Francis M Jiggins

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Sex-ratio-distorting Wolbachia causes sex-role reversal in its butterfly host
    F M Jiggins
    Department of Genetics, University of Cambridge, UK
    Proc Biol Sci 267:69-73. 2000
  2. ncbi How can sex ratio distorters reach extreme prevalences? Male-killing Wolbachia are not suppressed and have near-perfect vertical transmission efficiency in Acraea encedon
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Evolution 56:2290-5. 2002
  3. ncbi The rate of recombination in Wolbachia bacteria
    Francis M Jiggins
    Department of Genetics, University of Cambridge, UK
    Mol Biol Evol 19:1640-3. 2002
  4. ncbi Recent changes in phenotype and patterns of host specialization in Wolbachia bacteria
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, Department of Biology, University College London, 4 Stephenson Way, London, NW1 2HE, UK
    Mol Ecol 11:1275-83. 2002
  5. ncbi The evolution of parasite recognition genes in the innate immune system: purifying selection on Drosophila melanogaster peptidoglycan recognition proteins
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    J Mol Evol 57:598-605. 2003
  6. ncbi Recombination confounds interpretations of Wolbachia evolution
    F M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    Proc Biol Sci 268:1423-7. 2001
  7. ncbi Two male-killing Wolbachia strains coexist within a population of the butterfly Acraea encedon
    F M Jiggins
    Department of Genetics, Cambridge University, Downing Street, Cambridge, CB2 3EH, UK
    Heredity 86:161-6. 2001
  8. ncbi How many species are infected with Wolbachia? Cryptic sex ratio distorters revealed to be common by intensive sampling
    F M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    Proc Biol Sci 268:1123-6. 2001
  9. ncbi Male-killing Wolbachia and mitochondrial DNA: selective sweeps, hybrid introgression and parasite population dynamics
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom
    Genetics 164:5-12. 2003
  10. ncbi Problems with mitochondrial DNA as a marker in population, phylogeographic and phylogenetic studies: the effects of inherited symbionts
    Gregory D D Hurst
    Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK
    Proc Biol Sci 272:1525-34. 2005

Detail Information

Publications29

  1. ncbi Sex-ratio-distorting Wolbachia causes sex-role reversal in its butterfly host
    F M Jiggins
    Department of Genetics, University of Cambridge, UK
    Proc Biol Sci 267:69-73. 2000
    ..Female lekking swarms are absent from less female-biased populations and here the butterflies are instead associated with resources in the form of the larval food plant...
  2. ncbi How can sex ratio distorters reach extreme prevalences? Male-killing Wolbachia are not suppressed and have near-perfect vertical transmission efficiency in Acraea encedon
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Evolution 56:2290-5. 2002
    ..In conclusion, this male killer has spread to high prevalence because it has a high transmission efficiency and low cost, but the factors maintaining uninfected females in the population remain unknown...
  3. ncbi The rate of recombination in Wolbachia bacteria
    Francis M Jiggins
    Department of Genetics, University of Cambridge, UK
    Mol Biol Evol 19:1640-3. 2002
  4. ncbi Recent changes in phenotype and patterns of host specialization in Wolbachia bacteria
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, Department of Biology, University College London, 4 Stephenson Way, London, NW1 2HE, UK
    Mol Ecol 11:1275-83. 2002
    ..Therefore, we conclude that Wolbachia is most likely to move horizontally between closely related hosts, perhaps because of a combination of shared vectors for transmission and physiological specialization of the bacteria on those hosts...
  5. ncbi The evolution of parasite recognition genes in the innate immune system: purifying selection on Drosophila melanogaster peptidoglycan recognition proteins
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    J Mol Evol 57:598-605. 2003
    ..Therefore, interactions between these genes are unlikely to be the focus of host-parasite coevolution, at least in Drosophila. We also found evidence of gene conversion occurring between two genes, PGRP-SC1A and PGRP-SC1B...
