Dafyd J Jenkins

Summary

Affiliation: University of Warwick

Country: UK

De novo evolution of complex, global and hierarchical gene regulatory mechanisms
Dafyd J Jenkins
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
J Mol Evol 71:128-40. 2010
A new model for investigating the evolution of transcription control networks
Dafyd J Jenkins
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, UK
Artif Life 15:259-91. 2009
Strong negative self regulation of prokaryotic transcription factors increases the intrinsic noise of protein expression
Dov J Stekel
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston B15 2TT, UK
BMC Syst Biol 2:6. 2008

De novo evolution of complex, global and hierarchical gene regulatory mechanisms
Dafyd J Jenkins
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
J Mol Evol 71:128-40. 2010
..These results highlight the adaptive and incremental evolution of complex biological networks, and the value and potential of studying realistic in silico evolutionary systems as a way of understanding living systems...
A new model for investigating the evolution of transcription control networks
Dafyd J Jenkins
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, UK
Artif Life 15:259-91. 2009
..This study also highlights the importance of using in silico genetics techniques to investigate evolved model robustness...
Strong negative self regulation of prokaryotic transcription factors increases the intrinsic noise of protein expression
Dov J Stekel
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston B15 2TT, UK
BMC Syst Biol 2:6. 2008
..We explore the role of negative self regulation of transcription in regulating the variability of protein abundance using a variety of stochastic modeling techniques...