clin Pract 7:12. 2009
    ..We describe a family of Lynch Syndrome with an hMLH1 mutation, that harbours an unusual tumour spectrum and its diagnostic and management challenges...
  2. ncbi Haematopoietic development and immunological function in the absence of cathepsin D
    Calogero Tulone
    Division of Infection and Immunity, UCL, London, UK
    BMC Immunol 8:22. 2007
    ..This study examines the reconstitution and function of the immune system in the absence of cathepsin D, using bone marrow radiation chimaeras in which all haematopoietic cells are derived from cathepsin D deficient mice...
  3. ncbi Tumor burden and clonality in multiple intestinal neoplasia mouse/normal mouse aggregation chimeras
    M R Novelli
    Department of Histopathology, University College London, London WC1E 6JJ, United Kingdom
    Proc Natl Acad Sci U S A 96:12553-8. 1999
    ....
  4. ncbi X-inactivation patch size in human female tissue confounds the assessment of tumor clonality
    Marco Novelli
    Department of Histopathology, Rockefeller Building, University Street, University College London Hospitals, London WC1E 6JJ, United Kingdom
    Proc Natl Acad Sci U S A 100:3311-4. 2003
    ..Results show that the patch size is relatively large in both the human colon and breast, confounding assessment of tumor clonality with traditional X-inactivation studies...
  5. ncbi DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
    Marco Novelli
    Department of Pathology, University College London NHS Trust, University Street, London, UK
    Histopathology 57:259-70. 2010
    ..The aim of this study was to examine the staining quality, sensitivity, specificity and utility of antibodies used commonly in GIST diagnosis...
  6. ncbi Radiofrequency ablation is effective for the treatment of high-grade dysplasia in Barrett's esophagus after failed photodynamic therapy
    J M Dunn
    National Medical Laser Centre, Department of Surgery, University College London, London, UK
    Endoscopy 43:627-30. 2011
    ..The rate of strictures was 7?% (1/14) and there was a low rate of buried glands (0.5?% follow-up biopsies). These data suggest RFA is both safe and effective for eradication of high-grade dysplasia in patients in whom PDT has failed...
  7. ncbi Gastrointestinal Kaposi's sarcoma: CD117 expression and the potential for misdiagnosis as gastrointestinal stromal tumour
    J R Parfitt
    Department of Pathology, London Health Sciences, London, Ontario, Canada
    Histopathology 52:816-23. 2008
    ..The aim was to evaluate the clinicopathological features of GI KS, including the expression of CD117 with and without antigen retrieval...
  8. ncbi Comparison of nuclear texture analysis and image cytometric DNA analysis for the assessment of dysplasia in Barrett's oesophagus
    J M Dunn
    Department of Surgery, National Medical Laser Centre, University College London, London, UK
    Br J Cancer 105:1218-23. 2011
    ..We aimed to evaluate NT as a marker of dysplasia in BO and compare with image cytometric DNA analysis (ICM)...
  9. ncbi Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy
    J M Dunn
    Department of Surgery, National Medical Laser Centre, University College London, 67 73 Riding House Street, London W1W 7EJ, UK
    Br J Cancer 102:1608-17. 2010
    ..Our aim was to determine the accuracy of ICDA vs FC, and evaluate DNA ploidy as a prognostic biomarker after histologically successful treatment with photodynamic therapy (PDT)...
  10. ncbi Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus
    S J Leedham
    Histopathology Unit, Cancer Research UK, London, UK
    Gut 57:1041-8. 2008
    ..The histogenesis of Barrett's metaplasia and neo-squamous islands has never been demonstrated. We investigated the oesophageal gland squamous ducts as the source of both epithelial sub-types...
  11. ncbi Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations
    C Thirlwell
    Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, 44, Lincoln s Inn Fields, London WC2A 3PX, UK
    Br J Cancer 96:1729-34. 2007
    ..We suggest that, at least in some cases, the MCRA phenotype results from germline variation that acts subsequent to tumour initiation, perhaps by causing more rapid or more likely progression from microadenoma to macroadenoma...