Salim I Khakoo

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. ncbi MHC class I receptors on natural killer cells: on with the old and in with the new
    Salim I Khakoo
    Division of Infection Inflammation and Repair, School of Medicine, University of Southampton, Mailpoint 811, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    Clin Sci (Lond) 105:127-40. 2003
  2. ncbi HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection
    Salim I Khakoo
    Liver Group, Division of Infection, Inflammation, and Repair, Southampton University, Southampton 5016 6YD, UK
    Science 305:872-4. 2004
  3. ncbi Hanging in the balance. KIR and their role in disease
    Anthony P Williams
    Division of Cancer Sciences, Southampton University School of Medicine, Southampton, UK, SO16 6YD
    Mol Interv 5:226-40. 2005
  4. ncbi Age-related macular degeneration is associated with the HLA-Cw*0701 Genotype and the natural killer cell receptor AA haplotype
    Srinivas V Goverdhan
    Division of Clinical Neurosciences, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
    Invest Ophthalmol Vis Sci 49:5077-82. 2008
  5. ncbi KIR and disease: a model system or system of models?
    Salim I Khakoo
    Cancer Sciences Division, University of Southampton, Southampton General Hospital, Southampton, UK
    Immunol Rev 214:186-201. 2006
  6. ncbi Conservation and variation in human and common chimpanzee CD94 and NKG2 genes
    Benny P Shum
    Department of Structural Biology, Stanford University School of Medicine, 299 Campus Drive West, Stanford, CA 94305, USA
    J Immunol 168:240-52. 2002
  7. ncbi The inhibitory receptor NKG2A determines lysis of vaccinia virus-infected autologous targets by NK cells
    Collin R Brooks
    The School of Medicine, Southampton University, Southampton, United Kingdom
    J Immunol 176:1141-7. 2006
  8. ncbi The D0 domain of KIR3D acts as a major histocompatibility complex class I binding enhancer
    Salim I Khakoo
    Department of Structural Biology, Stanford University School of Medicine, CA 94305, USA
    J Exp Med 196:911-21. 2002

Detail Information

Publications8

  1. ncbi MHC class I receptors on natural killer cells: on with the old and in with the new
    Salim I Khakoo
    Division of Infection Inflammation and Repair, School of Medicine, University of Southampton, Mailpoint 811, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    Clin Sci (Lond) 105:127-40. 2003
    ..This review details the interaction of NK cell receptors with MHC class I and discusses their unexpectedly rapid evolution...
  2. ncbi HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection
    Salim I Khakoo
    Liver Group, Division of Infection, Inflammation, and Repair, Southampton University, Southampton 5016 6YD, UK
    Science 305:872-4. 2004
    ..The data strongly suggest that inhibitory NK cell interactions are important in determining antiviral immunity and that diminished inhibitory responses confer protection against HCV...
  3. ncbi Hanging in the balance. KIR and their role in disease
    Anthony P Williams
    Division of Cancer Sciences, Southampton University School of Medicine, Southampton, UK, SO16 6YD
    Mol Interv 5:226-40. 2005
    ..This review summarizes the major features of these genes and discusses how they may be involved in both disease pathogenesis and its amelioration...
  4. ncbi Age-related macular degeneration is associated with the HLA-Cw*0701 Genotype and the natural killer cell receptor AA haplotype
    Srinivas V Goverdhan
    Division of Clinical Neurosciences, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
    Invest Ophthalmol Vis Sci 49:5077-82. 2008
    ..To determine the association of human leukocyte antigen (HLA) C and its cognate killer cell immunoglobulin-like receptor (KIR) ligands with age-related macular degeneration (AMD)...
  5. ncbi KIR and disease: a model system or system of models?
    Salim I Khakoo
    Cancer Sciences Division, University of Southampton, Southampton General Hospital, Southampton, UK
    Immunol Rev 214:186-201. 2006
    ..In this review, we summarize the findings from a number of disease association studies and discuss these in the context of the activating and inhibitory roles of the members of this gene family...
  6. ncbi Conservation and variation in human and common chimpanzee CD94 and NKG2 genes
    Benny P Shum
    Department of Structural Biology, Stanford University School of Medicine, 299 Campus Drive West, Stanford, CA 94305, USA
    J Immunol 168:240-52. 2002
    ..Each species gave distinctive typing patterns, with NKG2A and CD94 being most conserved. Seven different NK complex genotypes within the panel of 48 common chimpanzees were due to differences in Pt-NKG2C and Pt-NKG2D genes...
  7. ncbi The inhibitory receptor NKG2A determines lysis of vaccinia virus-infected autologous targets by NK cells
    Collin R Brooks
    The School of Medicine, Southampton University, Southampton, United Kingdom
    J Immunol 176:1141-7. 2006
    ....
  8. ncbi The D0 domain of KIR3D acts as a major histocompatibility complex class I binding enhancer
    Salim I Khakoo
    Department of Structural Biology, Stanford University School of Medicine, CA 94305, USA
    J Exp Med 196:911-21. 2002
    ..This modulatory role for D0 is compatible with natural loss of expression of the D0 domain, a repeated event in the evolution of functional KIR genes...