Research Topics
| M RowlandSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
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Detail Information
Publications
Control of pyrethroid-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes with chlorfenapyr in BeninRaphael N'Guessan
London School of Hygiene and Tropical Medicine, London, UK
Trop Med Int Health 14:389-95. 2009..To compare the efficacy of chlorfenapyr applied on mosquito nets and as an indoor residual spray against populations of Anopheles gambiae and Culex quinquefasciatus in an area of Benin that shows problematic levels of pyrethroid resistance...- Biochemical basis of permethrin resistance in Anopheles arabiensis from Lower Moshi, north-eastern TanzaniaJohnson Matowo
Pan African Malaria Vector Research Consortium www pamverc org
Malar J 9:193. 2010..In this study, metabolic-based mechanisms conferring permethrin (pyrethroid) resistance were investigated in Anopheles arabiensis of Lower Moshi, Kilimanjaro region of north-eastern Tanzania... - Field trial of three different Plasmodium vivax-detecting rapid diagnostic tests with and without evaporative cool box storage in AfghanistanAmy F W Mikhail
London School of Hygiene and Tropical Medicine, London, UK
Malar J 10:169. 2011..The potential for locally made evaporative cooling boxes (ECB) to protect the tests from heat damage in high summer temperatures was also investigated... - Clinical trial of extended-dose chloroquine for treatment of resistant falciparum malaria among Afghan refugees in PakistanNatasha Howard
London School of Hygiene and Tropical Medicine, London, UK
Malar J 10:171. 2011..An in-vivo randomized controlled trial was conducted among refugees with uncomplicated falciparum malaria to determine whether five-day treatment (CQ40) was more effective than standard treatment (CQ25)... - Malaria risk factors in north-east TanzaniaPeter Winskill
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
Malar J 10:98. 2011..Malaria ecology in Tanzania appears to have reduced over recent years. This study investigated potential risk factors and clustering in face of changing infection dynamics... - The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malariaSue J Lee
Mahidol Oxford Tropical Medicine Research Unit MORU, Mahidol University, Faculty of Tropical Medicine, 3rd Floor, 60th Anniversary Chalermprakiat Building, 420 6 Ratchawithi Rd, Ratchathewi District, Bangkok 10400, Thailand
Malar J 7:149. 2008..Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For comparisons across studies, it is often necessary to derive one measure from the other... - An experimental hut evaluation of Olyset nets against anopheline mosquitoes after seven years use in Tanzanian villagesRobert C Malima
London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
Malar J 7:38. 2008..It has not been determined for how long Olyset nets remain protective against mosquitoes in household use... - Evaluation of PermaNet 3.0 a deltamethrin-PBO combination net against Anopheles gambiae and pyrethroid resistant Culex quinquefasciatus mosquitoes: an experimental hut trial in TanzaniaPatrick Tungu
Amani Medical Research Centre, National Institute for Medical Research, Muheza, Tanzania
Malar J 9:21. 2010..PBO is an inhibitor of mixed function oxidases implicated in pyrethroid resistance... - Experimental hut evaluation of bednets treated with an organophosphate (chlorpyrifos-methyl) or a pyrethroid (lambdacyhalothrin) alone and in combination against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoesAlex N Asidi
London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
Malar J 4:25. 2005..Certain compounds of an earlier generation of insecticides, the organophosphates may have potential as net treatments... - Subsidized sales of insecticide-treated nets in Afghan refugee camps demonstrate the feasibility of a transition from humanitarian aid towards sustainabilityJan H Kolaczinski
HealthNet International, University Town, P, O, Box 889, Peshawar, Pakistan
Malar J 3:15. 2004..Here we outline the strategy and document the progress to provide guidance for replication of similar approaches in other chronic refugee situations... - Evaluation of KO-Tab 1-2-3: a wash-resistant 'dip-it-yourself' insecticide formulation for long-lasting treatment of mosquito netsAlison Yates
London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
Malar J 4:52. 2005..Bayer Environmental Science (BES) has developed a long-lasting formulation 'KO-Tab 1-2-3' which can be applied to the net post-manufacture, under field conditions, and renders the insecticide wash-resistant... - Malaria control under the Taliban regime: insecticide-treated net purchasing, coverage, and usage among men and women in eastern AfghanistanNatasha Howard
