Y K Loke

Summary

Affiliation: University of East Anglia
Country: UK

Publications

  1. ncbi Internet treatment of sexually transmitted infections - a public health hazard?
    Roberto Vivancos
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK
    BMC Public Health 7:333. 2007
  2. ncbi Identifying systematic reviews of the adverse effects of health care interventions
    Su Golder
    Centre for Reviews and Dissemination CRD, University of York, York, YO10 5DD, UK
    BMC Med Res Methodol 6:22. 2006
  3. ncbi Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studies
    Fujian Song
    School of Medicine, Health Policy and Practice, University of East Anglia, Earlham Road, Norwich NR4 7TJ, UK
    BMC Med Res Methodol 9:79. 2009
  4. ncbi Room for improvement? A survey of the methods used in systematic reviews of adverse effects
    Su Golder
    Centre for Reviews and Dissemination, University of York, York, YO10 5DD, UK
    BMC Med Res Methodol 6:3. 2006
  5. ncbi Bisphosphonates and atrial fibrillation: systematic review and meta-analysis
    Yoon Kong Loke
    School of Medicine, University of East Anglia, Norwich, UK
    Drug Saf 32:219-28. 2009
  6. ncbi Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies
    Yoon K Loke
    School of Medicine, University of East Anglia, Norwich NR4 7TJ, UK
    Thorax 66:699-708. 2011
  7. ncbi Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis
    Yoon K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK
    Thorax 65:884-90. 2010
  8. ncbi Dabigatran and rivaroxaban for prevention of venous thromboembolism--systematic review and adjusted indirect comparison
    Y K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    J Clin Pharm Ther 36:111-24. 2011
  9. ncbi Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies
    Yoon Kong Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK
    BMJ 342:d1309. 2011
  10. ncbi Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis
    Yoon K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    CMAJ 180:32-9. 2009

