M N Moore

Summary

Affiliation: Plymouth Marine Laboratory
Country: UK

Publications

  1. ncbi Biocomplexity: the post-genome challenge in ecotoxicology
    Michael N Moore
    United Nations Industrial Development Organization (UNIDO, Vienna International Centre, PO Box 300, Vienna, Austria
    Aquat Toxicol 59:1-15. 2002
  2. ncbi Do nanoparticles present ecotoxicological risks for the health of the aquatic environment?
    M N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Environ Int 32:967-76. 2006
  3. ncbi A synopsis of the Joint Environment and Human Health Programme in the UK
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, UK
    Environ Health 8:S1. 2009
  4. ncbi Autophagy: role in surviving environmental stress
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Mar Environ Res 62:S420-5. 2006
  5. ncbi Lysosomal and autophagic reactions as predictive indicators of environmental impact in aquatic animals
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, UK
    Autophagy 2:217-20. 2006
  6. ncbi Environmental prognostics: an integrated model supporting lysosomal stress responses as predictive biomarkers of animal health status
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, United Kingdom
    Mar Environ Res 61:278-304. 2006
  7. ncbi Autophagic and lysosomal reactions to stress in the hepatopancreas of blue mussels
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Aquat Toxicol 84:80-91. 2007
  8. ncbi An integrated biomarker-based strategy for ecotoxicological evaluation of risk in environmental management
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, West Hoe, Plymouth PL1 3DH, UK
    Mutat Res 552:247-68. 2004
  9. ncbi Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, UK
    Autophagy 4:254-6. 2008
  10. ncbi Diet restriction induced autophagy: a lysosomal protective system against oxidative- and pollutant-stress and cell injury
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Mar Environ Res 58:603-7. 2004

Detail Information

Publications18

  1. ncbi Biocomplexity: the post-genome challenge in ecotoxicology
    Michael N Moore
    United Nations Industrial Development Organization (UNIDO, Vienna International Centre, PO Box 300, Vienna, Austria
    Aquat Toxicol 59:1-15. 2002
    ....
  2. ncbi Do nanoparticles present ecotoxicological risks for the health of the aquatic environment?
    M N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Environ Int 32:967-76. 2006
    ..Although current toxicity testing protocols should be generally applicable to identify harmful effects associated with nanoparticles, research into new methods is required to address the special properties of nanomaterials...
  3. ncbi A synopsis of the Joint Environment and Human Health Programme in the UK
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, UK
    Environ Health 8:S1. 2009
    ..This has not only helped build new research groupings, but has also led to exciting new scientific developments as described in this issue of Environmental Health...
  4. ncbi Autophagy: role in surviving environmental stress
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Mar Environ Res 62:S420-5. 2006
    ....
  5. ncbi Lysosomal and autophagic reactions as predictive indicators of environmental impact in aquatic animals
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, UK
    Autophagy 2:217-20. 2006
    ..Finally, coupled measurement of lysosomal-autophagic reactions and modelling is proposed as a practical toolbox for predicting toxic environmental risk...
  6. ncbi Environmental prognostics: an integrated model supporting lysosomal stress responses as predictive biomarkers of animal health status
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, United Kingdom
    Mar Environ Res 61:278-304. 2006
    ..More speculatively, the use of coupled empirical measurements of biomarker reactions and modelling is proposed as a practical approach to the development of an operational toolbox for predicting the health of the environment...
  7. ncbi Autophagic and lysosomal reactions to stress in the hepatopancreas of blue mussels
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Aquat Toxicol 84:80-91. 2007
    ..Finally, we discuss the possibility of low level triggering of autophagy in mussels by fluctuating environmental regimes providing a mechanism for tolerance to environmental stress...
  8. ncbi An integrated biomarker-based strategy for ecotoxicological evaluation of risk in environmental management
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, West Hoe, Plymouth PL1 3DH, UK
    Mutat Res 552:247-68. 2004
    ....
  9. ncbi Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, UK
    Autophagy 4:254-6. 2008
    ....
  10. ncbi Diet restriction induced autophagy: a lysosomal protective system against oxidative- and pollutant-stress and cell injury
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Mar Environ Res 58:603-7. 2004
    ..g., protein carbonyls, protein adducts, etc.) and that this contributes to stress resistance...
  11. ncbi Is toxicological pathology characterised by a loss of system complexity?
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, UK
    Mar Environ Res 69:S37-41. 2010
    ..In summary for the model described here, network and graph theory appear to provide a mathematical formalism that can facilitate the system-level interpretation of health and dysfunction in living cells...
  12. ncbi Pathological reactions and recovery of hepatopancreatic digestive cells from the marine snail Littorina littorea following exposure to a polycyclic aromatic hydrocarbon
    D M Lowe
    Plymouth Marine Laboratory, Prospect Place, West Hoe, Plymouth PL1 3DH, United Kingdom
    Mar Environ Res 61:457-70. 2006
    ..Finally, the results indicate that stress induced by chronic exposure to a PAH is reversible...
  13. ncbi Integration of biochemical, histochemical and toxicogenomic indices for the assessment of health status of mussels from the Tamar Estuary, U.K
    J P Shaw
    Plymouth Marine Laboratory, Prospect Place, Plymouth PL13DH, UK
    Mar Environ Res 72:13-24. 2011
    ..It is concluded that the MES is a valuable tool that permits integration and interpretation of complex sets of biomarker data by identifying the biological meaning of biomarker changes...
  14. ncbi Environmental prognostics: is the current use of biomarkers appropriate for environmental risk evaluation?
    J Icarus Allen
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Mar Environ Res 58:227-32. 2004
    ..These are urgently needed to synthesise complex information on environmental chemistry and injurious effects of pollutants into predicted harmful impact on health of sentinel animals...
  15. ncbi A computational model of the digestive gland epithelial cell of marine mussels and its simulated responses to oil-derived aromatic hydrocarbons
    Michael N Moore
    Plymouth Marine Laboratory, UK
    Mar Environ Res 54:579-84. 2002
    ..The major response to AHs is induction of increased autophagy in these cells. Simulations indicate that the reactions to AHs and food deprivation correspond well with responses measured in vivo...
  16. ncbi Lysosomes and autophagy in aquatic animals
    Michael N Moore
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, United Kingdom
    Methods Enzymol 451:581-620. 2008
    ..Finally, coupled measurement of lysosomal-autophagic reactions and simulation modelling is proposed as a practical toolbox for predicting toxic environmental risk...
  17. ncbi A carbon and nitrogen flux model of mussel digestive gland epithelial cells and their simulated response to pollutants
    A McVeigh
    Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK
    Mar Environ Res 58:821-7. 2004
    ..Only the major physiological pathways relevant to the flow of either carbon or nitrogen or volume are modelled. Simulated response to hydrocarbon exposure is examined...
  18. ncbi Editorial: computational modelling of cell & tissue processes & function
    Michael N Moore
    J Mol Histol 35:655-8. 2004
    ....