Research Topics
Genomes and GenesSpecies | David W BurtSummaryAffiliation: University of Edinburgh Country: UK Publications
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Detail Information
Publications
Whole genome comparative studies between chicken and turkey and their implications for avian genome evolutionDarren K Griffin
Department of Biosciences, University of Kent, Canterbury, Kent, CT2 7NJ, UK
BMC Genomics 9:168. 2008..No molecular study has yet examined conservation of avian microchromosomes, nor differences in copy number variants (CNVs) between birds...
The Chicken Gene Nomenclature Committee reportDavid W Burt
Department of Genomics and Genetics, Roslin Institute and Royal Dick School of Veterinary Studies, Midlothian, UK
BMC Genomics 10:S5. 2009..The CGNC will develop standardized nomenclature in consultation with the research community and relies on the support of the research community to ensure that the nomenclature facilitates comparative and genomic studies...
The cattle genome reveals its secretsDavid W Burt
Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian EH25 9PS, UK
J Biol 8:36. 2009..The members of the Bovine Genome Consortium have published a series of papers on the assembly and what the sequence reveals so far about the biology of this ruminant and the consequences of its domestication...
Development of a chicken 5 K microarray targeted towards immune functionJacqueline Smith
Division of Genetics and Genomics, Roslin Institute, Roslin, Edinburgh, Midlothian, EH25 9PS, UK
BMC Genomics 7:49. 2006..The creation of an immune-related array is highly valuable in determining the host immune response in relation to infection with a wide variety of bacterial and viral diseases...
Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene productsValerie Garceau
The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, United Kingdom
J Leukoc Biol 87:753-64. 2010..These studies demonstrate that there are two separate ligands for a functional CSF1R across all vertebrates...
Comparative mapping in farm animalsDavid W Burt
UK Centre for Functional Genomics in Farm Animanls, Department of Genomics and Bioinformatics, Roslin Institute Edinburgh, Midlothian, UK
Brief Funct Genomic Proteomic 1:159-68. 2002....
Systems analysis of immune responses in Marek's disease virus-infected chickens identifies a gene involved in susceptibility and highlights a possible novel pathogenicity mechanismJacqueline Smith
The Roslin Institute and R D SVS, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdom
J Virol 85:11146-58. 2011....
Analysis of the rdd locus in chicken: a model for human retinitis pigmentosaDavid W Burt
Division of Genomics and Bioinformatics, Roslin Institute, Edinburgh, Midlothian, UK
Mol Vis 9:164-70. 2003..Linkage mapping places rdd in a region homologous to human chromosomes 9p and 5q. Candidate disease genes or loci include PDE6A, WGN1, and USH2C. This is the first use of genetic mapping in a chicken model of human disease...
The chicken genome and the developmental biologistDavid W Burt
Department of Genomics and Bioinformatics, Roslin Institute Edinburgh, Midlothian EH25 9PS, UK
Mech Dev 121:1129-35. 2004..In this paper we review progress in chicken genomics and discuss how the new tools and information on the chicken genome can help the developmental biologists now and in the future...
Molecular evolution of the vertebrate TLR1 gene family--a complex history of gene duplication, gene conversion, positive selection and co-evolutionYinhua Huang
Division of Genetics and Genomics, The Roslin Institute and R D SVS, University of Edinburgh, Roslin, Midlothian EH25 9PS, UK
BMC Evol Biol 11:149. 2011....
Chicken genome: current status and future opportunitiesDavid W Burt
Department of Genomics and Genetics, Roslin Institute Edinburgh, Midlothian EH25 9PS, United Kingdom
Genome Res 15:1692-8. 2005..Many of the features of the chicken genome and its biology make it an ideal organism for studies in development and evolution, along with applications in agriculture and medicine...
Chicken genomics charts a path to the genome sequenceDavid W Burt
Department of Genomics and Bioinformatics, Roslin Institute Edinburgh, Roslin, Midlothian, EH25 9PS, UK
Brief Funct Genomic Proteomic 3:60-7. 2004..No other animal species have been phenotyped and selected so intensively as agricultural animals and thus there is much to be learned in basic and medical biology from this research...
Evolution of the chicken Toll-like receptor gene family: a story of gene gain and gene lossNicholas D Temperley
Department of Genomics and Genetics, Roslin Institute Edinburgh, Roslin, Midlothian EH25 9PS, UK
BMC Genomics 9:62. 2008..This study takes advantage of the recently sequenced chicken genome to determine the complete chicken TLR repertoire and place it in context of vertebrate genomic evolution...
Identification of a non-mammalian leptin-like gene: characterization and expression in the tiger salamander (Ambystoma tigrinum)Timothy Boswell
Division of Genetics and Genomics, Roslin Institute Edinburgh, Roslin, Midlothian EH25 9PS, UK
Gen Comp Endocrinol 146:157-66. 2006..The characterization of a salamander leptin-like gene provides a basis for understanding how the structure and functions of leptin have altered during the evolution of tetrapod vertebrates...
Mapping quantitative trait loci and identification of genes that control fatness in poultryDavid W Burt
Department of Genomics and Bioinformatics, Roslin Institute Edinburgh, Roslin, Midlothian EH25 9PS, UK
Proc Nutr Soc 61:441-6. 2002..Progress in mapping quantitative trait loci for growth and fatness traits will be discussed, as an application of these new technologies and approaches in the study of avian physiology and genetics...
In-silico identification of chicken immune-related genesJacqueline Smith
Division of Genomics and Bioinformatics, Roslin Institute, EH25 9PS, Roslin Edinburgh, Midlothian, UK
Immunogenetics 56:122-33. 2004..The identification of these kinds of genes will allow further study of avian immunology and will pave the way for large-scale immune-related microarray experiments, giving new insight into functional and evolutionary studies...
A genome-wide linkage study in families with major depression and co-morbid unexplained swellingCarl A Anderson
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK
Am J Med Genet B Neuropsychiatr Genet 147:356-62. 2008....
Comparative mapping of human Chromosome 19 with the chicken shows conserved synteny and gives an insight into chromosomal evolutionJacqueline Smith
Division of Genomics and Bioinformatics, Roslin Institute, Roslin Edinburgh, Midlothian EH25 9PS, UK
Mamm Genome 13:310-5. 2002..The ancestral nature of the chicken karyotype is demonstrated and may prove to be an excellent tool for studying genome evolution...
