Research Topics
| Elpida FragouliSummaryAffiliation: University of Oxford Country: UK Publications
| Collaborators
|
Detail Information
Publications
Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failureElpida Fragouli
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom
Fertil Steril 94:875-87. 2010..To identify and transfer cytogenetically normal embryos after screening all chromosomes of first and second polar bodies (PBs) or trophectoderm samples with the use of comparative genomic hybridization...
Comprehensive molecular cytogenetic analysis of the human blastocyst stageE Fragouli
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
Hum Reprod 23:2596-608. 2008..Although much is known concerning the aneuploidy rates of oocytes, cleavage stage embryos and fetuses during pregnancy, the chromosomal status of blastocysts has been relatively little investigated...
Chromosome abnormalities in the human oocyteE Fragouli
Institute of Reproductive Sciences, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
Cytogenet Genome Res 133:107-18. 2011..Findings obtained from the cytogenetic and molecular analysis of oocytes will be reviewed in this article...
Aneuploidy in the human blastocystE Fragouli
University of Oxford, Nuffield Department of Obstetrics and Gynaecology, Institute of Reproductive Sciences, Oxford, UK
Cytogenet Genome Res 133:149-59. 2011....
Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expressionE Fragouli
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
Mol Hum Reprod 16:570-82. 2010..Additionally, several genes with altered amounts of transcript produce cell surface or excretory molecules, and could potentially serve as targets for non-invasive oocyte aneuploidy assessment...
Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluationElpida Fragouli
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford OX3 9DU, UK
Hum Reprod 26:480-90. 2011..We assessed blastocyst aneuploidy and mosaicism rates and evaluated the accuracy and efficiency of CGH and microarray-CGH (aCGH) for TE analysis...
The relationship between blastocyst morphology, chromosomal abnormality, and embryo genderSamer Alfarawati
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, United Kingdom
Fertil Steril 95:520-4. 2011..To assess correlation between blastocyst morphology and chromosomal status...
Use of comprehensive chromosomal screening for embryo assessment: microarrays and CGHDagan Wells
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
Mol Hum Reprod 14:703-10. 2008..However, more data concerning accuracy and further reductions in the price of tests will be necessary before microarrays can be widely applied...
Comparative genomic hybridization of oocytes and first polar bodies from young donorsE Fragouli
Reprogenetics UK, Oxford, UK
Reprod Biomed Online 19:228-37. 2009..The data obtained during this study also illustrate that CGH accurately and efficiently detects aneuploidy, confirming that it is suitable for application in a clinical setting for the assessment of oocytes, via PB analysis...
Biomolecules of human female fertility--potential therapeutic targets for pharmaceutical designZhongwei Huang
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK, OX3 9DU
Curr Pharm Des 18:310-24. 2012....
