Research Topics
| Stephen J MartinSummaryAffiliation: University of Edinburgh Country: UK Publications
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Detail Information
Publications
Retrograde amnesia: neither partial nor complete hippocampal lesions in rats result in preferential sparing of remote spatial memory, even after remindingStephen J Martin
Laboratory for Cognitive Neuroscience, Division of Neuroscience, University of Edinburgh, Crichton Street, Edinburgh EH8 9LE, Scotland, UK
Neuropsychologia 43:609-24. 2005..The nature of this role--in the storage, retrieval, or expression of memory--is discussed...
Synaptic plasticity and memory: an evaluation of the hypothesisS J Martin
Department and Centre for Neuroscience, University of Edinburgh, United Kingdom
Annu Rev Neurosci 23:649-711. 2000..We conclude that a wealth of data supports the notion that synaptic plasticity is necessary for learning and memory, but that little data currently supports the notion of sufficiency...
The rodent hippocampus and spatial memory: from synapses to systemsS J Martin
Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, University of Edinburgh, 1 George Square, Edinburgh, EH8 9JZ, UK
Cell Mol Life Sci 64:401-31. 2007....
Cortical plasticity: It's all the range!S J Martin
Department of Neuroscience, University of Edinburgh, Crichton Street, EH8 9LE, Edinburgh, UK
Curr Biol 11:R57-9. 2001..These findings support the view that activity-dependent synaptic plasticity is the brain's memory mechanism...
Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivoS J Martin
Department of Neuroscience, University of Edinburgh, Crichton Street, Edinburgh EH8 9LE, UK
Neuropharmacology 40:634-7. 2001..The present study reveals that pharmacological activation of mGluRs in vivo induces dentate EEG oscillations at the low end of the gamma frequency range, with peak activity just below 30 Hz...
New life in an old idea: the synaptic plasticity and memory hypothesis revisitedS J Martin
Hippocampus 12:609-36. 2002..A major challenge will be to determine whether such changes constitute the memory trace itself or play a less specific supporting role in the information processing that accompanies memory formation...
Forgetting, reminding, and remembering: the retrieval of lost spatial memoryLivia de Hoz
Laboratory for Cognitive Neuroscience, Centre and Division of Neuroscience, University of Edinburgh, Edinburgh, Scotland, United Kingdom
PLoS Biol 2:E225. 2004....
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptorNoboru H Komiyama
Division of Neuroscience, University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
J Neurosci 22:9721-32. 2002..A comparison of SynGAP and PSD-95 mutants suggests that PSD-95 couples NMDARs to multiple downstream signaling pathways with very different roles in LTP and learning...
Dopaminergic modulation of the persistence of one-trial hippocampus-dependent memoryColin M O'Carroll
Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh EH8 9JZ, United Kingdom
Learn Mem 13:760-9. 2006..The complementary effects of D1/D5 receptor blockade on the persistence of LTP and the duration of memory are consistent with the idea that changes in synaptic strength underlie memory...
Faster forgetting contributes to impaired spatial memory in the PDAPP mouse: deficit in memory retrieval associated with increased sensitivity to interference?Stephanie Daumas
Centre for Cognitive and Neural Systems University of Edinburgh, Edinburgh EH8 9JZ, Scotland
Learn Mem 15:625-32. 2008..This interpretation of one aspect of the cognitive deficit in human mutant APP mice has parallels to deficits observed in patients with Alzheimer's disease, further supporting the validity of transgenic models of the disease...
Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memoryR G M Morris
Division of Centre for Neuroscience, The University of Edingurgh, Edinburgh, UK
Philos Trans R Soc Lond B Biol Sci 358:773-86. 2003....
(R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivoS J Martin
Centre for Neuroscience and Department of Pharmacology, University of Edinburgh, UK
Neuropharmacology 36:1339-54. 1997....
Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloidGuiquan Chen
Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, Edinburgh EH8 9JZ, United Kingdom
J Neurosci 27:2654-62. 2007....
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's diseaseG Chen
Department of Neuroscience, University of Edinburgh, UK
Nature 408:975-9. 2000....
Interrogating rodents regarding their object and spatial memoryRobert E Clark
Department of Psychiatry, 0603 University of California San Diego and Veterans Affairs Medical Center, San Diego, La Jolla, CA 92093, USA
Curr Opin Neurobiol 15:593-8. 2005..Relevant to these issues, there have been substantial developments in the methods used to evaluate two of the most frequently studied forms of memory in the rodent -- recognition memory and spatial memory...
