Research Topics
Species | W L HallSummaryAffiliation: University of Reading Country: UK Publications
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Publications
Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol productionWendy L Hall
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, United Kingdom
Am J Clin Nutr 82:1260-8; quiz 1365-6. 2005..The reduction of concentrations of circulating inflammatory markers by estrogen may be one of the mechanisms by which premenopausal women are protected against cardiovascular disease...
Physiological mechanisms mediating aspartame-induced satietyW L Hall
Centre for Nutrition and Food Safety, School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
Physiol Behav 78:557-62. 2003..9774, P=.004). In conclusion, it is unlikely that aspartame increases satiety via CCK- or GLP-1-mediated mechanisms, but small changes in circulating phenylalanine concentrations may influence appetite...
Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetiteW L Hall
Centre for Nutrition and Food Safety, School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 7XH
Br J Nutr 89:239-48. 2003....
Metabolic syndrome: what is it and what are the implications?D I Shaw
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading RG6 6AP, UK
Proc Nutr Soc 64:349-57. 2005..The LIPGENE project will investigate dietary fat quality as a strategy for the prevention of metabolic syndrome and identify food chain approaches that can support consumer attempts to alter their dietary patterns...
A high-fat meal enriched with eicosapentaenoic acid reduces postprandial arterial stiffness measured by digital volume pulse analysis in healthy menWendy L Hall
Nutritional Sciences Division, School of Biomedical and Health Sciences, King s College London, London SE1 7EH UK
J Nutr 138:287-91. 2008..Changes in other variables measured also did not differ after subjects consumed the 2 meals. In conclusion, adding EPA to a high-fat meal results in acute changes in vascular tone, independent of changes in oxidative stress...
A meal enriched with soy isoflavones increases nitric oxide-mediated vasodilation in healthy postmenopausal womenWendy L Hall
Nutritional Sciences Division, School of Biomedical and Health Sciences, King s College London, London SE1 9NH, UK
J Nutr 138:1288-92. 2008..In conclusion, consuming an isoflavone-enriched low-fat meal acutely increases endothelium-dependent vasodilation in postmenopausal women. Regular consumption of soy isoflavones may protect against endothelial dysfunction...
Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavonesDagmar Fuchs
Department of Food and Nutrition, Molecular Nutrition Unit, Technical University of Munich, Freising, Federal Republic of Germany
Am J Clin Nutr 86:1369-75. 2007..The incidence of cardiovascular diseases increases after menopause, and soy consumption is suggested to inhibit disease development...
Comparative effects of fatty acids on endothelial inflammatory gene expressionDanielle I Shaw
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, RG6 6AP, UK
Eur J Nutr 46:321-8. 2007..Although in vitro studies have failed to show consistent findings, this may reflect the diverse experimental protocols employed and the limited range of FAs and end points studied...
Dietary isoflavones in the prevention of cardiovascular disease--a molecular perspectiveGerald Rimbach
Institute of Human Nutrition and Food Science, Christian Albrechts University Kiel, Hermann Rodewald Strasse 6, D 24118 Kiel, Germany
Food Chem Toxicol 46:1308-19. 2008..Nutrigenetic effects of this type have recently been reported for dietary isoflavones, and may help to explain some of the disparities in the current literature concerning isoflavones and cardiovascular health...
Soy isoflavones increase preprandial peptide YY (PYY), but have no effect on ghrelin and body weight in healthy postmenopausal womenMartin O Weickert
German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
J Negat Results Biomed 5:11. 2006..Seventeen of the subjects were classified as equol producers. Plasma concentrations of ghrelin and PYY, as well as energy intake and body weight were measured at baseline and after four and eight weeks of each intervention arm...
Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged menSabine Tricon
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences and the School of Animal and Microbial Sciences, The University of Reading, Whiteknights, Reading RG6 6AP, United Kingdom
Am J Clin Nutr 83:744-53. 2006..However, feeding regimens that enhance the CLA content of milk also increase concentrations of trans-18:1 fatty acids. The implications for human health are not yet known...
Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol productionWendy L Hall
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, United Kingdom
Am J Clin Nutr 83:592-600. 2006..However, beneficial effects of isolated isoflavones on lipid biomarkers of cardiovascular disease risk have not yet been shown...
Does genotype and equol-production status affect response to isoflavones? Data from a pan-European study on the effects of isoflavones on cardiovascular risk markers in post-menopausal womenKaterina Vafeiadou
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, Whiteknights, University of Reading, UK
Proc Nutr Soc 65:106-15. 2006..In conclusion, isoflavones have beneficial effects on C-reactive protein, but not other cardiovascular risk markers. However, specific ERbeta gene polymorphic subgroups may benefit from isoflavone supplementation...
Consumption of soy isoflavones does not affect plasma total homocysteine or asymmetric dimethylarginine concentrations in healthy postmenopausal womenManja Reimann
German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
J Nutr 136:100-5. 2006..Changes from baseline in plasma ADMA and folate were negatively correlated (r = -0.18, P = 0.017). These results challenge the overall health effect of isoflavone supplementation in healthy postmenopausal women...
Physiological factors influencing vitamin E biokineticsJohn K Lodge
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom
Ann N Y Acad Sci 1031:60-73. 2004..Taken together, these data show that several physiological factors influence the uptake of newly absorbed alpha-tocopherol, and that this is an important consideration in the design of future vitamin E supplementation studies...
The absorption of vitamin E is influenced by the amount of fat in a meal and the food matrixYvonne M Jeanes
Centre for Nutrition and Food Safety, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
Br J Nutr 92:575-9. 2004..These results demonstrate that both the amount of fat and the food matrix influence vitamin E absorption. These factors should be considered by consumers and for future vitamin E intervention studies...
Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trialsLee Hooper
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, United Kingdom
Am J Clin Nutr 88:38-50. 2008..The beneficial effects of flavonoid consumption on cardiovascular risk are supported by mechanistic and epidemiologic evidence...