  6. ncbi Recombination confounds interpretations of Wolbachia evolution
    F M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    Proc Biol Sci 268:1423-7. 2001
    ..Finally, we discuss the implications of recombination for attempts to genetically engineer Wolbachia for use in the control of crop pests and human pathogens...
  7. ncbi Two male-killing Wolbachia strains coexist within a population of the butterfly Acraea encedon
    F M Jiggins
    Department of Genetics, Cambridge University, Downing Street, Cambridge, CB2 3EH, UK
    Heredity 86:161-6. 2001
    ..Whether this polymorphism is stable, and what forces may be maintaining it, are unknown...
  8. ncbi How many species are infected with Wolbachia? Cryptic sex ratio distorters revealed to be common by intensive sampling
    F M Jiggins
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    Proc Biol Sci 268:1123-6. 2001
    ....
  9. ncbi Male-killing Wolbachia and mitochondrial DNA: selective sweeps, hybrid introgression and parasite population dynamics
    Francis M Jiggins
    Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, United Kingdom
    Genetics 164:5-12. 2003
    ..Instead, some other form of balancing selection may be maintaining uninfected females in the population and preventing the species from going extinct due to a shortage of males...
  10. ncbi Problems with mitochondrial DNA as a marker in population, phylogeographic and phylogenetic studies: the effects of inherited symbionts
    Gregory D D Hurst
    Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK
    Proc Biol Sci 272:1525-34. 2005
    ..We also discuss the impact of these studies on the current programme of taxonomy based on DNA bar-coding...
  11. ncbi Host-symbiont conflicts: positive selection on an outer membrane protein of parasitic but not mutualistic Rickettsiaceae
    Francis M Jiggins
    Department of Genetics, University of Cambridge, United Kingdom
    Mol Biol Evol 19:1341-9. 2002
    ..The regions of the wsp and map1 genes we identified as likely to be involved in host-parasite arms races should be examined in future studies of parasite virulence and host immune responses, and during the design of vaccines...
  12. ncbi Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication
    Michael M Magwire
    Department of Genetics, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 7:e1002337. 2011
    ....
  13. ncbi Melanic through nature or nurture: genetic polymorphism and phenotypic plasticity in Harmonia axyridis
    L J Michie
    Department of Genetics, University of Cambridge, Cambridge, UK
    J Evol Biol 23:1699-707. 2010
    ..As melanism is known to have a large effect on fitness in H. axyridis, this plasticity of melanization may have hastened its spread as an invasive species...
  14. ncbi Host-parasite coevolution: genetic variation in a virus population and the interaction with a host gene
    L Wilfert
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    J Evol Biol 23:1447-55. 2010
    ..Therefore, the high levels of genetic variation observed in this system do not appear to be maintained because of coevolution resulting from interactions between this host gene and parasite genes...
  15. ncbi What causes inefficient transmission of male-killing Wolbachia in Drosophila?
    G D Hurst
    Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK
    Heredity 87:220-6. 2001
    ..We suggest that the case of Wolbachia in D. bifasciata is one that is naturally balanced, the population being maintained polymorphic without the evolution of host resistance genes...
  16. ncbi The butterfly Danaus chrysippus is infected by a male-killing Spiroplasma bacterium
    F M Jiggins
    Department of Genetics, University of Cambridge, UK ac uk
    Parasitology 120:439-46. 2000
    ..Danaus chrysippus is a surprising host for a male-killer as its eggs are laid singly. This suggests that the ecological conditions permitting male-killers to invade may be more widespread than previously realized...
  17. ncbi Disease association mapping in Drosophila can be replicated in the wild
    Lena Wilfert
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    Biol Lett 6:666-8. 2010
    ..This genetic association is thus upheld in spite of a known genotype-by-genotype interaction and environmental variation...
  18. ncbi An ancient mitochondrial polymorphism in Adalis bipunctata linked to a sex-ratio-distorting bacterium
    Francis M Jiggins
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Genetics 171:1115-24. 2005
    ..We conclude that the fitness of these male killers may be negatively frequency dependent or different strains may be favored in different populations. These hypotheses await experimental confirmation...
