Research Topics
Species | Marilyn MonkSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Isolation of novel developmental genes from human germ cell, oocyte and embryo cDNA by differential displayM Monk
Molecular Embryology Unit, Institute of Child Health, London, UK
Reprod Fertil Dev 13:51-7. 2001..They represent candidate genes regulating these functions for targeting in clinical research in human reproduction, stem cell differentiation and cancer...
Of microbes, mice and manM Monk
Molecular Embryology Unit, London, England
Int J Dev Biol 45:497-507. 2001....
Human embryonic genes re-expressed in cancer cellsM Monk
Molecular Embryology Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Oncogene 20:8085-91. 2001..Genes specific to this unique phase of the human life cycle and not expressed in somatic cells may have greater potential for targeting in cancer treatment...
Mammalian embryonic development--insights from studies on the X chromosomeM Monk
Molecular Embryology Unit, Institute of Child Health, London, UK
Cytogenet Genome Res 99:200-9. 2002..Indeed several paradigm shifts occurred as a result of these studies and these are highlighted in this review...
Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation developmentMarilyn Monk
Molecular Embryology Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Mol Hum Reprod 14:347-55. 2008....
Identification and characterisation of known and novel transcripts expressed during the final stages of human oocyte maturationTetsuya Goto
Centre for Early Human Development, Institute of Reproduction and Development, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
Mol Reprod Dev 62:13-28. 2002..1-kb transcript is restricted to the testis and ovary, and its expression correlates with cell pluripotency in that it is expressed in embryonal carcinoma cells, but not in their differentiated derivative cells...
ECSA/DPPA2 is an embryo-cancer antigen that is coexpressed with cancer-testis antigens in non-small cell lung cancerThomas John
Ludwig Institute for Cancer Research, Melbourne Centre for Clinical Sciences, Victoria, Australia
Clin Cancer Res 14:3291-8. 2008..We hypothesized that ECSA/DPPA2 would be quiescent in most normal tissues but expressed in cancers and may therefore be a useful target for immunotherapy...
