Research Topics
Species | Richard BaldockSummaryAffiliation: National Institute for Medical Research Country: UK Publications
| Collaborators
|
Detail Information
Publications
Optical projection tomography as a tool for 3D microscopy and gene expression studiesJames Sharpe
Medical Research Council, Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
Science 296:541-5. 2002..OPT microscopy allows the rapid mapping of the tissue distribution of RNA and protein expression in intact embryos or organ systems and can therefore be instrumental in studies of developmental biology or gene function...- 3 dimensional modelling of early human brain development using optical projection tomographyJanet Kerwin
Institute of Human Genetics, University of Newcastle upon Tyne, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK
BMC Neurosci 5:27. 2004..We have assessed the resolution of unstained neuronal structures within a Carnegie Stage (CS)17 OPT model and tested its use as a framework onto which anatomical structures can be defined and gene expression data mapped... - The Mouse Limb Anatomy Atlas: an interactive 3D tool for studying embryonic limb patterningApril DeLaurier
Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, London, UK
BMC Dev Biol 8:83. 2008..Existing textual references consist of two-dimensional (2D) illustrations of the adult rat or mouse limb that can be difficult to apply when attempting to describe the complex three-dimensional (3D) relationship between tissues... - Biomedical atlases: systematics, informatics and analysisRichard A Baldock
MRC Human Genetics Unit, MRC Institute of Genetic and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, UK
Adv Exp Med Biol 736:655-77. 2012.... - Anatomical ontologies: names and places in biologyRichard Baldock
Medical Research Council, Human Genetics Unit, Edinburgh EH4 2XU, UK
Genome Biol 6:108. 2005..In bioinformatics, ontologies might allow hitherto impossible query and data-mining activities. We review the use of anatomy ontologies to represent space in biological organisms, specifically mouse and human... - EMAP and EMAGE: a framework for understanding spatially organized dataRichard A Baldock
MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh, UK
Neuroinformatics 1:309-25. 2003.... - JAtlasView: a Java atlas-viewer for browsing biomedical 3D images and atlasesGuangjie Feng
MRC Human Genetics Unit, Western General Hospital, Crewe Road, EH4 2XU, Edinburgh, UK
BMC Bioinformatics 6:47. 2005..Here we discuss an atlas viewer implemented to run on any workstation using the architecture neutral Java programming language... - Integrating partonomic hierarchies in anatomy ontologiesAlbert Burger
MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
BMC Bioinformatics 5:184. 2004..This raises the issue of how to represent and integrate multiple such hierarchies... - Formalization of mouse embryo anatomyAlbert Burger
MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK
Bioinformatics 20:259-67. 2004..As part of this database, a mouse embryo anatomy ontology has been created. A formalization of this anatomy is required to document its precise semantics and how it is used in the context of the Mouse Atlas... - The BioMart interface to the eMouseAtlas gene expression database EMAGEPeter Stevenson
The Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
Database (Oxford) 2011:bar029. 2011..The federated nature of BioMart allows scope for integration and cross querying of EMAGE with other similar BioMarts... - A scalable mediator approach to process large biomedical 3-D imagesKonstantinos Liakos
MRC Human Genetics Unit, Western Hospital, Edinburgh EH4 2X0, U K
IEEE Trans Inf Technol Biomed 8:354-9. 2004..The system's data are distributed and/or declustered across a number of image servers and are processed by specialized mediators... - A criticality-based framework for task composition in multi-agent bioinformatics integration systemsKonstantinos A Karasavvas
School of Mathematical and Computer Sciences, Heriot Watt University Edinburgh EH14 4AS, UK
Bioinformatics 21:3155-63. 2005..We propose an agent architecture, and a concrete bioinformatics example (prototype) is used to show how certain decisions may not be critical in the context of more complex tasks... - An ontology of human developmental anatomyAmy Hunter
Bioinformatics Group, Division of Biomedical Sciences, Hugh Robson Building, University of Edinburgh, UK
J Anat 203:347-55. 2003..The third gives the second version in GO ontology syntax (with standard IDs for each tissue) and can be downloaded from both the genex and the Open Biological Ontology sites (http://obo.sourceforge.net/)... - 3D modelling, gene expression mapping and post-mapping image analysis in the developing human brainSubrot Sarma
Institute of Human Genetics, University of Newcastle, Central Parkway, UK
Brain Res Bull 66:449-53. 2005.... - Data integration in eHealth: a domain/disease specific roadmapJenny Ure
Generation Scotland
Stud Health Technol Inform 126:144-53. 2007..It outlines emerging strategies, recommendations and objectives for collaboration on shared ontology-building and harmonization of data for multi-site trials in this domain... - The European dimension for the mouse genome mutagenesis programJohan Auwerx
Mouse Clinical Institute (MCI, Illkirch, Strasbourg, France [corrected
Nat Genet 36:925-7. 2004..The combined efforts will accelerate our understanding of gene function and of human health and disease...