Boris Adryan

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi BioSAVE: display of scored annotation within a sequence context
    Richard F Pollock
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    BMC Bioinformatics 9:157. 2008
  2. ncbi Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila
    Boris Adryan
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    Genome Biol 8:R167. 2007
  3. ncbi FlyTF: a systematic review of site-specific transcription factors in the fruit fly Drosophila melanogaster
    Boris Adryan
    MRC Laboratory of Molecular Biology Cambridge CB2 2QH, UK
    Bioinformatics 22:1532-3. 2006
  4. ncbi Stability and dynamics of polycomb target sites in Drosophila development
    Camilla Kwong
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 4:e1000178. 2008
  5. ncbi CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex
    Eimear E Holohan
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 3:e112. 2007
  6. ncbi FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
    Ulrike Pfreundt
    Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Nucleic Acids Res 38:D443-7. 2010
  7. ncbi Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors
    Fred Bernard
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK
    Development 137:2633-42. 2010
  8. ncbi Scoring overlapping and adjacent signals from genome-wide ChIP and DamID assays
    Audrey Qiuyan Fu
    Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge, UK
    Mol Biosyst 5:1429-38. 2009
  9. ncbi Biases in Drosophila melanogaster protein trap screens
    Jelena Aleksic
    Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK
    BMC Genomics 10:249. 2009
  10. ncbi The developmental expression dynamics of Drosophila melanogaster transcription factors
    Boris Adryan
    Computational Biology Group, Structural Studies Division, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Genome Biol 11:R40. 2010

Detail Information

Publications15

  1. ncbi BioSAVE: display of scored annotation within a sequence context
    Richard F Pollock
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    BMC Bioinformatics 9:157. 2008
    ..Unfortunately, many visualisation solutions are somewhat static in the way they handle such score cutoffs...
  2. ncbi Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila
    Boris Adryan
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    Genome Biol 8:R167. 2007
    ..Immunolocalization studies suggest that there are several hundred Su(Hw) sites in the genome, but few of these endogenous Su(Hw) binding sites have been identified...
  3. ncbi FlyTF: a systematic review of site-specific transcription factors in the fruit fly Drosophila melanogaster
    Boris Adryan
    MRC Laboratory of Molecular Biology Cambridge CB2 2QH, UK
    Bioinformatics 22:1532-3. 2006
    ..We propose a set of 753 TFs in the fruit fly, of which 23 are confident novel predictions of this function for previously uncharacterized proteins...
  4. ncbi Stability and dynamics of polycomb target sites in Drosophila development
    Camilla Kwong
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 4:e1000178. 2008
    ..Pc/Pho binding does not preclude transcription, but levels of Pc/Pho binding change during development, and loss of Pc/Pho binding can be associated with both stable gene activity and inactivity...
  5. ncbi CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex
    Eimear E Holohan
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 3:e112. 2007
    ..Comparison of the locations of the CTCF sites with characterised Polycomb target sites and histone modification provides support for the domain model of BX-C regulation...
  6. ncbi FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
    Ulrike Pfreundt
    Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Nucleic Acids Res 38:D443-7. 2010
    ....
  7. ncbi Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors
    Fred Bernard
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK
    Development 137:2633-42. 2010
    ....
  8. ncbi Scoring overlapping and adjacent signals from genome-wide ChIP and DamID assays
    Audrey Qiuyan Fu
    Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge, UK
    Mol Biosyst 5:1429-38. 2009
    ..We provide a simple guide to some of the statistical tools used by these methods...
  9. ncbi Biases in Drosophila melanogaster protein trap screens
    Jelena Aleksic
    Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK
    BMC Genomics 10:249. 2009
    ..Despite recent efforts aimed at achieving comprehensive coverage of the genes encoded in the Drosophila genome, the repertoire of genes that yield protein traps is still small...
  10. ncbi The developmental expression dynamics of Drosophila melanogaster transcription factors
    Boris Adryan
    Computational Biology Group, Structural Studies Division, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Genome Biol 11:R40. 2010
    ..Their binding to cis-regulatory modules of target genes mediates the precise cell- and context-specific activation and repression of genes. The expression of TFs should therefore reflect the core expression program of each cell...
  11. ncbi New androgen receptor genomic targets show an interaction with the ETS1 transcription factor
    Charles E Massie
    Uro Oncology Research Group, Department of Oncology, University of Cambridge, Cancer Research UK Cambridge, Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    EMBO Rep 8:871-8. 2007
    ..Binding sequences for the avian erythroblastosis virus E26 homologue (ETS) transcription factor family were also highly enriched, and we uncovered an interaction between the AR and ETS1 at a subset of AR promoter targets...
  12. ncbi Evolution of genes and genomes on the Drosophila phylogeny
    Andrew G Clark
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Nature 450:203-18. 2007
    ..These may prove to underlie differences in the ecology and behaviour of these diverse species...
  13. ncbi Identification of FGF-dependent genes in the Drosophila tracheal system
    Markus Stahl
    Department of Molecular Developmental Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen 37077, Germany
    Gene Expr Patterns 7:202-9. 2007
    ..Thus, we identified and confirmed by quantitative PCR 13 Bnl-dependent genes that are expressed in cells within and outside of the tracheal system...
  14. ncbi Gene-Ontology-based clustering of gene expression data
    Boris Adryan
    Department of Molecular Developmental Biology, Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    Bioinformatics 20:2851-2. 2004
    ..AVAILABILITY: The 32-bit Windows application is freely available at http://www.mpibpc.mpg.de/go-cluster/..
  15. ncbi Drosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development
    Vincent Dammai
    Department of Pathology and Laboratory Medicine, and Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Genes Dev 17:2812-24. 2003
    ..Thus, we propose that awd regulates tracheal cell motility by modulating the FGFR levels, through a dynamin-mediated pathway...