Research Topics

Andrew J Carnell

Affiliation: University of Liverpool

Country: UK

A practical chemo-enzymatic synthesis of homochiral bicyclo[2.2.2]octane-2,5-dione
Yunfei Luo
Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK
J Org Chem 75:2057-60. 2010
Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure-property relationship
Yunfei Luo
Department of Chemistry, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK
Chem Commun (Camb) 48:3279-81. 2012
Design, synthesis, and in vitro testing of alpha-methylacyl-CoA racemase inhibitors
Andrew J Carnell
Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom
J Med Chem 50:2700-7. 2007

A practical chemo-enzymatic synthesis of homochiral bicyclo[2.2.2]octane-2,5-dione
Yunfei Luo
Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK
J Org Chem 75:2057-60. 2010
..2.2]octane-2,5-dione, the precursor of useful chiral diene ligands, was realized via Diels-Alder reaction and resolution of an enol acetate derivative by immobilized lipases...
Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure-property relationship
Yunfei Luo
Department of Chemistry, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK
Chem Commun (Camb) 48:3279-81. 2012
..The interplay between electronic and steric effects was captured in a robust predictive quantitative structure-property relationship (QSPR) model for enantioselectivity...
Design, synthesis, and in vitro testing of alpha-methylacyl-CoA racemase inhibitors
Andrew J Carnell
Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom
J Med Chem 50:2700-7. 2007
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