Research Topics
| Brian FurmanSummaryAffiliation: University of Strathclyde Country: UK Publications
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Detail Information
Publications
Modulation of cyclic nucleotides and cyclic nucleotide phosphodiesterases in pancreatic islet beta-cells and intestinal L-cells as targets for treating diabetes mellitusBrian Furman
University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Sciences, Taylor Street, Glasgow G4 0NR, UK
Curr Opin Investig Drugs 7:898-905. 2006..This review will discuss the possibility of targeting cAMP mechanisms in the treatment of type 2 diabetes mellitus, in which insulin release in response to glucose is impaired...
Cyclic AMP signaling in pancreatic isletsBrian Furman
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4ONR, Scotland, UK
Adv Exp Med Biol 654:281-304. 2010..This chapter discusses the formation, destruction and actions of cAMP in the islets with particular emphasis on the beta-cell...
The development of Byetta (exenatide) from the venom of the Gila monster as an anti-diabetic agentBrian L Furman
Strathclyde Institute of Pharmacy and Biomedical Sciences, Robertson Wing Room 501G, 161 Cathedral Street, Glasgow G4 0RE, UK
Toxicon 59:464-71. 2012..Exendin-4 mimicked GLP-1 through stimulating the GLP-1 receptor. The much greater stability of exendin-4 led to its experimental and clinical evaluation as an anti-diabetic agent and its introduction to the market in 2005...
Targeting beta-cell cyclic 3'5' adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A reviewBrian Furman
Department of Physiology and Pharmacology, University of Strathclyde, Strathclyde Institute for Biomedical Sciences, Taylor Street, Glasgow G4 ONR, UK
J Pharm Pharmacol 56:1477-92. 2004....
