Research Topics
Species | A J MighellSummaryAffiliation: University of Leeds Country: UK Publications
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Detail Information
Publications
Mutations in the beta propeller WDR72 cause autosomal-recessive hypomaturation amelogenesis imperfectaWalid El-Sayed
Leeds Institute of Molecular Medicine, St James s University Hospital, University of Leeds, LS9 7TF Leeds, UK
Am J Hum Genet 85:699-705. 2009..This raises the intriguing possibility that WDR72 is critical to ameloblast vesicle turnover during enamel maturation...
Human tenascin-C: identification of a novel type III repeat in oral cancer and of novel splice variants in normal, malignant and reactive oral mucosaeA J Mighell
Molecular Medicine Unit, St James s University Hospital, Leeds, UK
Int J Cancer 72:236-40. 1997..Thus, we have demonstrated that human tenascin-C transcripts generate a complex but selected repertoire of different alternative splice products...
Alu sequencesA J Mighell
Molecular Medicine Unit, The University of Leeds, St James s University Hospital, UK
FEBS Lett 417:1-5. 1997..The multiple influences of Alu sequences on RNA polymerase II-mediated gene expression and the presence of Alu sequences in RNA polymerase III-generated transcripts are discussed...
An overview of the complexities and subtleties of immunohistochemistryA J Mighell
Leeds Dental Institute, UK
Oral Dis 4:217-23. 1998....
Vertebrate pseudogenesA J Mighell
Molecular Medicine Unit, The University of Leeds, Clinical Sciences Building, St James s University Hospital, Leeds, UK
FEBS Lett 468:109-14. 2000..As the sequences of different genomes are characterised, the recognition and interpretation of pseudogene sequences will become more important and have a greater impact in the field of molecular genetics...
Clinical medical sciences for undergraduate dental students in the United Kingdom and Ireland - a curriculumA J Mighell
The University of Leeds, Leeds Dental Institute, Leeds, UK
Eur J Dent Educ 15:179-88. 2011..This document will act as a focus for a more unified approach to the outcomes required by graduates of the participating centres and act as a catalyst for future developments that ultimately aim to enhance the quality of patient care...
Hypomaturation amelogenesis imperfecta due to WDR72 mutations: a novel mutation and ultrastructural analyses of deciduous teethW El-Sayed
Leeds Dental Institute, University of Leeds, Leeds, UK
Cells Tissues Organs 194:60-6. 2011..Mutations in WDR72 have been identified in autosomal recessive hypomaturation amelogenesis imperfecta (AI)...
Ultrastructural analyses of deciduous teeth affected by hypocalcified amelogenesis imperfecta from a family with a novel Y458X FAM83H nonsense mutationW El-Sayed
Leeds Dental Institute, University of Leeds, UK
Cells Tissues Organs 191:235-9. 2010..Nonsense mutations in FAM83H are a recently described underlying cause of autosomal dominant (AD) hypocalcified amelogenesis imperfecta (AI)...
