Research Topics
| M D JenkinsonSummaryAffiliation: University of Liverpool Country: UK Publications
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Detail Information
Publications
Advanced MRI in the management of adult gliomasM D Jenkinson
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, University of Liverpool, UK
Br J Neurosurg 21:550-61. 2007..These newer techniques have been adopted with varying success in the management of adult gliomas. This review focuses on the application of advanced MR imaging in the clinical management of adult gliomas...- Cerebral blood volume, genotype and chemosensitivity in oligodendroglial tumoursMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Liverpool, UK
Neuroradiology 48:703-13. 2006..CONCLUSION: rCBV identifies oligodendroglial tumours with 1p/19q loss, but does not predict chemosensitivity. The prognostic significance of rCBV may differ in oligodendroglial tumours with or without the -1p/-19q genotype... - The role of temozolomide in newly-diagnosed glioblastoma multiformeMichael D Jenkinson
The Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerly, Liverpool, UK
Br J Neurosurg 22:456. 2008 - Spinal cord tracts and clinical correlatesM D Jenkinson
Walton Centre for Neurology and Neurosurgery, Liverpool, UK
Br J Neurosurg 22:710-2. 2008..The spinal cord tracts and common clinical presentations are tested along with spinal cord vasculature... - The role of endoscopic third ventriculostomy in adult patients with hydrocephalusMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Liverpool, L9 7LJ, United Kingdom
J Neurosurg 110:861-6. 2009..The role of ETV in adult patients with hydrocephalus was therefore investigated... - Cellularity and apparent diffusion coefficient in oligodendroglial tumours characterized by genotypeMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool, L9 7LJ, UK
J Neurooncol 96:385-92. 2010..This study evaluated the relationship between ADC and tumour cellularity in oligodendroglial tumours characterized by genotype... - Phase II trial of intratumoral BCNU injection and radiotherapy on untreated adult malignant gliomaMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
J Neurooncol 99:103-13. 2010..The imaging data forms a biological basis for understanding the effects of high dose BCNU delivered intratumorally by SFP, and suggests early effects on tumour vasculature and metabolism... - Molecular genetics, imaging and treatment of oligodendroglial tumoursMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool, L9 7LJ, UK
Acta Neurochir (Wien) 152:1815-25. 2010.... - Cognitive and functional outcome in spina bifida-Chiari II malformationMichael D Jenkinson
Department of Neurosurgery, The Walton Centre Foundation NHS Trust, Lower Lane, Liverpool, L9 7LJ, UK
Childs Nerv Syst 27:967-74. 2011..Neuropsychological testing is increasingly important in outcome assessment. We investigated the health, disability, lifestyle and cognitive function in adults who had myelomeningocoele closure at birth... - Management of cerebral metastasis: evidence-based approach for surgery, stereotactic radiosurgery and radiotherapyMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool, L9 7LJ, UK
Eur J Cancer 47:649-55. 2011..In long-term survivors WBRT may cause cognitive decline and SRS is being explored as an alternative method of disease control. Increasingly, quality of life and neuro-cognitive function are being used as end-points in clinical trials... - Apparent diffusion coefficients in oligodendroglial tumors characterized by genotypeMichael D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Liverpool, UK
J Magn Reson Imaging 26:1405-12. 2007..Oligodendroglial tumors with or without 1p/19q loss differ in their therapeutic responsiveness and prognosis, and recent reports also suggest that these tumors may differ in their magnetic resonance characteristics and blood volume... - MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypesM D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Liverpool, UK
Neurology 64:2085-9. 2005..Oligodendroglial neoplasms with combined loss of chromosomes 1p and 19q may have a good prognosis and respond to procarbazine-lomustine (CCNU)-vincristine (PCV) chemotherapy... - Histological growth patterns and genotype in oligodendroglial tumours: correlation with MRI featuresMichael D Jenkinson
Departments of Neurosurgery, University of Liverpool Liverpool, UK
Brain 129:1884-91. 2006..This study identified a group of oligodendroglial tumours with intact 1p/19q displaying distinctive MR imaging features that were unrelated to the histopathology characteristics... - Outcome predictors and complications in the management of intradural spinal tumoursM D Jenkinson
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
Eur Spine J 15:203-10. 2006..Pre-operative functional status was a predictor of good post-operative function for intra- and extramedullary tumours and for intramedullary tumours a good post-operative Frankel score predicted long-term survival... - Cerebral aneurysm associated with an intracranial tumour: staged endovascular and surgical treatment in two casesM Javadpour
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
Br J Neurosurg 18:280-4. 2004..Endovascular techniques can be employed to make the surgical excision of an intracranial tumour co-existing with an incidental aneurysm safer... - Vanishing contrast enhancement in malignant glioma after corticosteroid treatmentH S Zaki
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, UK
Acta Neurochir (Wien) 146:841-5. 2004.... - 'Recurrent' glioblastoma multiforme, when should we reoperate?Giuseppe M V Barbagallo
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerly, Liverpool, UK
Br J Neurosurg 22:452-5. 2008..Surgical treatment of recurrent glioblastoma multiforme in selected patients should always be considered... - Intracerebral abscess formation following embolisation of an internal carotid artery aneurysm using Guglielmi detachable coilsM D Jenkinson
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
Acta Neurochir (Wien) 145:703-5; discussion 705-6. 2003..The abscess was successfully treated by antibiotic therapy. Infected Guglielmi detachable coils (GDC) may result in abscess formation in the presence of underlying cerebral ischaemia... - Synchronous basal cell carcinoma and meningioma following cranial irradiation for a pilocytic astrocytomaM D Jenkinson
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
Br J Neurosurg 17:182-4. 2003..Synchronous radiation-induced tumours are a rare occurrence... - Impact of brain biopsy on the management of patients with nonneoplastic undiagnosed neurological disordersHeinke Pulhorn
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
Neurosurgery 62:833-7; discussion 837-8. 2008.... - Outcome predictors in the management of spinal cord ependymomaD Gavin Quigley
Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
Eur Spine J 16:399-404. 2007..006). Extent of resection and the use of adjuvant radiotherapy did not influence PFS or OS; however, early diagnosis and treatment are paramount in the management of spinal ependymoma if a good functional outcome is to be achieved... - Correlation of molecular genetics with molecular and morphological imaging in gliomas with an oligodendroglial componentCarol Walker
JK Douglas Laboratories and Clatterbridge Centre for Oncology, Clatterbridge Hospital, Bebington, Wirral, United Kingdom
Clin Cancer Res 10:7182-91. 2004..Histopathology diagnosis remains challenging and new tools such as molecular genetics or molecular imaging require evaluation...