Mar Carmena

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, King s Buildings, Edinburgh, Scotland, UK
    Curr Opin Cell Biol 21:796-805. 2009
  2. ncbi The chromosomal passenger complex activates Polo kinase at centromeres
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS Biol 10:e1001250. 2012
  3. ncbi Cytokinesis: the final stop for the chromosomal passengers
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, School of Biological Sciences University of Edinburgh, King s Buildings, Mayfield Road, Edinburgh EH9 3JR, UK
    Biochem Soc Trans 36:367-70. 2008
  4. ncbi The cellular geography of aurora kinases
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, Institute for Cell and Molecular Biology, Kings Buildings, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK
    Nat Rev Mol Cell Biol 4:842-54. 2003
  5. ncbi Drosophila Incenp is required for cytokinesis and asymmetric cell division during development of the nervous system
    Chih Jui Chang
    Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Kings Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK
    J Cell Sci 119:1144-53. 2006
  6. ncbi Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis
    Nathalie Colombié
    Wellcome Trust Centre for Cell Biology, The University of Edinburgh, Edinburgh, UK
    Development 135:3239-46. 2008
  7. ncbi The chromosomal passenger complex: one for all and all for one
    Sandrine Ruchaud
    Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, UK
    Cell 131:230-1. 2007
  8. ncbi Chromosomal passengers: conducting cell division
    Sandrine Ruchaud
    Wellcome Trust Centre for Cell Biology, Institute of Cell and Molecular Biology, University of Edinburgh, Swann Building, King s Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK
    Nat Rev Mol Cell Biol 8:798-812. 2007
  9. ncbi RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate
    Chih Jui Chang
    Wellcome Trust Centre for Cell Biology, Institute for Cell and Molecular Biology, Kings Buildings, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK
    J Cell Sci 116:4715-26. 2003
  10. ncbi Survivin is required for stable checkpoint activation in taxol-treated HeLa cells
    Ana Carvalho
    Chromosome Structure Group, Wellcome Trust Centre for Cell Biology, Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK
    J Cell Sci 116:2987-98. 2003

Collaborators

Detail Information

Publications15

  1. ncbi Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Michael Swann Building, King s Buildings, Edinburgh, Scotland, UK
    Curr Opin Cell Biol 21:796-805. 2009
    ..This review will focus on how interacting proteins make this functional diversity possible by targeting the kinases to different subcellular locations and regulating their activity...
  2. ncbi The chromosomal passenger complex activates Polo kinase at centromeres
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS Biol 10:e1001250. 2012
    ..This crosstalk may enable Polo and Aurora B to achieve a balance wherein microtubule mis-attachments are corrected, but proper attachments are stabilized allowing proper chromosome segregation...
  3. ncbi Cytokinesis: the final stop for the chromosomal passengers
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, School of Biological Sciences University of Edinburgh, King s Buildings, Mayfield Road, Edinburgh EH9 3JR, UK
    Biochem Soc Trans 36:367-70. 2008
    ..The first functional analyses showed evidence of a role of the CPC in the regulation of cytokinesis. In this review, I summarize what we have learned since then about the role of the CPC in the late stages of mitosis and cytokinesis...
  4. ncbi The cellular geography of aurora kinases
    Mar Carmena
    Wellcome Trust Centre for Cell Biology, Institute for Cell and Molecular Biology, Kings Buildings, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK
    Nat Rev Mol Cell Biol 4:842-54. 2003
  5. ncbi Drosophila Incenp is required for cytokinesis and asymmetric cell division during development of the nervous system
    Chih Jui Chang
    Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Kings Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK
    J Cell Sci 119:1144-53. 2006
    ..In addition, the segregation of the cell-fate determinant Prospero in asymmetric neuroblast division is abnormal, suggesting a role for the chromosomal passenger complex in the regulation of this process...
  6. ncbi Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis
    Nathalie Colombié
    Wellcome Trust Centre for Cell Biology, The University of Edinburgh, Edinburgh, UK
    Development 135:3239-46. 2008
    ..We propose that the two functions of Incenp are part of the mechanisms that compensate for the lack of centrosomes during meiotic spindle formation...
  7. ncbi The chromosomal passenger complex: one for all and all for one
    Sandrine Ruchaud
    Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, UK
    Cell 131:230-1. 2007
    ..2007) report the crystal structure of the regulatory subunit complex and reveal how interactions between these proteins promote the targeting and function of the chromosomal passenger complex during mitosis...
  8. ncbi Chromosomal passengers: conducting cell division
    Sandrine Ruchaud
    Wellcome Trust Centre for Cell Biology, Institute of Cell and Molecular Biology, University of Edinburgh, Swann Building, King s Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK
    Nat Rev Mol Cell Biol 8:798-812. 2007
    ....
  9. ncbi RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate
    Chih Jui Chang
    Wellcome Trust Centre for Cell Biology, Institute for Cell and Molecular Biology, Kings Buildings, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK
    J Cell Sci 116:4715-26. 2003
    ..This is not kinetochore-based movement, as the centromere of the affected chromosome is located on the plate. This observation raises the possibility that further unexpected functions for Topo II may remain to be discovered...
  10. ncbi Survivin is required for stable checkpoint activation in taxol-treated HeLa cells
    Ana Carvalho
    Chromosome Structure Group, Wellcome Trust Centre for Cell Biology, Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR, Scotland, UK
    J Cell Sci 116:2987-98. 2003
    ..However, Survivin is required for the maintenance of the checkpoint when it is activated by taxol, which is generally thought to cause a loss of spindle tension...
  11. ncbi A perfect funeral with no corpse
    William C Earnshaw
    Wellcome Trust Centre for Cell Biology, Institute for Cell and Molecular Biology, University of Edinburgh, Edinburgh EH9 3JR, UK
    J Cell Biol 160:989-90. 2003
    ..quot; (Mazia, 1961)..
  12. ncbi INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila
    Tamar D Resnick
    Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA
    Dev Cell 11:57-68. 2006
    ..These results implicate the chromosomal passenger complex in directly regulating MEI-S332 localization and, therefore, the control of sister chromatid cohesion in meiosis...
  13. ncbi MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity
    Helder Maiato
    Instituto de Ciencias Biomedicas de Abel Salazar, Instituto de Biologia Molecular e Celular, Universidade do Porto, 4150 180, Portugal
    J Cell Biol 157:749-60. 2002
    ..Together, these results strongly support the conclusion that MAST/Orbit is required for microtubules to form functional attachments to kinetochores and to maintain spindle bipolarity...
  14. ncbi INCENP at the kinase crossroads
    Mar Carmena
    Nat Cell Biol 8:110-1. 2006
  15. ncbi Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis
    María Teresa Parra
    Departamento de Biologia, Edificio de Biológicas, Universidad Autonoma de Madrid, E 28049 Madrid, Spain
    J Cell Sci 116:961-74. 2003
    ..We discuss the complex dynamic relocalization of the chromosomal passenger complex during prophase I. Additionally, we suggest that this complex may regulate sister-chromatid centromere cohesion during both meiotic divisions...