Gareth J Hughes

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi Virus immunocapture provides evidence of CD8 lymphocyte-derived HIV-1 in vivo
    Gareth J Hughes
    Centre for Infectious Diseases, University of Edinburgh, Summerhall, Edinburgh, UK
    AIDS 21:1507-13. 2007
  2. ncbi HIV-1-infected CD8+CD4+ T cells decay in vivo at a similar rate to infected CD4 T cells during HAART
    Gareth J Hughes
    Centre for Infectious Diseases, University of Edinburgh, Edinburgh, UK
    AIDS 22:57-65. 2008
  3. ncbi A reassessment of the emergence time of European bat lyssavirus type 1
    Gareth J Hughes
    Institute of Evolutionary Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Infect Genet Evol 8:820-4. 2008
  4. ncbi Transmission network parameters estimated from HIV sequences for a nationwide epidemic
    Andrew J Leigh Brown
    Institute of Evolutionary Biology, University of Edinburgh, London, United Kingdom
    J Infect Dis 204:1463-9. 2011
  5. ncbi Molecular phylodynamics of the heterosexual HIV epidemic in the United Kingdom
    Gareth J Hughes
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS Pathog 5:e1000590. 2009
  6. ncbi Episodic sexual transmission of HIV revealed by molecular phylodynamics
    Fraser Lewis
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland
    PLoS Med 5:e50. 2008

Detail Information

Publications6

  1. ncbi Virus immunocapture provides evidence of CD8 lymphocyte-derived HIV-1 in vivo
    Gareth J Hughes
    Centre for Infectious Diseases, University of Edinburgh, Summerhall, Edinburgh, UK
    AIDS 21:1507-13. 2007
    ....
  2. ncbi HIV-1-infected CD8+CD4+ T cells decay in vivo at a similar rate to infected CD4 T cells during HAART
    Gareth J Hughes
    Centre for Infectious Diseases, University of Edinburgh, Edinburgh, UK
    AIDS 22:57-65. 2008
    ..To investigate the potential for CD4+CD8+ T cells [CD8 double positive (CD8 DP)] T cells to form a reservoir of HIV-1 following HAART through measurement of the rate of decay of infected CD4/CD8 DP T cells...
  3. ncbi A reassessment of the emergence time of European bat lyssavirus type 1
    Gareth J Hughes
    Institute of Evolutionary Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Infect Genet Evol 8:820-4. 2008
    ..Reconstruction of the population histories suggests that EBLV-1B may be emerging whilst the signal derived from the EBLV-1A phylogeny may be dampened by clade-specific dynamics...
  4. ncbi Transmission network parameters estimated from HIV sequences for a nationwide epidemic
    Andrew J Leigh Brown
    Institute of Evolutionary Biology, University of Edinburgh, London, United Kingdom
    J Infect Dis 204:1463-9. 2011
    ..Recent developments in molecular phylodynamics have provided new routes to obtain these parameter estimates, and current clinical practice provides suitable data for entire infected populations...
  5. ncbi Molecular phylodynamics of the heterosexual HIV epidemic in the United Kingdom
    Gareth J Hughes
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS Pathog 5:e1000590. 2009
    ..More effective intervention to restrict the epidemic may therefore be feasible, given effective diagnosis programmes...
  6. ncbi Episodic sexual transmission of HIV revealed by molecular phylodynamics
    Fraser Lewis
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland
    PLoS Med 5:e50. 2008
    ..The aim of this study was to analyze a high-density sample of an HIV-infected population using recently developed techniques in phylogenetics to infer the short-term dynamics of the epidemic among men who have sex with men (MSM)...