Research Topics
| Frederick C CampbellSummaryAffiliation: Queen's University Belfast Country: UK Publications
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Detail Information
Publications
Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signalsHaibo Xu
Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, UK
Mol Carcinog 48:758-72. 2009..These findings may be relevant to the cell- or tissue-specificity of vitamin D growth regulation...
Chemopreventive properties of curcuminFrederick C Campbell
Queen s University of Belfast, Department of Surgery, Centre for Cancer and Cell Biology, Belfast, BT12 6BJ, Ireland
Future Oncol 1:405-14. 2005..This review will summarize the unique properties of curcumin that may be exploited for successful clinical cancer prevention...
Rationale for cancer prevention strategies in high-risk ulcerative colitisF C Campbell
Centre for Cancer Research and Cell Biology, Lisburn Road, Queen s University of Belfast
Surgeon 7:96-100. 2009..Against this background, indications for surveillance and prophylactic colectomy in specific clinical situations will be discussed...
The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth controlF C Campbell
Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Lisburn Rd, Belfast BT9 7BL, Northern Ireland, UK
Biochem Pharmacol 79:1-9. 2010..We highlight some differences of VDR growth control relevant to colonic, esophageal, prostate, pancreatic and other cancers and assess the potential for development of selective prevention or treatment strategies...
Apc(MIN) modulation of vitamin D secosteroid growth controlHaibo Xu
Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Northern Ireland, UK
Carcinogenesis 31:1434-41. 2010..APC heterozygosity may promote favourable tissue- or tumour-specific conditions for growth control by vitamin D secosteroid treatment...
The Drosophila ortholog of the endolysosomal membrane protein, endolyn, regulates cell proliferationGuang Qian Zhou
Centre for Cancer Research and Cell Biology, Queen s University of Belfast, Belfast, UK
J Cell Biochem 99:1380-96. 2006..Taken together, these results demonstrate that endolyn is an evolutionarily conserved sialomucin fundamentally involved in cell proliferation in both the human and Drosophila melanogaster...
Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cellsGavin P Collett
Department of Surgery, Centre for Cancer Research and Cell Biology, Queen s University Belfast, Belfast BT12 6BJ, UK
Carcinogenesis 27:1285-91. 2006..Furthermore, curcumin/p65 synergy in promotion of apoptosis cannot be attributed to active repression of NFkappaB anti-apoptotic genes...
