Humphrey Hodgson

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Hormonal therapy for gastrointestinal angiodysplasia
    Humphrey Hodgson
    Department of Medicine, Royal Free and University College School of Medicine, London, UK
    Lancet 359:1630-1. 2002
  2. ncbi Sheila Sherlock's legacy
    Humphrey Hodgson
    Department of Medicine, Royal Free and University College School of Medicine, NW3 2PF, London, UK
    Lancet 359:460. 2002
  3. ncbi Growth factors improve gene expression after lentiviral transduction in human adult and fetal hepatocytes
    Clare Selden
    Department of Medicine, UCL Centre for Hepatology, Royal Free Hampstead Campus, Royal Free and University College Medical School, Rowland Hill Street, Hampstead, London NW3 2PF, UK
    J Gene Med 9:67-76. 2007
  4. ncbi During thioacetamide-induced acute liver failure, the proliferative response of hepatocytes to thyroid hormone is maintained, indicating a potential therapeutic approach to toxin-induced liver disease
    Raza Malik
    Centre for Hepatology, Department of Medicine, Royal Free Campus, Royal Free and University College Medical School, Rowland Hill Street, Hampstead, London, United Kingdom, NW3 2PF
    Dig Dis Sci 51:2235-41. 2006
  5. ncbi Ischemic preconditioning impairs liver regeneration in extended reduced-size livers
    Mohammed M Habib
    Ann Surg 244:328-9; author reply 329-30. 2006
  6. ncbi Co-transplantation of encapsulated HepG2 and rat Sertoli cells improves outcome in a thioacetamide induced rat model of acute hepatic failure
    Tony Manibur Rahman
    Department of Medicine, Centre for Hepatology, Royal Free and University College Medical School, Hampstead, London, NW3 2PF, UK
    Transpl Int 18:1001-9. 2005
  7. ncbi Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis
    Peter Collins
    Centre for Hepatology, Department of Medicine, Royal Free and University College Medical School, London, UK
    Liver Int 25:880-7. 2005
  8. ncbi Exogenous thyroid hormone induces liver enlargement, whilst maintaining regenerative potential--a study relevant to donor preconditioning
    Raza Malik
    Centre for Hepatology, Department of Medicine, Royal Free Campus, Royal Free and University College Medical School, Hampstead, London NW3 2PF, UK
    Am J Transplant 5:1801-7. 2005
  9. ncbi Cellular therapies for liver replacement
    Clare Selden
    Centre for Hepatology, Royal Free Campus, Royal Free and University College Medical School, London NW3 2PF, UK
    Transpl Immunol 12:273-88. 2004
  10. ncbi Liver cells: biology to therapeutics
    Humphrey Hodgson
    Royal Free and University College Medical School, London
    Clin Med 3:161-5. 2003

Collaborators

  • Clare Selden
  • Raza Malik
  • K-T Khaw
  • Peter Collins
  • David J Leaper
  • R Horton
  • Myrddin Rees
  • Morris Brown
  • John Gibson
  • Ashley Grossman
  • George Hart
  • Roy Taylor
  • John Monson
  • Hugh Watkins
  • John Camm
  • Brian Rowlands
  • Tony Heagerty
  • Nick Boon
  • Rebecca Saich
  • Mark Caulfield
  • Alistair Hall
  • George Griffin
  • Edwin Chilvers
  • Nick Brooks
  • Nick Wright
  • Philip Home
  • John Lazarus
  • Robert Sutton
  • Richard Hughes
  • Mohammed M Habib
  • Tony Manibur Rahman
  • Neil Scolding
  • Pamela Ewan
  • Julian Scott
  • Peter McCollum
  • Paul Corris
  • Edwina Brown
  • Brian R Davidson
  • Ivan Diakanov

