D T Jones

Summary

Affiliation: University of Warwick
Country: UK

Publications

  1. ncbi Successful recognition of protein folds using threading methods biased by sequence similarity and predicted secondary structure
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, United Kingdom
    Proteins . 1999
  2. ncbi Progress in protein structure prediction
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, UK
    Curr Opin Struct Biol 7:377-87. 1997
  3. ncbi Do transmembrane protein superfolds exist?
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, UK
    FEBS Lett 423:281-5. 1998
  4. ncbi GenTHREADER: an efficient and reliable protein fold recognition method for genomic sequences
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    J Mol Biol 287:797-815. 1999
  5. ncbi Protein secondary structure prediction based on position-specific scoring matrices
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, United Kingdom
    J Mol Biol 292:195-202. 1999
  6. ncbi What are the baselines for protein fold recognition?
    L J McGuffin
    Bioinformatics Group, Department of Biological Sciences, Brunel University, Uxbridge UB8 3PH, UK
    Bioinformatics 17:63-72. 2001
  7. ncbi Protein structure prediction in the postgenomic era
    D T Jones
    Department of Biological Sciences, Brunel University, Uxbridge, UB8 3PH, UK
    Curr Opin Struct Biol 10:371-9. 2000
  8. ncbi Protein structure prediction in genomics
    D T Jones
    Department of Biological Sciences, Brunel University, Uxbridge, UK
    Brief Bioinform 2:111-25. 2001
  9. ncbi Potential energy functions for threading
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, UK
    Curr Opin Struct Biol 6:210-6. 1996
  10. ncbi Predicting novel protein folds by using FRAGFOLD
    D T Jones
    Department of Biological Sciences, Brunel University, Uxbridge, Middlesex, United Kingdom
    Proteins . 2001

Collaborators

  • L J McGuffin
  • V Fulop
  • K Bryson

Detail Information

Publications11

  1. ncbi Successful recognition of protein folds using threading methods biased by sequence similarity and predicted secondary structure
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, United Kingdom
    Proteins . 1999
    ..Of these 20 domains, we correctly assigned the folds in 10 cases...
  2. ncbi Progress in protein structure prediction
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, UK
    Curr Opin Struct Biol 7:377-87. 1997
    ..Unfortunately, there is little evidence of this transition happening in the field of ab initio tertiary-structure prediction...
  3. ncbi Do transmembrane protein superfolds exist?
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, UK
    FEBS Lett 423:281-5. 1998
    ....
  4. ncbi GenTHREADER: an efficient and reliable protein fold recognition method for genomic sequences
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    J Mol Biol 287:797-815. 1999
    ..In some cases, however, only one domain of the protein can be predicted, giving a total coverage of 30 % when calculated as a fraction of the number of amino acid residues in the whole proteome...
  5. ncbi Protein secondary structure prediction based on position-specific scoring matrices
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, United Kingdom
    J Mol Biol 292:195-202. 1999
    ..Given the success of the method in CASP3, it is reasonable to be confident that the evaluation presented here gives a fair indication of the performance of the method in general...
  6. ncbi What are the baselines for protein fold recognition?
    L J McGuffin
    Bioinformatics Group, Department of Biological Sciences, Brunel University, Uxbridge UB8 3PH, UK
    Bioinformatics 17:63-72. 2001
    ....
  7. ncbi Protein structure prediction in the postgenomic era
    D T Jones
    Department of Biological Sciences, Brunel University, Uxbridge, UB8 3PH, UK
    Curr Opin Struct Biol 10:371-9. 2000
    ..There are limitations to this approach to gene identification and a survey of the expected reliability of different protein structure prediction techniques has been undertaken...
  8. ncbi Protein structure prediction in genomics
    D T Jones
    Department of Biological Sciences, Brunel University, Uxbridge, UK
    Brief Bioinform 2:111-25. 2001
    ..The applicability of this approach to gene characterisation is reviewed, along with a brief survey of the reliability of large-scale protein structure prediction methods and the prospects for the development of new prediction methods...
  9. ncbi Potential energy functions for threading
    D T Jones
    Department of Biological Sciences, University of Warwick, Coventry, UK
    Curr Opin Struct Biol 6:210-6. 1996
    ..Despite promising initial results, these methods are clearly not yet fully mature and many groups are now working on different aspects of the methods involved in the hope of increasing the reliability and sensitivity of these tools...
  10. ncbi Predicting novel protein folds by using FRAGFOLD
    D T Jones
    Department of Biological Sciences, Brunel University, Uxbridge, Middlesex, United Kingdom
    Proteins . 2001
    ....
  11. ncbi Beta propellers: structural rigidity and functional diversity
    V Fulop
    Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    Curr Opin Struct Biol 9:715-21. 1999
    ..Possible strategies for identifying beta-propeller proteins in newly characterised sequences are helping to overcome the problems of predicting the beta-propeller fold from amino acid sequences...