Research Topics
| T J BullSummaryAffiliation: St George's Hospital Medical School Country: UK Publications
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Detail Information
Publications
Further studies on the GS element. A novel mycobacterial insertion sequence (IS1612), inserted into an acetylase gene (mpa) in Mycobacterium avium subsp. silvaticum but not in Mycobacterium avium subsp. paratuberculosisT J Bull
Department of Surgery, St George s Hospital Medical School, Cranmer Terrace, London, UK
Vet Microbiol 77:453-63. 2000..Homologues of the GS element in MTB show a marked similarity of organisation, suggesting a parallel role for these genes in both pathogens...
Mycobacterial interspersed repetitive units (MIRU) differentiate Mycobacterium avium subspecies paratuberculosis from other species of the Mycobacterium avium complexT J Bull
Department of Surgery, St George s Hospital Medical School, Cranmer Terrace, SW17 0RE, London, UK
Mol Cell Probes 17:157-64. 2003..avium complex (MAC) tested. PCR at both loci 1 and 4 also distinguished MAP from Mycobacterium intracellulare. MIRU typing may provide an additional simple and rapid procedure for the differentiation between MAP and other MAC...
Causation of Crohn's disease by Mycobacterium avium subspecies paratuberculosisJ Hermon-Taylor
St George s Hospital Medical School, London, United Kingdom
Can J Gastroenterol 14:521-39. 2000..New drugs as well as effective MAP vaccines for animals and humans are needed. The problems caused by MAP constitute a public health issue of tragic proportions for which a range of remedial measures are urgently needed...
Characterization of IS900 loci in Mycobacterium avium subsp. paratuberculosis and development of multiplex PCR typingT J Bull
Department of Surgery, St George s Hospital Medical School, Cranmer Terrace, London, UK
Microbiology 146:2185-97. 2000..The remaining MPIL type corresponded with seven PstI/BstEII RFLP types. Further resolution of these may come from sequencing the remaining four uncharacterized IS900 loci...
Duplication of genes encoding the immunodominant 38 kDa antigen in Mycobacterium intracellulareH S Thangaraj
M R C Tuberculosis and Related Infections, Unit, Hammersmith Hospital, London, UK
FEMS Microbiol Lett 144:235-40. 1996..We also identified and characterised other pst genes that may constitute an operon. Considering that multiple isoforms of PstS are present in mycobacteria the possible role of pstS1 genes for pathogenesis is discussed...
Study of Mycobacterium avium complex strains isolated from cattle in the Czech Republic between 1996 and 2000L Dvorska
Veterinary Research Institute, Hudcova 70, 62132 Brno, Czech Republic
Vet Microbiol 99:239-50. 2004..These revealed 11 distinct IS901 RFLP types and three IS1245 RFLP profiles. Polyclonal infection of individual animals was detected by IS901/IS1245 typing in 2 of the 17 selected isolates...
Mycobacterium avium subsp. paratuberculosis in the catchment area and water of the River Taff in South Wales, United Kingdom, and its potential relationship to clustering of Crohn's disease cases in the city of CardiffR W Pickup
Centre for Ecology and Hydrology, Library Ave, Bailrigg, Lancaster LA21 4AP, United Kingdom
Appl Environ Microbiol 71:2130-9. 2005..A topographical relief map shows that this gap is directly opposite a valley open to the prevailing southwesterly winds. This would influence the distribution of aerosols carrying M. avium subsp. paratuberculosis from the river...
Mycobacterium avium subsp. paratuberculosis in lake catchments, in river water abstracted for domestic use, and in effluent from domestic sewage treatment works: diverse opportunities for environmental cycling and human exposureR W Pickup
Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA21 4AP, United Kingdom
Appl Environ Microbiol 72:4067-77. 2006..avium subsp. paratuberculosis. Since Lake Ambleside discharges into Lake Windermere, which is available for domestic supply, there is a potential for these organisms to cycle within human populations...