  19. ncbi The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae
    Darren J Obbard
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Rd, Edinburgh EH9 3JT, UK
    BMC Evol Biol 8:274. 2008
    ..We studied whether TEP1 is a case of an ancient balanced polymorphism in an animal immune system...
  20. ncbi Genetic variation affecting host-parasite interactions: major-effect quantitative trait loci affect the transmission of sigma virus in Drosophila melanogaster
    Jenny Bangham
    School of Biological Sciences, Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, The King s Buildings, West Mains Road, Edinburgh, UK
    Mol Ecol 17:3800-7. 2008
    ..Our data, together with previous experiments on the sigma virus and parasitoid wasps, indicate that the resistance of D. melanogaster to co-evolved pathogens is controlled by a limited number of major-effect polymorphisms...
  21. ncbi Are we underestimating the diversity and incidence of insect bacterial symbionts? A case study in ladybird beetles
    Lucy A Weinert
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3JT, UK
    Biol Lett 3:678-81. 2007
    ..Our results suggest that the true incidence and diversity of bacterial symbionts in insects may be far greater than previously thought...
  22. ncbi The recent spread of a vertically transmitted virus through populations of Drosophila melanogaster
    Jennifer A Carpenter
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3JT, Scotland, UK
    Mol Ecol 16:3947-54. 2007
    ..This is surprising for a vertically transmitted pathogen that has a similar migration rate to its host. We suggest that the low structure in the viral populations can be explained by the smaller effective population size of the virus...
  23. ncbi The age and evolution of an antiviral resistance mutation in Drosophila melanogaster
    Jenny Bangham
    School of Biological Sciences, Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, The King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
    Proc Biol Sci 274:2027-34. 2007
    ..We find that the ref(2)P resistance mutation is considerably older than the recent spread of this viral strain and suggest that--possibly because it is recessive--the initial spread of the resistance mutation was very slow...
  24. ncbi Contrasting evolutionary patterns in Drosophila immune receptors
    Francis M Jiggins
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, Scotland
    J Mol Evol 63:769-80. 2006
    ..In contrast to the Tep genes, the GNBP genes are highly conserved. We discuss the reasons why different components of the immune system have such different patterns of evolution...
  25. ncbi Natural selection drives extremely rapid evolution in antiviral RNAi genes
    Darren J Obbard
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, United Kingdom
    Curr Biol 16:580-5. 2006
    ..This is a signature of host-pathogen arms races and implies that the ancient battle between RNA viruses and host antiviral RNAi genes is active and significant in shaping RNAi function...
  26. ncbi Adaptive evolution and recombination of Rickettsia antigens
    Francis M Jiggins
    Institute of Cell Animal and Population Biology, Ashworth Laboratories, School of Biology, University of Edinburgh, The King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
    J Mol Evol 62:99-110. 2006
    ..However, recombination has been sufficiently infrequent that the phylogenies of the three genes are similar, although not identical...
  27. ncbi The evolution of antifungal peptides in Drosophila
    Francis M Jiggins
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Ashworth Lab, King s Buildings, West Mains Road, Edinburgh EH9 3JT, Scotland
    Genetics 171:1847-59. 2005
    ..This can be explained if both upstream and nonsynonymous mutations are slightly deleterious and are removed more effectively from D. simulans due to its larger effective population size...
  28. ncbi Genetic variation affecting host-parasite interactions: different genes affect different aspects of sigma virus replication and transmission in Drosophila melanogaster
    Jenny Bangham
    School of Biological Sciences, Institute of Evolutionary Biology, The University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Genetics 178:2191-9. 2008
    ..This suggests that different loci affect viral replication and paternal transmission...
  29. ncbi The effect of Wolbachia-induced cytoplasmic incompatibility on host population size in natural and manipulated systems
    Stephen L Dobson
    Department of Entomology, University of Kentucky, S225 Agricultural Science Center North, Lexington, KY 40546 0091, USA
    Proc Biol Sci 269:437-45. 2002
    ....