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Species | Frances V Fuller-PaceSummaryAffiliation: University of Dundee Country: UK Publications
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Publications
RNA helicases p68 and p72: multifunctional proteins with important implications for cancer developmentFrances V Fuller-Pace
Centre for Oncology and Molecular Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
Future Oncol 7:239-51. 2011..In this article, we review the many functions that have been attributed to p68 and p72 and discuss their potential roles in cancer development...
DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulationFrances V Fuller-Pace
Cancer Biology Group, Division of Pathology and Neuroscience, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
Nucleic Acids Res 34:4206-15. 2006....
The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulatorsFrances V Fuller-Pace
Division of Pathology and Neuroscience, University of Dundee, Ninewells Medical School, Dundee, UK
Biochem Soc Trans 36:609-12. 2008..We shall also discuss evidence indicating that, in some cases at least, p68 and p72 have distinct, non-redundant, roles...
Modulation of transcriptional activity of the DEAD-box family of RNA helicases, p68 (Ddx5) and DP103 (Ddx20), by SUMO modificationF V Fuller-Pace
Cancer Biology Group, Division of Pathology and Neuroscience, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, U K
Biochem Soc Trans 35:1427-9. 2007....
Analysis of the RNA helicase p68 (Ddx5) as a transcriptional regulatorSamantha M Nicol
Centre for Oncology and Molecular Medicine, University of Dundee Ninewells Hospital and Medical School, Dundee, UK
Methods Mol Biol 587:265-79. 2010....
The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific mannerBrian J Wilson
Department of Molecular and Cellular Pathology, Ninewells Medical School, University of Dundee, DD1 9SY, UK
BMC Mol Biol 5:11. 2004..Furthermore these proteins were shown to interact with co-activators p300/CBP and the RNA polymerase II holoenzyme. Taken together these reports suggest a role for p68 and p72 in transcriptional activation...
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressorGaynor J Bates
Department of Molecular and Cellular Pathology, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
EMBO J 24:543-53. 2005..This study represents the first report of the involvement of an RNA helicase in the p53 response, and highlights a novel mechanism by which p68 may act as a tumour cosuppressor in governing p53 transcriptional activity...
Coupling transcription to RNA processing via the p68 DEAD box RNA helicase androgen receptor co-activator in prostate cancerEmma L Clark
Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4AD, UK
Biochem Soc Trans 36:546-7. 2008....
p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiationEric D Jensen
The Cancer Center and Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Cell Biochem 103:1438-51. 2008..Moreover Runx2 has an active role in regulating p68 levels in osteoblast precursors. Thus, crosstalk between Runx2 and p68 controls osteoblast specification and maturation at multiple levels...
The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiationGiuseppina Caretti
Muscle Gene Expression Group, Laboratory of Muscle Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20829, USA
Dev Cell 11:547-60. 2006..These findings reveal that p68/p72 play a critical role in promoting the assembly of proteins required for the formation of the transcription initiation complex and chromatin remodeling...
Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antiseraDongsheng Chen
Department of Cancer Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
Oncogene 21:4921-31. 2002..Finally, we show that ERalpha is phosphorylated at S118 in vivo using immunoblotting of extracts prepared from a series of ERalpha-positive breast tumours...
