Research Topics
| Bijay VaidyaSummaryAffiliation: Peninsula Medical School Country: UK Publications
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Detail Information
Publications
Severe hypothyroidism after thalidomide treatmentNicola de Savary
Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK
J R Soc Med 97:443. 2004
Management of hypothyroidism in adultsBijay Vaidya
Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter
BMJ 337:a801. 2008
Phenotypic multiple endocrine neoplasia type 2B, without endocrinopathy or RET gene mutation: implications for managementGill Spyer
Department of Endocrinology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, United Kingdom
Thyroid 16:605-8. 2006..We suggest that prophylactic thyroidectomy is unnecessary in these patients although they should still be screened for endocrinopathy on a regular basis...
Detection of thyroid dysfunction in early pregnancy: Universal screening or targeted high-risk case finding?Bijay Vaidya
Department of Endocrinology, Royal Devon, Exeter Hospital, Exeter EX2 5DW, United Kingdom
J Clin Endocrinol Metab 92:203-7. 2007....
Radioiodine treatment for benign thyroid disorders: results of a nationwide survey of UK endocrinologistsBijay Vaidya
Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter, UK
Clin Endocrinol (Oxf) 68:814-20. 2008..As there have been significant advances in the field since that survey, we carried out another survey to study the prevalent practices relating to radioiodine therapy for benign thyroid disorders across the UK...
Analysis of peripheral blood T-cell subsets in active thyroid-associated ophthalmopathy: absence of effect of octreotide-LAR on T-cell subsets in patients with thyroid-associated ophthalmopathyBijay Vaidya
Department of Endocrinology, Newcastle University, Newcastle upon Tyne, United Kingdom
Thyroid 15:1073-8. 2005..These results support a role of T cell in the pathogenesis of TAO, and show that octreotide-LAR has no effect on T-cell subsets during 32-weeks of treatment...
Treatment and screening of hypothyroidism in pregnancy: results of a European surveyBijay Vaidya
Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter, UK
Eur J Endocrinol 166:49-54. 2012..Therefore, we have carried out a survey of members of the European Thyroid Association (ETA) to study current practices relating to the management of hypothyroidism in pregnancy...
Fetal thyroid hormone level at birth is associated with fetal growthBeverley M Shields
Peninsula National Institute for Health Research Clinical Research Facility, Peninsula Medical School, University of Exeter, Exeter EX2 5DW, United Kingdom
J Clin Endocrinol Metab 96:E934-8. 2011..Overt maternal and fetal thyroid disorders are associated with reduced birth weight. We hypothesized that, even in the absence of overt thyroid dysfunction, maternal and fetal thyroid function influence fetal growth...
Cigarette smoking during pregnancy is associated with alterations in maternal and fetal thyroid functionBeverley Shields
Department of Endocrinology, Peninsula Medical School, Royal Devon, Exeter Hospital, Exeter EX2 5DW, United Kingdom
J Clin Endocrinol Metab 94:570-4. 2009..Studies in the general population have shown lower serum TSH levels in smokers as compared with nonsmokers...
Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancyBeverley M Shields
Peninsula National Institute for Health Research Clinical Research Facility, Peninsula Medical School, Exeter University, Exeter EX2 5DW, United Kingdom
J Clin Endocrinol Metab 94:4608-12. 2009..We aimed to assess whether genetic variation in TSH due to the rs4704397 genotype affects the number of individuals classified as having subclinical hypothyroidism in pregnancy...
Pituitary apoplexy within a macroprolactinomaAlastair Watt
A Watt is Acting Consultant Endocrinologist at the Department of Endocrinology, Royal Devon and Exeter Hospital, Exeter, UK
Nat Clin Pract Endocrinol Metab 4:635-41. 2008..MRI scan revealed a huge pituitary adenoma containing hemorrhage. Subsequent pituitary function tests indicated a grossly elevated serum prolactin level and hypopituitarism...
What is the evidence behind the evidence-base? The premature death of block-replace antithyroid drug regimens for Graves' diseaseSalman Razvi
Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
Eur J Endocrinol 154:783-6. 2006....
Quality of life in thyroid eye disease: impact of quality of careStephanie Estcourt
Department of Endocrinology Ophthalmology, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK
Eur J Endocrinol 164:649-55. 2011..It is hoped that recent initiatives, including the Amsterdam declaration, to raise the quality of care for patients with TED will help to improve their QOL...
The patient experience of services for thyroid eye disease in the United Kingdom: results of a nationwide surveyStephanie Estcourt
Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter EX2 5DW, UK
Eur J Endocrinol 161:483-7. 2009..A recent consensus statement from the European Group on Graves' Orbitopathy recommends referring all patients with thyroid eye disease (TED), except the mildest cases, to a specialist multidisciplinary clinic...
Analysis of gross deletions in the MEN1 gene in patients with multiple endocrine neoplasia type 1Martina Owens
Department of Molecular Genetics, Royal Devon and Exeter Hospital, Peninsula Medical School, Exeter, UK
Clin Endocrinol (Oxf) 68:350-4. 2008..Some of these patients may have gross gene deletions not detected by direct DNA sequencing or mutations in the noncoding regions of the gene not examined routinely...
Treatment for primary hypothyroidism: current approaches and future possibilitiesAli J Chakera
Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter
Drug Des Devel Ther 6:1-11. 2012..This review explores the historical and current treatment options for hypothyroidism, reasons for and potential solutions to suboptimal treatment, and future possibilities in the treatment of hypothyroidism...
Pituitary apoplexy: a review of clinical presentation, management and outcome in 45 casesLatika Sibal
Department of Endocrinology, Newcastle University Teaching Hospitals, Newcastle upon Tyne, U.K
Pituitary 7:157-63. 2004..Conclusions: This large series suggests that the patients with classical pituitary apoplexy, who are without neuro-ophthalmic signs or exhibit mild and non-progressive signs, can be managed conservatively in the acute stage...
The emerging role of the CTLA-4 gene in autoimmune endocrinopathiesBijay Vaidya
Department of Diabetes, Endocrinology and Vascular Medicine, Peninsula Medical School, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK
Eur J Endocrinol 150:619-26. 2004..Here we review the genetic and functional analyses of the CTLA-4 locus in autoimmune endocrinopathies, and discuss the recent efforts in fine-mapping this locus...
A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronineVijay Panicker
Henry Wellcome Laboratories for Integrative Neurosciences and Endocrinology, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, United Kingdom
J Clin Endocrinol Metab 93:3075-81. 2008..We aimed to thoroughly examine the role of common variation across the three deiodinase genes in relation to thyroid hormones...
Double-blind, placebo-controlled trial of octreotide long-acting repeatable (LAR) in thyroid-associated ophthalmopathyA Jane Dickinson
Department of Ophthalmology, Royal Victoria Infirmary, Newcastle on Tyne NE1 4LP, United Kingdom
J Clin Endocrinol Metab 89:5910-5. 2004..The improvements in both treated and placebo groups emphasize that the results of open studies must be viewed with caution...
Four pedigrees of the cation-leaky hereditary stomatocytosis class presenting with pseudohyperkalaemia. Novel profile of temperature dependence of Na+-K+ leak in a xerocytic formD M Gore
Department of Medicine, University College London, Rayne Institute, London, UK
Br J Haematol 125:521-7. 2004..Both of these latter two forms have previously been seen in other pedigrees. The first variant represents a novel kind of temperature dependence of the passive leak found in these pedigrees presenting with pseudohyperkalaemia...
