Research Topics
Species | Thorsten ForsterSummaryAffiliation: University of Edinburgh Country: UK Publications
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Detail Information
Publications
GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insultsGraeme R Grimes
The Scottish Centre for Genomic Technology and Informatics, University of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK
BMC Genomics 6:178. 2005..As an important first step towards this we present a single searchable database resource containing high-throughput macrophage gene expression studies...- SPRINT: a new parallel framework for RJon Hill
EPCC, The University of Edinburgh, James Clerk Maxwell Building, Mayfield Road, Edinburgh EH93JZ, UK
BMC Bioinformatics 9:558. 2008..A method of exploiting HPC systems, using R, but without recourse to mastering parallel programming paradigms is therefore necessary to analyse genomic data to its fullest... - Triple-target microarray experiments: a novel experimental strategyThorsten Forster
Scottish Centre for Genomic Technology and Informatics, University of Edinburgh, The Chancellor s Building, College of Medicine, 49 Little France Crescent, Edinburgh, EH16 4SB, UK
BMC Genomics 5:13. 2004.... - Temporal profiling of the coding and noncoding murine cytomegalovirus transcriptomesPaul Lacaze
Division of Pathway Medicine, University of Edinburgh Medical School, The Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, United Kingdom
J Virol 85:6065-76. 2011..Evidence is also presented to show, for the first time, genome-wide noncoding and bidirectional transcription at late stages of MCMV infection... - Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-?) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral stateKai A Kropp
Division of Pathway Medicine, University of Edinburgh Medical School, Edinburgh, UK
J Virol 85:10286-99. 2011.... - Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesisMathieu Blanc
Division of Pathway Medicine and Centre for Infectious Diseases, University of Edinburgh, Edinburgh, United Kingdom
PLoS Biol 9:e1000598. 2011..These findings bring a new link between sterol metabolism and interferon antiviral response and support the idea of using host metabolic modifiers of innate immunity as a potential antiviral strategy... - Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signallingPaul Lacaze
Division of Pathway Medicine, The University of Edinburgh, The Chancellor s Building, College of Medicine, Edinburgh, UK
BMC Genomics 10:372. 2009..Genome-wide changes in transcript abundance caused by siRNA activity were measured using exon-level microarrays in the presence or absence of IFNgamma... - Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaintHilary O D Critchley
Centre for Reproductive Biology, Queens Medical Research Institute, The University of Edinburgh, Scotland, UK
Am J Obstet Gynecol 195:406.e1-16. 2006.... - Quantitative analysis of low-abundance peptides in HeLa cell cytoplasm by targeted liquid chromatography/mass spectrometry and stable isotope dilution: emphasising the distinction between peptide detection and peptide identificationThierry Le Bihan
Centre for Systems Biology at Edinburgh, School of Biological Sciences, The University of Edinburgh, Edinburgh, UK
Rapid Commun Mass Spectrom 24:1093-104. 2010..An in silico analysis of the human trypsinosome allows the evaluation of how unique are the sets of features that we are using for peptide detection... - Innate immune response gene expression profiles of N9 microglia are pathogen-type specificClive S McKimmie
Virology, Centre for Infectious Diseases College of Medicine and Veterinary Medicine, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK
J Neuroimmunol 175:128-41. 2006..This study demonstrates that a single glial cell phenotype has an innate capability to detect infection, determine its form and generate specific responses... - Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networksAlastair G Lowrie
Tissue Injury and Repair Group, MRC Centre for Regenerative Medicine, Chancellor s Building, The University of Edinburgh Medical School, Royal Infirmary of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK
Int J Oncol 39:709-18. 2011..Quantitative PCR confirmed direct upregulation of VEGFB. These data reveal PIF-CP as the key mediator of dermcidin-induced proliferation and demonstrate induction of key oncogenic pathways... - Quantitative assessment of human whole blood RNA as a potential biomarker for infectious diseaseClaire L Smith
Division of Pathway Medicine, The University of Edinburgh, The Chancellor s Building, 49 Little France Crescent, Edinburgh, Midlothian, UK EH16 4SB
Analyst 132:1200-9. 2007.... - Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatmentRosemary A L Bayne
MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom
J Androl 29:389-403. 2008.... - Expression profiling of the developing testis in wild-type and Dazl knockout miceKlio Maratou
MRC Human Genetics Unit, Edinburgh, United Kingdom
Mol Reprod Dev 67:26-54. 2004..Mol. Reprod. Dev. 67: 26-54, 2004... - High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decayLars Dölken
Max von Pettenkofer Institute, Ludwig Maximilians University Munich, Munich 80337, Germany
RNA 14:1959-72. 2008.... - Estimation of expression levels in spotted microarrays with saturated pixelsChris A Glasbey
Biomathematics and Statistics Scotland
Stat Appl Genet Mol Biol 6:Article34. 2007..The application to biological data demonstrates the potential for enhancing the dynamic range of detection. Fortran90 subroutines implementing these methods are available at http://www.bioss.ac.uk/~chris... - Locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virusMichael J Allen
Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, United Kingdom
J Virol 80:7699-705. 2006..Secondary-phase transcription may then be conducted in the cytoplasm... - Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarraysPeter G E Kennedy
Glasgow University Department of Neurology, Southern General Hospital, Institute of Neurological Sciences, Glasgow G51 4TF, UK
J Gen Virol 86:2673-84. 2005....