Research Topics
| Najib M RahmanSummaryCountry: UK Publications
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Detail Information
Publications
Pleural effusion: a structured approach to careNajib M Rahman
Oxford Pleural Diseases Unit, Oxford Centre for Respiratory Medicine, Churchill Hospital Oxford OX3 7LJ, UK
Br Med Bull 72:31-47. 2004..This review provides a structured approach to the investigation of the patient with a pleural effusion. This should allow an accurate diagnosis to be made with the minimum number of invasive and time-consuming investigations...
Diagnostic accuracy, safety and utilisation of respiratory physician-delivered thoracic ultrasoundNajib M Rahman
Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford OX3 7LJ, UK
Thorax 65:449-53. 2010..Continued liaison with the radiology service has here been demonstrated as a requirement for a physician-based service...
Setting up a respiratory trials unitNajib M Rahman
UKCRC Oxford Respiratory Trials Unit, Oxford Centrefor Respiratory Medicine, Churchill Hospital Site, OxfordRadcliffe Hospital, Headington, Oxford, UK
Respirology 16:64-8. 2011..This article will describe some of the challenges associated with clinical studies and the methods and personnel involved in a clinical trials unit...
The approach to the patient with a parapneumonic effusionNajib M Rahman
Oxford Pleural Diseases Unit, Oxford Centre for Respiratory Medicine, Churchill Hospital Site, Oxford Radcliffe Hospital, Headington, Oxford OX3 7LJ, UK
Clin Chest Med 27:253-66. 2006..Recent data suggest that fibrinolytics do not influence outcomes in pleural infection. The optimal type and timing of surgery remain controversial...
Blood culture bottle culture of pleural fluid in pleural infectionSarah M Menzies
UKCRC Oxford Respiratory Trials Unit, Churchill Hospital, Oxford, UK
Thorax 66:658-62. 2011..Standard pleural fluid culture is negative in ?40% of cases. Culturing pleural fluid in blood culture bottles may increase microbial yield, and is cheap and easy to perform...
Pleural procedures and pleuroscopyJohn M Wrightson
Oxford Pleural Unit, Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford, UK
Respirology 14:796-807. 2009..This review presents a systematic evaluation of the potential complications of common pleural procedures...
Use of indwelling pleural catheters for chronic pleural infectionHelen E Davies
Oxford Pleural Unit, Oxford Centre for Respiratory Medicine, University of Oxford and Oxford Radcliffe NHS Trust, Oxford, OX3 7LJ, UK
Chest 133:546-9. 2008..Long-term indwelling pleural catheters may have a role in maintaining the drainage of a chronically infected pleural space that is not readily treated in other ways...
Pleural interventions: management of acute and chronic pneumothoraxNajib M Rahman
Oxford Pleural Unit and Oxford University, Churchill Hospital, Oxford, United Kingdom
Semin Respir Crit Care Med 29:427-40. 2008..Radiological intervention techniques are valuable in the treatment of complicated pneumothoraces and in certain clinical situations...
Outcome of patients with nonspecific pleuritis/fibrosis on thoracoscopic pleural biopsiesHelen E Davies
Oxford Pleural Unit, Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford Radcliffe NHS Trust, Oxford, UK
Eur J Cardiothorac Surg 38:472-7. 2010....
The relationship between chest tube size and clinical outcome in pleural infectionNajib M Rahman
Oxford Centre for Respiratory Medicine, Oxford Radcliffe Hospital, Oxford, England
Chest 137:536-43. 2010..The optimal choice of chest tube size for the treatment of pleural infection is unknown, with only small cohort studies reported describing the efficacy and adverse events of different tube sizes...
Clinical impact and reliability of pleural fluid mesothelin in undiagnosed pleural effusionsHelen E Davies
Oxford Centre for Respiratory Medicine, University of Oxford, Oxford, UK
Am J Respir Crit Care Med 180:437-44. 2009....
Use of lipoteichoic acid-T for pleurodesis in malignant pleural effusion: a phase I toxicity and dose-escalation studyNajib M Rahman
Oxford Pleural Unit, Oxford Centre for Respiratory Medicine, University of Oxford and Oxford Radcliffe Hospital, Oxford, UK
Lancet Oncol 9:946-52. 2008..We postulated that therapeutically administered LTA-T might produce a similar effect, achieving control of malignant pleural effusion (pleurodesis)...
Image-guided pleural biopsyNajib M Rahman
Oxford Centre for Respiratory Medicine and University of Oxford, Oxford Radcliffe Hospital, UK
Curr Opin Pulm Med 14:331-6. 2008..Obtaining pleural tissue (by blind, image-guided or thoracoscopic pleural biopsy) is therefore a key procedure. Recent evidence provides important information on the relative value of each of these techniques...
Intrapleural use of tissue plasminogen activator and DNase in pleural infectionNajib M Rahman
UKCRC Oxford Respiratory Trials Unit, Oxford Centre for Respiratory Medicine, Nuffield Department of Medicine, University of Oxford, Churchill Hospital Site, Headington, Oxford OX3 7LJ, United Kingdom
N Engl J Med 365:518-26. 2011..Drainage of infected fluid is key to successful treatment, but intrapleural fibrinolytic therapy did not improve outcomes in an earlier, large, randomized trial...
Factors influencing the measurement of pleural fluid pHEleanor K Mishra
Oxford Centre for Respiratory Medicine and University of Oxford, Oxford OX3 7LJ, UK
Curr Opin Pulm Med 15:353-7. 2009..Common variations in the method used to sample pleural fluid affect the accuracy of the value obtained. This article reviews the effects of these variations...
Catheter-tract metastases associated with chronic indwelling pleural cathetersSam M Janes
Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford OX3 7LJ, UK
Chest 131:1232-4. 2007..7% of 45 patients treated with indwelling pleural catheters for malignant pleural effusions. Both clinicians and patients should be aware of this potential complication...
Clinically important factors influencing the diagnostic measurement of pleural fluid pH and glucoseNajib M Rahman
Oxford Centre for Respiratory Medicine and University of Oxford, Oxford, United Kingdom
Am J Respir Crit Care Med 178:483-90. 2008..Accurate pleural fluid pH and glucose measurement is a key component in the diagnosis and management of patients with pleural effusion. Standardized methods of pleural fluid collection have not been defined...