London School of Hygiene and Tropical Medicine, London, UK
Malar J 9:7. 2010..This strengthens the knowledge base on household-level health choices in complex-emergency settings... - Tents pre-treated with insecticide for malaria control in refugee camps: an entomological evaluationKate Graham
HealthNet International, Peshawar, Pakistan
Malar J 3:25. 2004..A refugee shelter that is treated with insecticide during manufacture would be useful for malaria control at the acute stage of an emergency, when logistic problems, poor co-ordination and insecurity limit the options for malaria control... - Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA methodManisha A Kulkarni
Department of Natural Resource Sciences, McGill University, Macdonald Campus, Ste Anne de Bellevue, Quebec H9X 3V9, Canada
Malar J 5:56. 2006..Knockdown resistance (kdr) confers resistance to the pyrethroid class of insecticides with cross-resistance to DDT through single nucleotide polymorphisms (SNPs) in the voltage-gated sodium channel gene... - Control of pyrethroid and DDT-resistant Anopheles gambiae by application of indoor residual spraying or mosquito nets treated with a long-lasting organophosphate insecticide, chlorpyrifos-methylRaphael N'Guessan
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
Malar J 9:44. 2010..Dow Agrosciences have developed a microencapsulated formulation (CS) of the organophosphate chlorpyrifos methyl as a cost-effective, long-lasting alternative to DDT... - DEET mosquito repellent provides personal protection against malaria: a household randomized trial in an Afghan refugee camp in PakistanMark Rowland
HealthNet International, Peshawar, Pakistan
Trop Med Int Health 9:335-42. 2004..There is a case for giving repellents more prominence in public health as a preventive measure in regions where vectors bite in the early evening or in emergency situations such as epidemics or newly established refugee camps... - DEET mosquito repellent sold through social marketing provides personal protection against malaria in an area of all-night mosquito biting and partial coverage of insecticide-treated nets: a case-control study of effectivenessMark Rowland
HealthNet International, University Town, Peshawar, Pakistan
Trop Med Int Health 9:343-50. 2004..It was shown that Mosbar prevented biting throughout this period. In regions where mosquito vectors bite during evening and night, repellents could have a useful supplementary role to ITN and their use should be more widely encouraged... - Combining indoor residual spraying with chlorfenapyr and long-lasting insecticidal bed nets for improved control of pyrethroid-resistant Anopheles gambiae: an experimental hut trial in BeninCorine Ngufor
London School of Hygiene and Tropical Medicine, London, UK
Malar J 10:343. 2011..The combining of IRS and LLINs presents an opportunity for improved control and management of pyrethroid resistance through the simultaneous presentation of unrelated insecticides... - Anopheline vectors and malaria transmission in eastern AfghanistanMark Rowland
HealthNet International, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 96:620-6. 2002..The conventional view of A. culicifacies being the main rural vector and A. stephensi important only in urban settings needs to be reconsidered in western outreaches of the Indo-Pakistan subcontinent... - Afghan refugees and the temporal and spatial distribution of malaria in PakistanMark Rowland
HealthNet International, University Town, Peshawar, Pakistan
Soc Sci Med 55:2061-72. 2002..These trends indicate that the burden would continue to fall if political conditions in Afghanistan were to improve and more refugees returned to their homeland... - Prevention of malaria in Afghanistan through social marketing of insecticide-treated nets: evaluation of coverage and effectiveness by cross-sectional surveys and passive surveillanceMark Rowland
HealthNet International, Peshawar, Pakistan London School of Hygiene and Tropical Medicine, UK
Trop Med Int Health 7:813-22. 2002..The abundance of Anopheles stephensi, the main vector, did not appear to be affected by ITN. ITN constitute one of the few feasible options for protection against malaria in chronic emergencies... - Malaria epidemiology and control in refugee camps and complex emergenciesM Rowland
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Ann Trop Med Parasitol 95:741-54. 2001..United Nations' humanitarian and non-governmental agencies can play a significant part in resolving the outstanding research issues in malaria control... - Control of malaria in Pakistan by applying deltamethrin insecticide to cattle: a community-randomised trialM Rowland
