G Gregoriadis

Summary

Affiliation: University of London
Country: UK

Publications

  1. ncbi Liposome-mediated DNA vaccination
    G Gregoriadis
    The School of Pharmacy, University of London, UK
    FEBS Lett 402:107-10. 1997
  2. ncbi Genetic vaccines: strategies for optimization
    G Gregoriadis
    Centre for Drug Delivery Research, The School of Pharmacy, London, UK
    Pharm Res 15:661-70. 1998
  3. ncbi Vaccine entrapment in liposomes
    G Gregoriadis
    The School of Pharmacy, University of London, 29 39 Brunswick Square, London, WC1N 1AX, United Kingdom
    Methods 19:156-62. 1999
  4. ncbi Polysialic acids: potential in improving the stability and pharmacokinetics of proteins and other therapeutics
    G Gregoriadis
    Centre for Drug Delivery Research School of Pharmacy, University of London, United Kingdom
    Cell Mol Life Sci 57:1964-9. 2000
  5. ncbi DNA vaccines: a role for liposomes
    G Gregoriadis
    Centre for Drug Delivery Research, School of Pharmacy, University of London, 29 39 Brunswick Square, London, WCIN 1AX, UK
    Curr Opin Mol Ther 1:39-42. 1999
  6. ncbi Liposome-mediated DNA vaccination: the effect of vesicle composition
    Y Perrie
    Centre for Drug Delivery Research, The School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, UK
    Vaccine 19:3301-10. 2001
  7. ncbi The effect of polysialylation on the immunogenicity and antigenicity of asparaginase: implication in its pharmacokinetics
    A I Fernandes
    Centre for Drug Delivery Research, School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, UK
    Int J Pharm 217:215-24. 2001

Collaborators

  • A I Fernandes
  • Y Perrie
  • P M Frederik

Detail Information

Publications7

  1. ncbi Liposome-mediated DNA vaccination
    G Gregoriadis
    The School of Pharmacy, University of London, UK
    FEBS Lett 402:107-10. 1997
    ..It is likely that immunization with liposome-entrapped plasmid DNA involves antigen-presenting cells locally or in the regional draining lymph nodes...
  2. ncbi Genetic vaccines: strategies for optimization
    G Gregoriadis
    Centre for Drug Delivery Research, The School of Pharmacy, London, UK
    Pharm Res 15:661-70. 1998
    ....
  3. ncbi Vaccine entrapment in liposomes
    G Gregoriadis
    The School of Pharmacy, University of London, 29 39 Brunswick Square, London, WC1N 1AX, United Kingdom
    Methods 19:156-62. 1999
    ..On rehydration and sucrose gradient fractionation of the suspension, up to 30% or more of the spores used are associated with generated giant liposomes of similar mean size...
  4. ncbi Polysialic acids: potential in improving the stability and pharmacokinetics of proteins and other therapeutics
    G Gregoriadis
    Centre for Drug Delivery Research School of Pharmacy, University of London, United Kingdom
    Cell Mol Life Sci 57:1964-9. 2000
    ..The highly hydrophilic and innocuous nature of polysialic acids renders them suitable as a means to prolong the circulation of peptides and proteins...
  5. ncbi DNA vaccines: a role for liposomes
    G Gregoriadis
    Centre for Drug Delivery Research, School of Pharmacy, University of London, 29 39 Brunswick Square, London, WCIN 1AX, UK
    Curr Opin Mol Ther 1:39-42. 1999
    ..This review deals with the background and progress made so far with DNA vaccines and evaluates the role of liposomes in their optimization...
  6. ncbi Liposome-mediated DNA vaccination: the effect of vesicle composition
    Y Perrie
    Centre for Drug Delivery Research, The School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, UK
    Vaccine 19:3301-10. 2001
    ..Enhanced green fluorescent protein, expression of the gene in terms of fluorescence intensity in the draining lymph nodes, was much greater than in animals treated with the naked plasmid...
  7. ncbi The effect of polysialylation on the immunogenicity and antigenicity of asparaginase: implication in its pharmacokinetics
    A I Fernandes
    Centre for Drug Delivery Research, School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, UK
    Int J Pharm 217:215-24. 2001
    ..Our data suggest that polysialylation of therapeutic enzymes and other proteins may be useful in maintaining their pharmacokinetics in individuals with antibodies to the therapeutic proteins as a result of chronic treatment...