Research Topics
Species | W CooksonSummaryAffiliation: University of Oxford Country: UK Publications
| Collaborators
|
Detail Information
Publications
The alliance of genes and environment in asthma and allergyW Cookson
Wellcome Trust Centre for Human Genetics, Headington, Oxford, UK
Nature 402:B5-11. 1999..Early life seems particularly important, when the initiation of allergic disease may result from genetic and environmental modification of the immune interaction between mother and child...
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility lociW O Cookson
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
Nat Genet 27:372-3. 2001..These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity...
Genetics and genomics of asthma and allergic diseasesWilliam Cookson
University of Oxford, The Wellcome Trust Centre for Human Genetics, Oxford, England
Immunol Rev 190:195-206. 2002..Genetic and genomic studies both provide evidence that epithelial surfaces are active in the induction of allergic disease...
A case study of QTL analysis in a mouse model of asthmaYouming Zhang
Wellcome Trust Centre for Human Genetics, University of Oxford, UK
Methods Mol Biol 195:253-79. 2002
A new gene for asthma: would you ADAM and Eve it?William Cookson
Wellcome Trust Centre for Human Genetics, Oxford, OX3 7BN, UK
Trends Genet 19:169-72. 2003..Although its function is at present unknown, these potential actions of ADAM33 provide many possibilities for further research...
The immunogenetics of asthma and eczema: a new focus on the epitheliumWilliam Cookson
Human Genetics, University of Oxford, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK
Nat Rev Immunol 4:978-88. 2004..Understanding events at the epithelial-cell surface might provide new insights for the development of new treatments for inflammatory epithelial disease...
Is eczema really on the increase worldwide?Hywel Williams
Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, United Kingdom
J Allergy Clin Immunol 121:947-54.e15. 2008..It is unclear whether eczema prevalence is truly increasing worldwide...
Genetic variation in the beta subunit of the high affinity IgE receptor and atopy and asthmaJulian Hopkin
Clin Exp Allergy 36:855-7. 2006
Haplotypes and asthmaMiriam Moffatt
Am J Respir Crit Care Med 171:1066-7. 2005
Making sense of asthma genesWilliam Cookson
N Engl J Med 351:1794-6. 2004
Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locusStephan Weidinger
Department of Dermatology and Allergy, Technische Universitat Munchen, Munchen, Germany
PLoS Genet 4:e1000166. 2008..Our data furthermore confirm association of STAT6 variation with serum IgE levels...