HealthNet International, University Town, Peshawar, Pakistan
Lancet 357:1837-41. 2001..We aimed to investigate whether domestic livestock treated with deltamethrin (applied by a sponging method) would prove toxic to mosquitoes and therefore aid in malaria control... - Permethrin-treated chaddars and top-sheets: appropriate technology for protection against malaria in Afghanistan and other complex emergenciesM Rowland
HealthNet International, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 93:465-72. 1999..In Islamic and non-Islamic countries in Asia, treated chaddars and top-sheets should offer a satisfactory solution for the most vulnerable who cannot afford treated nets... - Sustainability of pyrethroid-impregnated bednets for malaria control in Afghan communitiesM Rowland
HealthNet International, Peshawar, North West Frontier Province, Pakistan
Bull World Health Organ 75:23-9. 1997.... - Comparison of three pyrethroid treatments of top-sheets for malaria control in emergencies: entomological and user acceptance studies in an Afghan refugee camp in PakistanK Graham
HealthNet International, Peshawar, Pakistan
Med Vet Entomol 16:199-206. 2002..Side-effects associated with deltamethrin indicate that alphacypermethrin and permethrin are more appropriate first choice insecticides for treatment of sheets and blankets... - Insecticide-treated plastic tarpaulins for control of malaria vectors in refugee campsK Graham
HealthNet International, Peshawar, Pakistan
Med Vet Entomol 16:404-8. 2002..Mass coverage with deltamethrin-sprayed or impregnated tarpaulins or tents has strong potential for preventing malaria in displaced populations affected by conflict... - Sulfadoxine-pyrimethamine plus artesunate compared with chloroquine for the treatment of vivax malaria in areas co-endemic for Plasmodium falciparum and P. vivax: a randomised non-inferiority trial in eastern AfghanistanKate Kolaczinski
HealthNet TPO, P O Box 8011, University Town, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 101:1081-7. 2007..In areas where vivax infections might be misdiagnosed as falciparum infections and treated with SP+AS, patient management would be as good, or better than, with the standard CQ treatment... - High altitude epidemic malaria in Bamian province, central AfghanistanM Abdur Rab
HealthNet International, Peshawar, Pakistan
East Mediterr Health J 9:232-9. 2003..The outbreak led to severe morbidity and high mortality in a province having only a few poorly-provisioned health care facilities... - Socio-economic factors associated with the purchasing of insecticide-treated nets in Afghanistan and their implications for social marketingNatasha Howard
HealthNet International, University Town, Peshawar, Pakistan
Trop Med Int Health 8:1043-50. 2003..In conflict affected countries where livelihoods are compromised, it is necessary to target subsidies at the most impoverished to make ITN affordable and to improve overall coverage... - Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in AfghanistanNaeem Durrani
HealthNet International, Malaria and Leishmaniasis Control Programme, University Town, Peshawar, Pakistan
Trop Med Int Health 10:521-9. 2005..An alternative drug combination to AQ/AS is required for Afghanistan... - Randomized controlled trials of 5- and 14-days primaquine therapy against relapses of vivax malaria in an Afghan refugee settlement in PakistanM Rowland
HealthNet International, University Town, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 93:641-3. 1999..In extended tests in vivo in which vivax cases (n = 31) were treated with chloroquine 25 mg/kg and 14-days primaquine, there was no parasite recrudescence within 28 days and hence no evidence of resistance to chloroquine... - Comparison of the OptiMAL rapid antigen test with field microscopy for the detection of Plasmodium vivax and P. falciparum: considerations for the application of the rapid test in AfghanistanJ Kolaczinski
Health Net International, 11 A Circular Lane, PO Box 889, University Town, Peshawar, Pakistan
Ann Trop Med Parasitol 98:15-20. 2004..Rapid antigen tests are more suited to investigations of outbreaks in remote situations, where health services are deficient or absent... - An outbreak of cutaneous leishmaniasis in an Afghan refugee settlement in north-west PakistanM Rowland
HealthNet International, University Town, Pakistan
