Detail Information
Publications
B cells acquire antigen from target cells after synapse formationF D Batista
Medical Research Laboratory of Molecular Biology, Cambridge, UK
Nature 411:489-94. 2001..Synapse formation and antigen acquisition will probably enhance the activation of B cells at low antigen concentration, allow context-dependent antigen recognition and enhance the linking of B- and T-cell epitopes...
Memory in the B-cell compartment: antibody affinity maturationM S Neuberger
Medical Research Council Laboratory of Molecular Biology, Cambridge, UK
Philos Trans R Soc Lond B Biol Sci 355:357-60. 2000..We also compare and draw parallels between the two processes, which underpin the generation of secondary-response antibodies: V gene somatic hypermutation and immunoglobulin heavy-chain class switching...
