Research Topics
| N A MaskellSummaryCountry: UK Publications
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Detail Information
Publications
Mannose-binding lectin genotypes: lack of association with susceptibility to thoracic empyemaStephen J Chapman
The Wellcome Trust Centre for Human Genetics, University of Oxford, UK
BMC Med Genet 11:5. 2010..The possible role of MBL genotypic deficiency in susceptibility to thoracic empyema has not previously been reported...
Diagnostically significant variations in pleural fluid pH in loculated parapneumonic effusionsNick A Maskell
Oxford Centre for Respiratory Medicine, Churchill Hospital, John Radcliffe NHS Trust, Oxford, Oxfordshire, UK
Chest 126:2022-4. 2004..We therefore set out to test the hypothesis that pH varies significantly between locules in complicated parapneumonic effusions...
Randomized trials describing lung inflammation after pleurodesis with talc of varying particle sizeNick A Maskell
Oxford Pleural Disease Clinic, Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford Radcliffe NHS Trust, Oxford OX3 7LJ, UK
Am J Respir Crit Care Med 170:377-82. 2004..46 kPa 5.4 18.5 mm Hg, difference = 1.45; 95% CI, 0.2 to 2.7; p = 0.03) and induced more systemic inflammation than graded talc. We conclude that the routine use of graded talc for pleurodesis would reduce the morbidity of this procedure...
Variations in experience in obtaining local ethical approval for participation in a multi-centre studyN A Maskell
Oxford Centre for Respiratory Medicine, Churchill Hospital, John Radcliffe NHS Trust, Headington, Oxford, UK
QJM 96:305-7. 2003..This process is intended as a rapid standardized approval process, facilitating the execution of clinical trials...
BTS guidelines for the investigation of a unilateral pleural effusion in adultsN A Maskell
Oxford Centre for Respiratory Medicine, Churchill Hospital Site, Oxford Radcliffe Hospital, Headington, Oxford OX3 7LJ, UK
Thorax 58:ii8-17. 2003
Standard pleural biopsy versus CT-guided cutting-needle biopsy for diagnosis of malignant disease in pleural effusions: a randomised controlled trialN A Maskell
Respiratory Trials Unit, Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford Radcliffe NHS Trust, OX3 7LJ, Oxford, UK
Lancet 361:1326-30. 2003..Pleural biopsy needs to be done in the remaining cases. We aimed to assess whether CT-guided biopsy is an improvement over standard pleural biopsy in this setting...
Images in clinical medicine. Effect of intrapleural streptokinase on a loculated malignant pleural effusionN A Maskell
Churchill Hospital, Headington, Oxford OX3 7LJ, United Kingdom
N Engl J Med 348:e4. 2003
Asymptomatic carriage of Pneumocystis jiroveci in subjects undergoing bronchoscopy: a prospective studyN A Maskell
Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford Radcliffe NHS Trust, Oxford OX3 7LJ, UK
Thorax 58:594-7. 2003..The higher prevalence in patients receiving corticosteroids suggests that oral glucocorticoid therapy is an independent risk factor for colonisation. In contrast, underlying lung cancer or COPD did not appear to be risk factors...
A randomized controlled trial of adaptive ventilation for Cheyne-Stokes breathing in heart failureJustin C T Pepperell
Oxford Sleep Unit, Oxford Centre for Respiratory Medicine, Oxford Radcliffe Hospital, Oxford, United Kingdom
Am J Respir Crit Care Med 168:1109-14. 2003..This study suggests improvements in neurohormonal activation with this treatment...
A national survey of oncologist and chest physicians' attitudes towards empirical anti-oestrogen therapy, early pleurodesis and preference of sclerosing agent in malignant breast and ovarian pleural diseaseAndrew R L Medford
Palliat Med 19:430-1. 2005
Pleurodesis practice for malignant pleural effusions in five English-speaking countries: survey of pulmonologistsY C Gary Lee
University of Oxford and Osler Chest Unit, Churchill Hospital, Oxford OX3 7BN, UK
Chest 124:2229-38. 2003..Pleurodesis is important in the management of malignant pleural effusions, but no consensus exists on the optimal agent or methods of pleurodesis. How pleurodesis is practiced worldwide has not been studied...
The bacteriology of pleural infection by genetic and standard methods and its mortality significanceNick A Maskell
Department of Respiratory Medicine, Southmead Hospital, North Bristol NHS Trust, UK
Am J Respir Crit Care Med 174:817-23. 2006..Antibiotics for community-acquired infection should treat aerobic and anaerobic bacteria. Hospital-acquired, gram-negative S. aureus and mixed aerobic infections have a high mortality rate...