Trans R Soc Trop Med Hyg 93:133-6. 1999..The Afghanistan capital, Kabul, is currently experiencing a major epidemic of CL; infected migrant carriers from Kabul are probably the source of the outbreak in Timargara... - Chlorfenapyr: a pyrrole insecticide for the control of pyrethroid or DDT resistant Anopheles gambiae (Diptera: Culicidae) mosquitoesP Boko
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Acta Trop 102:69-78. 2007..For treated-net applications chlorfenapyr might be combined with pyrethroid as a mixture to provide personal protection as well as to give control of resistant mosquitoes... - Refugee health in the tropics. Malaria control in Afghan refugee camps: novel solutionsM Rowland
HealthNet International, P O Box 889, University Town, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 95:125-6. 2001..The range of interventions applied in Afghan refugee camps, the factors influencing choice and the relevance to emergencies in other parts of the world are described... - Mosquitoes and bednets: testing the spatial positioning of insecticide on nets and the rationale behind combination insecticide treatmentsR M Oxborough
Kilimanjaro Christian Medical Centre, PO Box 3010, Moshi, Tanzania
Ann Trop Med Parasitol 102:717-27. 2008.... - Epidemic of Plasmodium falciparum malaria involving substandard antimalarial drugs, Pakistan, 2003Toby Leslie
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
Emerg Infect Dis 15:1753-9. 2009..However, chemical analysis of the drug showed that it was substandard. As global incidence decreases and epidemics become more of a threat, enhanced quality assurance of control interventions is essential... - Scaling-up and sustaining insecticide-treated net coverageJo Lines
London School of Hygiene and Tropical Medicine, London, UK
Lancet Infect Dis 3:465-6; discussion 467-8. 2003 - A health facility based case-control study of effectiveness of insecticide treated nets: potential for selection bias due to pre-treatment with chloroquineJayne Webster
London School of Hygiene and Tropical Medicine, UK
Trop Med Int Health 8:196-201. 2003..Generalisation of results over a wide geographic region, or between urban and rural settings, may not be appropriate... - Epidemiology of anthroponotic cutaneous leishmaniasis in Afghan refugee camps in northwest PakistanJan Kolaczinski
HealthNet International, University Town, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 98:373-8. 2004..Based on the evidence from this study an intervention strategy was formulated for all camps with reported ACL cases. This includes targeting of active cases with insecticide-treated nets, sold at a highly subsidised price... - The impact of phenotypic and genotypic G6PD deficiency on risk of plasmodium vivax infection: a case-control study amongst Afghan refugees in PakistanToby Leslie
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS Med 7:e1000283. 2010..If the level of protection was sufficient, antirelapse therapy could become more widely available. We therefore tested the hypothesis that G6PD deficiency is protective against vivax malaria infection... - An experimental hut evaluation of PermaNet(®) 3.0, a deltamethrin-piperonyl butoxide combination net, against pyrethroid-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes in southern BeninRaphael N'Guessan
London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E7HT, UK
Trans R Soc Trop Med Hyg 104:758-65. 2010..Against C. quinquefasciatus, no treatment killed >24% entering the huts. The synergism from unwashed PermaNet 3.0 was lower than expected, probably due to an unidentified resistance mechanism unaffected by PBO... - Malaria control in Afghanistan: progress and challengesJan Kolaczinski
Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, UK
Lancet 365:1506-12. 2005..This process should be guided by the knowledge and experience gained during the complex emergency and a focus on malaria should be maintained until the disease is brought under control... - Evaluation of indoxacarb, an oxadiazine insecticide for the control of pyrethroid-resistant Anopheles gambiae (Diptera: Culicidae)Raphael N'Guessan
London School of Hygiene and Tropical Medicine, Gates Malaria Partnership, London WC1E 7HT, United Kingdom
J Med Entomol 44:270-6. 2007..The absence of cross-resistance to current insecticides indicates that indoxacarb has malaria vector control potential as larvicide or adulticide where mosquitoes are pyrethroid resistant... - A randomised trial of an eight-week, once weekly primaquine regimen to prevent relapse of plasmodium vivax in Northwest Frontier Province, PakistanToby Leslie