Detail Information

Publications16

  1. ncbi Hormonal therapy for gastrointestinal angiodysplasia
    Humphrey Hodgson
    Department of Medicine, Royal Free and University College School of Medicine, London, UK
    Lancet 359:1630-1. 2002
  2. ncbi Sheila Sherlock's legacy
    Humphrey Hodgson
    Department of Medicine, Royal Free and University College School of Medicine, NW3 2PF, London, UK
    Lancet 359:460. 2002
  3. ncbi Growth factors improve gene expression after lentiviral transduction in human adult and fetal hepatocytes
    Clare Selden
    Department of Medicine, UCL Centre for Hepatology, Royal Free Hampstead Campus, Royal Free and University College Medical School, Rowland Hill Street, Hampstead, London NW3 2PF, UK
    J Gene Med 9:67-76. 2007
    ..However, transduction approaches which reduce the multiplicities of infection (MOIs) required provide potential benefit of cost and safety for therapeutic use...
  4. ncbi During thioacetamide-induced acute liver failure, the proliferative response of hepatocytes to thyroid hormone is maintained, indicating a potential therapeutic approach to toxin-induced liver disease
    Raza Malik
    Centre for Hepatology, Department of Medicine, Royal Free Campus, Royal Free and University College Medical School, Rowland Hill Street, Hampstead, London, United Kingdom, NW3 2PF
    Dig Dis Sci 51:2235-41. 2006
    ..We conclude that the ability of hepatocytes in the midzonal areas of rat liver to proliferate in response to tri-iodothyonine is maintained during severe acute toxic injury...
  5. ncbi Ischemic preconditioning impairs liver regeneration in extended reduced-size livers
    Mohammed M Habib
    Ann Surg 244:328-9; author reply 329-30. 2006
  6. ncbi Co-transplantation of encapsulated HepG2 and rat Sertoli cells improves outcome in a thioacetamide induced rat model of acute hepatic failure
    Tony Manibur Rahman
    Department of Medicine, Centre for Hepatology, Royal Free and University College Medical School, Hampstead, London, NW3 2PF, UK
    Transpl Int 18:1001-9. 2005
    ..Combined encapsulation and locally generated immuno-suppression may be a valuable strategy in hepatocyte transplantation...
  7. ncbi Increased expression of uncoupling protein 2 in HepG2 cells attenuates oxidative damage and apoptosis
    Peter Collins
    Centre for Hepatology, Department of Medicine, Royal Free and University College Medical School, London, UK
    Liver Int 25:880-7. 2005
    ..Oxidative damage plays a major part in the pathogenesis of liver disease. Uncoupling proteins (UCPs) may be able to limit the generation of reactive oxygen species (ROS) and be cytoprotective...
  8. ncbi Exogenous thyroid hormone induces liver enlargement, whilst maintaining regenerative potential--a study relevant to donor preconditioning
    Raza Malik
    Centre for Hepatology, Department of Medicine, Royal Free Campus, Royal Free and University College Medical School, Hampstead, London NW3 2PF, UK
    Am J Transplant 5:1801-7. 2005
    ..Using more stringent conditions to test hepatic functional reserve, following 90% hepatectomy, there was a greater (57%) survival in animals pre-treated with T3 compared to 14% in controls...
  9. ncbi Cellular therapies for liver replacement
    Clare Selden
    Centre for Hepatology, Royal Free Campus, Royal Free and University College Medical School, London NW3 2PF, UK
    Transpl Immunol 12:273-88. 2004
    ..The use of cells derived from stem cells or foetal rather than adult liver cells is also emerging as a potential human cell source which may overcome problems associated with xenogeneic cells...
  10. ncbi Liver cells: biology to therapeutics
    Humphrey Hodgson
    Royal Free and University College Medical School, London
    Clin Med 3:161-5. 2003
    ....
  11. ncbi Triiodothyronine enhances the regenerative capacity of the liver following partial hepatectomy
    Raza Malik
    Centre for Hepatology, Department of Medicine, Royal Free Campus, Royal Free and University College Medical School, Hampstead, London, England
    Hepatology 37:79-86. 2003
    ..The ability to enhance cell proliferation during compensatory hyperplasia following PH could be therapeutically valuable if applicable to humans...
  12. ncbi The role of non-parenchymal cells in liver growth
    Raza Malik
    Centre for Hepatology, Royal Free and University College Medical School, Rowland Hill Street, Hampstead, NW3 2PF, London, UK
    Semin Cell Dev Biol 13:425-31. 2002
    ....
  13. ncbi A statement by The Royal Free and University College Medical School and The Royal Free Hampstead NHS Trust
    Humphrey Hodgson
    Lancet 363:824. 2004
  14. ncbi Modernising medical careers, medical training application service, and the postgraduate medical education and training board: time for the emperors to don their clothes
    Morris Brown
    University of Cambridge, Cambridge CB2 2QQ, UK
    Lancet 369:967-8. 2007
  15. ncbi Medical training in the UK: sleepwalking to disaster
    Morris Brown
    University of Cambridge, Cambridge CB2 2QQ, UK
    Lancet 369:1673-5. 2007
  16. ncbi Characterization of pro-apoptotic effect of liver failure plasma on primary human hepatocytes and its modulation by molecular adsorbent recirculation system therapy
    Rebecca Saich
    Centre for Hepatology, Department of Medicine, Royal Free and University College Medical School, Hampstead Campus, London, UK
    Artif Organs 31:732-42. 2007
    ..The apoptosis induced in the presence of liver failure plasma was not reduced by MARS dialysis...