Detail Information

Publications22

  1. ncbi Internet treatment of sexually transmitted infections - a public health hazard?
    Roberto Vivancos
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK
    BMC Public Health 7:333. 2007
    ..We conducted an internet search to determine the availability of treatments for STIs and the nature of information provided by vendors of these treatments...
  2. ncbi Identifying systematic reviews of the adverse effects of health care interventions
    Su Golder
    Centre for Reviews and Dissemination CRD, University of York, York, YO10 5DD, UK
    BMC Med Res Methodol 6:22. 2006
    ..In order to carry out a methodological research survey of systematic reviews of adverse effects we needed to retrieve a sample of systematic reviews in which the primary outcome is an adverse effect or effects...
  3. ncbi Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studies
    Fujian Song
    School of Medicine, Health Policy and Practice, University of East Anglia, Earlham Road, Norwich NR4 7TJ, UK
    BMC Med Res Methodol 9:79. 2009
    ..We conducted a meta-analysis to ascertain the strength and consistency of the association between study results and formal publication...
  4. ncbi Room for improvement? A survey of the methods used in systematic reviews of adverse effects
    Su Golder
    Centre for Reviews and Dissemination, University of York, York, YO10 5DD, UK
    BMC Med Res Methodol 6:3. 2006
    ..Although the methods for conducting systematic reviews of efficacy are well established, there is much less guidance on how systematic reviews of adverse effects should be performed...
  5. ncbi Bisphosphonates and atrial fibrillation: systematic review and meta-analysis
    Yoon Kong Loke
    School of Medicine, University of East Anglia, Norwich, UK
    Drug Saf 32:219-28. 2009
    ..Bisphosphonates are widely used in osteoporosis, but there have been concerns about a potential link between bisphosphonate therapy and atrial fibrillation...
  6. ncbi Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies
    Yoon K Loke
    School of Medicine, University of East Anglia, Norwich NR4 7TJ, UK
    Thorax 66:699-708. 2011
    ..The effect of inhaled corticosteroids (ICS) on fracture risk in patients with chronic obstructive pulmonary disease (COPD) remains uncertain. The aim of this study was to evaluate the association between ICS and fractures in COPD...
  7. ncbi Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis
    Yoon K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK
    Thorax 65:884-90. 2010
    ..Several scoring systems have been used to predict mortality in patients with community-acquired pneumonia. The properties of commonly used risk stratification scales were systematically reviewed...
  8. ncbi Dabigatran and rivaroxaban for prevention of venous thromboembolism--systematic review and adjusted indirect comparison
    Y K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    J Clin Pharm Ther 36:111-24. 2011
    ..14 (95% CI 0.80-1.64). WHAT IS NEW AND CONCLUSION: Rivaroxaban may be more effective than dabigatran for prevention of VTE after elective orthopaedic surgery but might also slightly increase the risk of haemorrhage...
  9. ncbi Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies
    Yoon Kong Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK
    BMJ 342:d1309. 2011
    ..To determine the comparative effects of the thiazolidinediones (rosiglitazone and pioglitazone) on myocardial infarction, congestive heart failure, and mortality in patients with type 2 diabetes...
  10. ncbi Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis
    Yoon K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    CMAJ 180:32-9. 2009
    ..Rosiglitazone and pioglitazone may increase the incidence of fractures. We aimed to determine systematically the risk of fractures associated with thiazolidinedione therapy and to evaluate the effect of the therapy on bone density...
  11. ncbi Meta-analysis: gastrointestinal bleeding due to interaction between selective serotonin uptake inhibitors and non-steroidal anti-inflammatory drugs
    Y K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Aliment Pharmacol Ther 27:31-40. 2008
    ....
  12. ncbi Systematic reviews of adverse effects: framework for a structured approach
    Yoon K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    BMC Med Res Methodol 7:32. 2007
    ..A detailed discussion of why, how and when to include adverse effects in a systematic review, is required...
  13. ncbi The potassium-channel syndrome: does it exist?
    Yoon K Loke
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich NR4 7TJ, UK
    Lancet 365:1834-6. 2005
  14. ncbi Assessing the benefit-harm balance at the bedside
    Yoon Kong Loke
    School of Medicine, Health Policy and Practice University of East Anglia, Norwich NR4 7TJ
    BMJ 329:7-8. 2004
  15. ncbi Case reports of suspected adverse drug reactions--systematic literature survey of follow-up
    Yoon Kong Loke
    School of Medicine, Health Policy, and Practice, University of East Anglia, Norwich NR4 7TJ
    BMJ 332:335-9. 2006
    ..To determine whether anecdotal reports of suspected adverse drug reactions are valuable early warning signals...
  16. ncbi Risk of myocardial infarction and cardiovascular death associated with inhaled corticosteroids in COPD
    Y K Loke
    Dept of Clinical Pharmacology, University of East Anglia, Norwich, UK
    Eur Respir J 35:1003-21. 2010
    ..These conflicting findings need to be clarified through further research...
  17. ncbi Methodological problems in the use of indirect comparisons for evaluating healthcare interventions: survey of published systematic reviews
    Fujian Song
    Faculty of Health, University of East Anglia, Norwich NR4 7TJ
    BMJ 338:b1147. 2009
    ..To investigate basic assumptions and other methodological problems in the application of indirect comparison in systematic reviews of competing healthcare interventions...
  18. ncbi Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel
    C S Kwok
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK
    Aliment Pharmacol Ther 31:810-23. 2010
    ..Recent studies have suggested an adverse interaction between proton pump inhibitors (PPI) and clopidogrel...
  19. ncbi Dissemination and publication of research findings: an updated review of related biases
    F Song
    School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Health Technol Assess 14:iii, ix-xi, 1-193. 2010
    ....
  20. ncbi Atrial fibrillation and incidence of dementia: a systematic review and meta-analysis
    C S Kwok
    Stroke Research Group, Gunthorpe Acute Stroke Unit, Academic Department of Medicine for the Elderly, Norfolk and Norwich University Hospital, Norwich, Norfolk, UK
    Neurology 76:914-22. 2011
    ..Previous systematic reviews that examined whether atrial fibrillation (AF) is associated with dementia have relied on different study designs (including retrospective ones) and did not evaluate risk using meta-analysis...
  21. ncbi Is there evidence for biased reporting of published adverse effects data in pharmaceutical industry-funded studies?
    Su Golder
    CRD, University of York, York and School of Medicine, University of East Anglia, Norwich, UK
    Br J Clin Pharmacol 66:767-73. 2008
    ..To investigate whether adverse effects data for the sponsor's product are presented more favourably in pharmaceutical industry-funded studies than in non-industry-funded studies...
  22. ncbi Aspirin for the prevention of cardiovascular disease: calculating benefit and harm in the individual patient
    Yoon Kong Loke
    Department of Clinical Pharmacology, University of Oxford, Radcliffe Infirmary, Oxford OX2 6HE
    Br J Clin Pharmacol 55:282-7. 2003
    ..To estimate the absolute reduction in the risk of cardiovascular events and absolute increase in gastrointestinal haemorrhage associated with aspirin for individuals with different baseline risks...