Research Topics
Genomes and GenesSpecies | J B BardSummaryAffiliation: University of Edinburgh Country: UK Publications
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Detail Information
Publications
Ontologies in biology: design, applications and future challengesJonathan B L Bard
Bioinformatics, Biomedical Sciences University of Edinburgh, Edinburgh EH8 9XD, UK
Nat Rev Genet 5:213-22. 2004
Ontologies: Formalising biological knowledge for bioinformaticsJonathan Bard
Dept of Biomedical Sciences, Edinburgh University, EH8 9XD, UK
Bioessays 25:501-6. 2003..This article considers the production, formulation and types of bio-ontologies together with the reasons why they are so useful...
A systems biology representation of developmental anatomyJonathan Bard
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
J Anat 218:591-9. 2011....
Anatomics: the intersection of anatomy and bioinformaticsJonathan B L Bard
Division of Biomedical Science, University of Edinburgh, UK
J Anat 206:1-16. 2005..It is suggested that the appropriate term for the analysis, computer formulation and use of the anatome is anatomics...
An ontology for cell typesJonathan Bard
Department of Biomedical Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK
Genome Biol 6:R21. 2005..The ontology is freely available at http://obo.sourceforge.net/ and can be viewed using standard ontology visualization tools such as OBO-Edit and COBrA...
Systems developmental biology: the use of ontologies in annotating models and in identifying gene function within and across speciesJonathan Bard
School of Biomedical Sciences, Edinburgh University, Edinburgh, EH8 9XD, UK
Mamm Genome 18:402-11. 2007..Second, Boolean analysis of the G-E profiles of the mesenchyme-to-epithelium transitions that take place during mouse development suggest Lhx1, Foxc1, and Meox1 as candidate transcription factors for mediating this process...
A bioinformatics approach for identifying candidate transcriptional regulators of mesenchyme-to-epithelium transitions in mouse embryosJonathan B L Bard
Computational Biology, Research Group, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
Dev Dyn 237:2748-54. 2008..GXD-search is downloadable from http://www.aiai.ed.ac.uk/project/biosphere/GXD-search.html...
Growth and death in the developing mammalian kidney: signals, receptors and conversationsJonathan B L Bard
Department of Biomedical Science, Edinburgh University, Edinburgh EH8 9XD, Scotland, UK
Bioessays 24:72-82. 2002..It also points to some unanswered questions, the most intriguing being what role does apoptosis play during normal kidney development?..
Early nephron formation in the developing mouse kidneyJ B Bard
Department of Biomedical Sciences, University of Edinburgh, UK
J Anat 199:385-92. 2001..These observations revise our knowledge of the timing and process of nephron initiation...
Ontologies of developmental anatomy: their current and future rolesJ Bard
Department of Biomedical Sciences, University of Edinburgh, UK
Brief Bioinform 2:289-99. 2001....
A bioinformatics approach to investigating developmental pathways in the kidney and other tissuesJ B Bard
Department of Biomedical Science, Edinburgh University, United Kingdom
Int J Dev Biol 43:397-403. 1999..This paper also considers both the types of tools that will be necessary and the databases on which they will operate...
Expression and genomic characterization of protein phosphatase inhibitor-1: a novel marker for mesothelium in the mouseL McLaren
Department of Biomedical Sciences and Centre for Developmental Biology, Hugh Robson Building, University of Edinburgh, EH8 9XD, Edinburgh, UK
Mech Dev 96:237-41. 2000..The blast cells of the kidney do not express I-1. We conclude that I-1 is a marker for mesothelium...
A three-dimensional model of the mouse at embryonic day 9R M Brune
Anatomy Section, University of Edinburgh, United Kingdom
Dev Biol 216:457-68. 1999..This reconstruction and its associated anatomy are available in a variety of data formats with some supporting software from http:@genex.hgu.mrc.ac.uk/...
OBO Explorer: an editor for Open Biomedical Ontologies in OWLStuart Aitken
School of Informatics, University of Edinburgh, 11 Crichton Street, Edinburgh, UK
Bioinformatics 24:443-4. 2008..We present an ontology editor that allows end users to work directly with this OWL representation of OBO format ontologies. AVAILABILITY: http://www.aiai.ed.ac.uk/project/cobra-ct...
COBrA: a bio-ontology editorStuart Aitken
School of Informatics, The University of Edinburgh, Edinburgh EH8 9LE, UK
Bioinformatics 21:825-6. 2005..In addition to the Gene Ontology and Open Biology Ontologies formats, COBrA can import and export ontologies in the Semantic Web formats RDF, RDFS and OWL...
The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryoJ F Armstrong
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
Mech Dev 40:85-97. 1993..The data indicate that WT1 plays a role in mediating some cases of the mesenchyme-to-epithelial transition, but its expression elsewhere argues that it has other tissue-specific roles in development...
The mouse 14-3-3 epsilon isoform, a kinase regulator whose expression pattern is modulated in mesenchyme and neuronal differentiationJ E McConnell
MRC Human Genetics Unit, Edinburgh, United Kingdom
Dev Biol 169:218-28. 1995..The results as a whole thus argue for the 14-3-3 epsilon isoform playing roles in neural development and in early mesenchyme, with this latter function being lost or replaced as the tissue differentiates...
EMAP and EMAGE: a framework for understanding spatially organized dataRichard A Baldock
MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, UK
Neuroinformatics 1:309-25. 2003....
Pathbase: a new reference resource and database for laboratory mouse pathologyPaul N Schofield
Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
Radiat Prot Dosimetry 112:525-8. 2004..The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology...
Pathbase: a database of mutant mouse pathologyPaul N Schofield
Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
Nucleic Acids Res 32:D512-5. 2004..The database interface is designed to have optimal browser and platform compatibility and to interact directly with other web-based mouse genetic resources...
Apoptosis in the cortex of the developing mouse kidneyJonathan G D Foley
Department of Biomedical Sciences, Edinburgh University, Edinburgh EH8 9XD, UK
J Anat 201:477-84. 2002....
Using bioinformatics to identify kidney genesJonathan B L Bard
Department of Biomedical Sciences, Edinburgh University, Edinburgh EH8 9XD, UK
Nephrol Dial Transplant 17:62-4. 2002..Future databases will also include graphical data, and this knowledge will provide a further level of insight. These databases and tools are discussed here...
The growth and morphogenesis of the early mouse mandible: a quantitative analysisThaya Ramaesh
Department of Biomedical Sciences, Edinburgh University, Edinburgh EH8 9XD, UK
J Anat 203:213-22. 2003....
An ontology of human developmental anatomyAmy Hunter
Bioinformatics Group, Division of Biomedical Sciences, Hugh Robson Building, University of Edinburgh, UK
J Anat 203:347-55. 2003..The third gives the second version in GO ontology syntax (with standard IDs for each tissue) and can be downloaded from both the genex and the Open Biological Ontology sites (http://obo.sourceforge.net/)...
