Research Topics
Genomes and Genes | A GreenfieldSummaryAffiliation: National Institute for Medical Research Country: UK Publications
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Publications
Novel gene expression patterns along the proximo-distal axis of the mouse embryo before gastrulationStephen Frankenberg
The Wellcome Trust Cancer Research UK Gurdon Institute of Cancer and Developmental Biology, Tennis Court Rd, Cambridge, UK
BMC Dev Biol 7:8. 2007..5. At E5.5, prospective anterior markers are expressed at the distal tip of the embryo, whereas prospective posterior markers are expressed more proximally, close to the boundary with the extraembryonic region...
An H-YDb epitope is encoded by a novel mouse Y chromosome geneA Greenfield
Centre for Molecular and Cellular Biology, University of Queensland, Brisbane, Australia
Nat Genet 14:474-8. 1996..We identify the peptide WMHHNMDLI derived from the UTY protein as an H-Y epitope, H-YDb. Our data formally demonstrate that H-Y antigen is the product of more than one gene on the Y chromosome...
The UTX gene escapes X inactivation in mice and humansA Greenfield
Centre for Molecular and Cellular Biology and Department of Anatomical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia
Hum Mol Genet 7:737-42. 1998..The human UTX gene was also found to be expressed from Xi. We discuss the significance of these data for our understanding of dosage compensation of X-Y homologous genes in humans and mice...
The Sry-related gene Sox18 maps to distal mouse chromosome 2A Greenfield
Centre for Molecular and Cellular Biology, University of Queensland, Brisbane, Australia
Genomics 36:558-9. 1996
The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryosE Wright
Centre for Molecular and Cellular Biology, University of Queensland, Brisbane, Australia
Nat Genet 9:15-20. 1995..The expression pattern and chromosomal location of Sox9 suggest that it may be the gene defective in the mouse skeletal mutant Tail-short, a potential animal model for campomelic dysplasia...
Molecular phenotyping of the mouse ky mutant reveals UCP1 upregulation at the neuromuscular junctions of dystrophic soleus muscleG Blanco
MRC Mammalian Genetics Unit and UK Mouse Genome Centre, Harwell, Oxon OX11 ORD, UK
Neuromuscul Disord 14:217-28. 2004..Altogether, the data presented suggest that the ky muscular dystrophy develops by a distinctive pathogenic mechanism...
Expression of a linear Sry transcript in the mouse genital ridgeY W Jeske
Centre for Molecular and Cellular Biology, University of Queensland, Brisbane, Australia
Nat Genet 10:480-2. 1995..The spatial and temporal profile of Sry expression suggests that its role in the mouse fetus is limited to initiating Sertoli cell development during testis determination...
Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual developmentS Grimmond
MRC Mammalian Genetics Unit, Harwell, UK
Hum Mol Genet 9:1553-60. 2000....
The mouse Y chromosome interval necessary for spermatogonial proliferation is gene dense with syntenic homology to the human AZFa regionS Mazeyrat
INSERM U491, Faculte de Medecine, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 5, France
Hum Mol Genet 7:1713-24. 1998..Our results therefore show that AZFa and Spy may be encoded by homologous genes...
Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanismsD Grbavec
Center for Neuronal Survival, Montreal Neurological Institute, 3801 rue University, Montreal, Quebec, H3A 2B4 Canada
Biochem J 337:13-7. 1999..These findings suggest that mammalian TLE and UTY/X proteins may mediate repression mechanisms similar to those performed by TUP1-SSN6 in yeast...
Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1)S Grimmond
MRC Mammalian Genetics Unit, Harwell, OX11 0RD, United Kingdom
Genomics 70:74-81. 2000..We discuss the possible functions of this novel gene and its role in heritable disease in light of these data...
Expression of a novel mammalian epidermal growth factor-related gene during mouse neural developmentS Grimmond
MRC Mammalian Genetics Unit, Harwell, OX11 0RD, Didcot, UK
Mech Dev 102:209-11. 2001..Scube2 transcription is restricted to the embryonic neurectoderm but is also detectable in the adult heart, lung and testis...
