Richard J Boys

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi Analysing time course microarray data using Bioconductor: a case study using yeast2 Affymetrix arrays
    Colin S Gillespie
    School of Mathematics and Statistics, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK
    BMC Res Notes 3:81. 2010
  2. ncbi A Bayesian approach to DNA sequence segmentation
    Richard J Boys
    School of Mathematics and Statistics, Newcastle University, Newcastle upon Tyne, UK
    Biometrics 60:573-81; discussion 581-8. 2004
  3. ncbi Bayesian inference for stochastic epidemic models with time-inhomogeneous removal rates
    Richard J Boys
    School of Mathematics and Statistics, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    J Math Biol 55:223-47. 2007
  4. ncbi A mathematical model of ageing in yeast
    Colin S Gillespie
    Henry Wellcome Laboratory for Biogerontology Research, SCMS Gerontology, University of Newcastle, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK
    J Theor Biol 229:189-96. 2004
  5. ncbi Modelling the actions of chaperones and their role in ageing
    Carole J Proctor
    Henry Wellcome Laboratory for Biogerontology Research, School of Clinical and Medical Sciences Gerontology, University of Newcastle, Newcastle upon Tyne NE4 6BE, UK
    Mech Ageing Dev 126:119-31. 2005
  6. ncbi Tools for the SBML Community
    Colin S Gillespie
    School of Mathematics and Statistics, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
    Bioinformatics 22:628-9. 2006
  7. ncbi Towards an e-biology of ageing: integrating theory and data
    Thomas B L Kirkwood
    Institute for Ageing and Heath, University of Newcastle, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK
    Nat Rev Mol Cell Biol 4:243-9. 2003
  8. ncbi A compositional segmentation of the human mitochondrial genome is related to heterogeneities in the guanine mutation rate
    David C Samuels
    Virginia Bioinformatics Institute, Virginia Polytechnic and State University, Blacksburg, VA 24061, USA
    Nucleic Acids Res 31:6043-52. 2003

Detail Information

Publications8

  1. ncbi Analysing time course microarray data using Bioconductor: a case study using yeast2 Affymetrix arrays
    Colin S Gillespie
    School of Mathematics and Statistics, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK
    BMC Res Notes 3:81. 2010
    ..However, proper statistical analysis of time-course data requires the use of more sophisticated tools and complex statistical models...
  2. ncbi A Bayesian approach to DNA sequence segmentation
    Richard J Boys
    School of Mathematics and Statistics, Newcastle University, Newcastle upon Tyne, UK
    Biometrics 60:573-81; discussion 581-8. 2004
    ..The method is applied to the segmentation of the bacteriophage lambda genome, a common benchmark sequence used for the comparison of statistical segmentation algorithms...
  3. ncbi Bayesian inference for stochastic epidemic models with time-inhomogeneous removal rates
    Richard J Boys
    School of Mathematics and Statistics, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    J Math Biol 55:223-47. 2007
    ..The analyses highlight the importance of allowing for time dependence by contrasting the predictive distributions for the removal times and comparing them with the observed data...
  4. ncbi A mathematical model of ageing in yeast
    Colin S Gillespie
    Henry Wellcome Laboratory for Biogerontology Research, SCMS Gerontology, University of Newcastle, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK
    J Theor Biol 229:189-96. 2004
    ....
  5. ncbi Modelling the actions of chaperones and their role in ageing
    Carole J Proctor
    Henry Wellcome Laboratory for Biogerontology Research, School of Clinical and Medical Sciences Gerontology, University of Newcastle, Newcastle upon Tyne NE4 6BE, UK
    Mech Ageing Dev 126:119-31. 2005
    ....
  6. ncbi Tools for the SBML Community
    Colin S Gillespie
    School of Mathematics and Statistics, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
    Bioinformatics 22:628-9. 2006
    ..AVAILABILITY: All tools described are available from http://www.basis.ncl.ac.uk/software and are licensed under GNU General Public License...
  7. ncbi Towards an e-biology of ageing: integrating theory and data
    Thomas B L Kirkwood
    Institute for Ageing and Heath, University of Newcastle, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK
    Nat Rev Mol Cell Biol 4:243-9. 2003
    ..We describe how a new web-based modelling initiative is seeking to integrate data and hypotheses from diverse biological sources...
  8. ncbi A compositional segmentation of the human mitochondrial genome is related to heterogeneities in the guanine mutation rate
    David C Samuels
    Virginia Bioinformatics Institute, Virginia Polytechnic and State University, Blacksburg, VA 24061, USA
    Nucleic Acids Res 31:6043-52. 2003
    ..This has important implications for our understanding of mtDNA evolution and its use as a 'molecular clock' to determine the rate of population and species divergence...