Maj A Hultén

Summary

Affiliation: University of Warwick
Country: UK

Publications

  1. ncbi Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCR
    Maj A Hultén
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Reproduction 126:279-97. 2003
  2. ncbi On the origin of trisomy 21 Down syndrome
    Maj A Hultén
    Warwick Medical School, University of Warwick, UK
    Mol Cytogenet 1:21. 2008
  3. ncbi On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model
    Maj A Hultén
    Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    Reproduction 139:1-9. 2010
  4. ncbi On the paternal origin of trisomy 21 Down syndrome
    Maj A Hultén
    Warwick Medical School, University of Warwick, UK
    Mol Cytogenet 3:4. 2010
  5. ncbi On the origin of crossover interference: A chromosome oscillatory movement (COM) model
    Maj A Hultén
    Department of Molecular Medicine and Surgery and Center for Molecular Medicine, CMM L8 02, Karolinska Institutet, Karolinska University Hospital, Solna, S 17 1 76 Stockholm, Sweden
    Mol Cytogenet 4:10. 2011
  6. ncbi Germinal and Somatic Trisomy 21 Mosaicism: How Common is it, What are the Implications for Individual Carriers and How Does it Come About?
    Maj A Hultén
    Warwick Medical School, University of Warwick, UK
    Curr Genomics 11:409-19. 2010
  7. ncbi Patterns of meiotic recombination in human fetal oocytes
    Charles Tease
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
    Am J Hum Genet 70:1469-79. 2002

Detail Information

Publications7

  1. ncbi Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCR
    Maj A Hultén
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Reproduction 126:279-97. 2003
    ..The implication, on the other hand, is that around one in 500 to one in 1000 cases with a mentally and/or physically disabling chromosome disorder would remain undiagnosed...
  2. ncbi On the origin of trisomy 21 Down syndrome
    Maj A Hultén
    Warwick Medical School, University of Warwick, UK
    Mol Cytogenet 1:21. 2008
    ..In spite of intensive efforts to understand the underlying reason(s) for these characteristics, the origin still remains unknown. We hypothesize that maternal trisomy 21 ovarian mosaicism might provide the major causative factor...
  3. ncbi On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model
    Maj A Hultén
    Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    Reproduction 139:1-9. 2010
    ....
  4. ncbi On the paternal origin of trisomy 21 Down syndrome
    Maj A Hultén
    Warwick Medical School, University of Warwick, UK
    Mol Cytogenet 3:4. 2010
    ..e. in less than 10% of T21 DS cases. We here report data indicating that one reason for this parental sex difference is a very much lower degree of fetal testicular in comparison to ovarian T21 mosaicism...
  5. ncbi On the origin of crossover interference: A chromosome oscillatory movement (COM) model
    Maj A Hultén
    Department of Molecular Medicine and Surgery and Center for Molecular Medicine, CMM L8 02, Karolinska Institutet, Karolinska University Hospital, Solna, S 17 1 76 Stockholm, Sweden
    Mol Cytogenet 4:10. 2011
    ..abstract:..
  6. ncbi Germinal and Somatic Trisomy 21 Mosaicism: How Common is it, What are the Implications for Individual Carriers and How Does it Come About?
    Maj A Hultén
    Warwick Medical School, University of Warwick, UK
    Curr Genomics 11:409-19. 2010
    ....
  7. ncbi Patterns of meiotic recombination in human fetal oocytes
    Charles Tease
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
    Am J Hum Genet 70:1469-79. 2002
    ..We speculate that these abnormal fetal oocytes may be the source of the nonrecombinant chromosomes 13 and X suggested, by genetic studies, to be associated with maternally derived chromosome nondisjunction...