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 3:e2861. 2008..Safe and effective use of PQ without the need for G6PD testing would be ideal. The efficacy and safety of an 8-week, once weekly PQ regimen was compared with current standard treatment (chloroquine alone) and a 14-day PQ regimen... - Spatial epidemiology of Plasmodium vivax, AfghanistanSimon Brooker
London School of Hygiene and Tropical Medicine, London, United Kingdom
Emerg Infect Dis 12:1600-2. 2006..Remote sensing enabled development of a risk map, thereby providing a valuable tool to help guide malaria control strategies... - Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the treatment of Plasmodium vivax malaria in Afghanistan and Pakistan: a randomized controlled trialToby Leslie
HealthNet TPO Malaria and Leishmaniasis Control Programme, Peshawar, Northwest Frontier Province, Pakistan
JAMA 297:2201-9. 2007..The antifolates are an important and affordable antimalarial class to which it is often assumed P vivax malaria is intrinsically resistant... - DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectorsRaphael N'Guessan
London School of Hygiene and Tropical Medicine, London, UK
Trans R Soc Trop Med Hyg 102:259-62. 2008..Such formulations may have the potential for use on nets against pyrethroid-resistant mosquitoes or on clothing or bedding materials distributed in disasters, emergencies or refugee camp situations... - Evaluation of synthetic repellents on mosquito nets in experimental huts against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoesRaphael N'Guessan
Gates Malaria Partnership, London School of Hygiene and Tropical Medicine, 50 Bedford Square, London, UK
Trans R Soc Trop Med Hyg 100:1091-7. 2006..The DEET-based product provided better and longer protection; tunnel test bioassays confirmed that residual activity lasted for up to 6 weeks. Application of repellents to nets warrants further investigation and development... - Amodiaquine resistance in Plasmodium falciparum malaria in Afghanistan is associated with the pfcrt SVMNT allele at codons 72 to 76Khalid Beshir
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
Antimicrob Agents Chemother 54:3714-6. 2010..We provide in vivo data to support the in vitro correlation between pfcrt SVMNT and increased resistance to the metabolite of amodiaquine... - Compliance with 14-day primaquine therapy for radical cure of vivax malaria--a randomized placebo-controlled trial comparing unsupervised with supervised treatmentToby Leslie
HealthNet International, Peshawar, Pakistan
Trans R Soc Trop Med Hyg 98:168-73. 2004..Unsupervised treatment with 14-day PQ when combined with simple instruction can avert a significant amount of the morbidity associated with relapse in populations where G6PD deficiency is either absent or readily diagnosable... - Efficacy of pyrethroid-treated nets against malaria vectors and nuisance-biting mosquitoes in Tanzania in areas with long-term insecticide-treated net useManisha A Kulkarni
Department of Natural Resource Sciences, McGill University, Ste Anne de Bellevue, QC, Canada
Trop Med Int Health 12:1061-73. 2007..To measure pyrethroid susceptibility in populations of malaria vectors and nuisance-biting mosquitoes in Tanzania and to test the biological efficacy of current insecticide formulations used for net treatment... - MalariaChristopher J M Whitty
Gates Malaria Partnership, London School of Hygiene and Tropical Medicine, London WC1B 3DP
BMJ 325:1221-4. 2002 - Insecticide-treated netsJenny Hill
Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
Adv Parasitol 61:77-128. 2006.... - Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria control in pyrethroid resistance area, BeninVincent Corbel
London School of Hygiene and Tropical Medicine, Cotonou, Benin, West Africa
Emerg Infect Dis 13:199-206. 2007..Pyrethroid resistance in An. gambiae appears to threaten the future of ITN and IRS in Benin... - Leishmaniasis in refugee and local Pakistani populationsSimon Brooker
London School of Hygiene and Tropical Medicine, London, United Kingdom
Emerg Infect Dis 10:1681-4. 2004..Results suggested similar patterns of endemicity in both Afghan refugee and Pakistani populations and highlighted risk factors and household clustering of disease... - The Innovative Vector Control Consortium: improved control of mosquito-borne diseasesJanet Hemingway
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK, L3 5QA
Trends Parasitol 22:308-12. 2006.... - The prolonged epidemic of anthroponotic cutaneous leishmaniasis in Kabul, Afghanistan: 'bringing down the neighbourhood'Hugh Reyburn
HealthNet International, Kabul, Afghanistan
Trans R Soc Trop Med Hyg 97:170-6. 2003..As population movement is clearly a contributing factor to its transmission, this threat is very real...