Research Topics
| Raju KapoorSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Sodium channel blockers and neuroprotection in multiple sclerosis using lamotrigineRaju Kapoor
National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N3BG, UK
J Neurol Sci 274:54-6. 2008..Clinical trials of neuroprotection using blockers of sodium channels are now under way. There is no agreement yet on several aspects of trial design, but the situation should become clearer once the results of these trials are reported...
Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallel-group trialRaju Kapoor
Department of Neuroinflammation, National Hospital for Neurology and Neurosurgery and the Institute of Neurology, Queen Square, London, UK
Lancet Neurol 9:681-8. 2010..In this phase 2 trial, we aimed to assess whether the sodium-channel blocker lamotrigine is also neuroprotective in patients with secondary progressive multiple sclerosis...
Axonal protection achieved in a model of multiple sclerosis using lamotrigineDavid A Bechtold
Department of Clinical Neuroscience, King's College London, Guy's Campus, National Hospital for Neurology and Neurosurgery, London, UK
J Neurol 253:1542-51. 2006..5 %+/-38.5; lamotrigine: 10.4 %+/-12.5, P<0.01). The findings suggest that lamotrigine may provide a novel avenue for axonal protection in MS...
Neuroprotection in multiple sclerosis: therapeutic strategies and clinical trial designRaju Kapoor
National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
Curr Opin Neurol 19:255-9. 2006..This review considers the rationale for different therapeutic strategies for neuroprotection and discusses the controversies of trial design...
