Cherie Blenkiron

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Differential expression of selected histone modifier genes in human solid cancers
    Hilal Ozdag
    Department of Oncology, Hutchison MRC Research Centre, University of Cambridge, Cambridge CB2 2XZ, UK
    BMC Genomics 7:90. 2006
  2. ncbi MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
    Cherie Blenkiron
    Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Genome Biol 8:R214. 2007
  3. ncbi PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes
    Anna Git
    Department of Oncology, Breast Cancer Functional Genomics Laboratory, Cancer Research UK Cambridge Research Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Breast Cancer Res 10:R54. 2008
  4. ncbi Characterisation of microRNA expression in post-natal mouse mammary gland development
    Stefanie Avril-Sassen
    Breast Cancer Functional Genomics Laboratory, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK
    BMC Genomics 10:548. 2009
  5. ncbi High-resolution magic angle spinning 1H NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma
    Julian L Griffin
    Department of Biochemistry, University of Cambridge, UK
    Anal Chem 78:1546-52. 2006
  6. ncbi miRNAs in cancer: approaches, aetiology, diagnostics and therapy
    Cherie Blenkiron
    The Wellcome Trust Cancer Research, UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK
    Hum Mol Genet 16:R106-13. 2007
  7. ncbi Identification of clinically relevant genes on chromosome 11 in a functional model of ovarian cancer tumor suppression
    Euan A Stronach
    Cancer Research UK, Edinburgh Oncology Unit, University of Edinburgh Cancer Research Centre, Edinburgh, Scotland, United Kingdom
    Cancer Res 63:8648-55. 2003

Collaborators

Detail Information

Publications7

  1. ncbi Differential expression of selected histone modifier genes in human solid cancers
    Hilal Ozdag
    Department of Oncology, Hutchison MRC Research Centre, University of Cambridge, Cambridge CB2 2XZ, UK
    BMC Genomics 7:90. 2006
    ..Expression of each gene in 225 samples (135 primary tumours, 47 cancer cell lines, and 43 normal tissues) was analysedby QRT-PCR, normalized with 8 housekeeping genes, and given as a ratio by comparison with a universal reference RNA...
  2. ncbi MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
    Cherie Blenkiron
    Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Genome Biol 8:R214. 2007
    ..MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants and animals, often act post-transcriptionally to inhibit gene expression...
  3. ncbi PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes
    Anna Git
    Department of Oncology, Breast Cancer Functional Genomics Laboratory, Cancer Research UK Cambridge Research Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Breast Cancer Res 10:R54. 2008
    ..Therefore, identification of cell lines with normal-like expression profiles is of paramount importance in studies of normal gene regulation...
  4. ncbi Characterisation of microRNA expression in post-natal mouse mammary gland development
    Stefanie Avril-Sassen
    Breast Cancer Functional Genomics Laboratory, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK
    BMC Genomics 10:548. 2009
    ..In parallel whole-genome mRNA expression data were obtained...
  5. ncbi High-resolution magic angle spinning 1H NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma
    Julian L Griffin
    Department of Biochemistry, University of Cambridge, UK
    Anal Chem 78:1546-52. 2006
    ..This study demonstrates how combined transcriptomic and metabolomic studies of tumors can be used to understand the molecular events that accompany well documented metabolic perturbations during cell death processes...
  6. ncbi miRNAs in cancer: approaches, aetiology, diagnostics and therapy
    Cherie Blenkiron
    The Wellcome Trust Cancer Research, UK Gurdon Institute and Department of Biochemistry, University of Cambridge, Cambridge, UK
    Hum Mol Genet 16:R106-13. 2007
    ..Some miRNAs and their target sites were found to be mutated in cancer. MiRNAs may have great diagnostic potential for human cancer and even miRNA-based cancer therapies may be on the horizon...
  7. ncbi Identification of clinically relevant genes on chromosome 11 in a functional model of ovarian cancer tumor suppression
    Euan A Stronach
    Cancer Research UK, Edinburgh Oncology Unit, University of Edinburgh Cancer Research Centre, Edinburgh, Scotland, United Kingdom
    Cancer Res 63:8648-55. 2003
    ..The detailed contextual characterization of these genes will determine the extent of their involvement in neoplastic development...