Ashraf E K Ibrahim

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi MMASS: an optimized array-based method for assessing CpG island methylation
    Ashraf E K Ibrahim
    Department of Pathology, Division of Molecular Histopathology, Addenbrooke s Hospital Hills Road, Cambridge CB2 2XZ, UK
    Nucleic Acids Res 34:e136. 2006
  2. ncbi Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression
    Ashraf E K Ibrahim
    Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, UK
    Gut 60:499-508. 2011
  3. ncbi Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer
    Yoko Ito
    Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Hum Mol Genet 17:2633-43. 2008
  4. ncbi High-throughput methylation profiling by MCA coupled to CpG island microarray
    Marcos R H Estecio
    Department of Leukemia, UT M D Anderson Cancer Center, Houston, Texas 77030, USA
    Genome Res 17:1529-36. 2007
  5. ncbi The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel
    Ahmed Ashour Ahmed
    Functional Genomics of Drug Resistance Laboratory, Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Cancer Cell 12:514-27. 2007

Collaborators

Detail Information

Publications5

  1. ncbi MMASS: an optimized array-based method for assessing CpG island methylation
    Ashraf E K Ibrahim
    Department of Pathology, Division of Molecular Histopathology, Addenbrooke s Hospital Hills Road, Cambridge CB2 2XZ, UK
    Nucleic Acids Res 34:e136. 2006
    ..The MMASS-v2 method offers improved sensitivity and statistical power for high-throughput microarray identification of differential methylation...
  2. ncbi Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression
    Ashraf E K Ibrahim
    Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, UK
    Gut 60:499-508. 2011
    ....
  3. ncbi Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer
    Yoko Ito
    Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Hum Mol Genet 17:2633-43. 2008
    ..These results indicate that IGF2 DMR0 hypomethylation has diagnostic potential for colon cancer rather than value as a surrogate biomarker for constitutive LOI...
  4. ncbi High-throughput methylation profiling by MCA coupled to CpG island microarray
    Marcos R H Estecio
    Department of Leukemia, UT M D Anderson Cancer Center, Houston, Texas 77030, USA
    Genome Res 17:1529-36. 2007
    ..In summary, MCAM is a suitable technique to discover methylated genes and to profile methylation changes in clinical samples in a high-throughput fashion...
  5. ncbi The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel
    Ahmed Ashour Ahmed
    Functional Genomics of Drug Resistance Laboratory, Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Cancer Cell 12:514-27. 2007
    ..These data show that ECM can mediate taxane sensitivity by modulating microtubule stability...