M Molokhia

Summary

Affiliation: London School of Hygiene and Tropical Medicine
Country: UK

Publications

  1. ncbi Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006
    Mariam Molokhia
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 3:e2522. 2008
  2. ncbi Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005
    Hitesh Patel
    Charing Cross Hospital, London W6 8RF, UK
    BMC Clin Pharmacol 7:9. 2007
  3. ncbi Risk for rheumatic disease in relation to ethnicity and admixture
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK
    Arthritis Res 2:115-25. 2000
  4. ncbi 30 Year patterns of mortality in Tobago, West Indies, 1976-2005: impact of glucose intolerance and alcohol intake
    Mariam Molokhia
    Division of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 6:e14588. 2011
  5. ncbi Case ascertainment and estimated incidence of drug-induced long-QT syndrome: study in Southwest France
    Mariam Molokhia
    Non Communicable Disease Epidemiology UnitLondon School of Hygiene and Tropical MedicineKeppel Street, WC1E 7HT London, UK
    Br J Clin Pharmacol 66:386-95. 2008
  6. ncbi Cross-sectional analysis of adverse outcomes in 1,029 pregnancies of Afro-Caribbean women in Trinidad with and without systemic lupus erythematosus
    Mariam Molokhia
    Non communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Arthritis Res Ther 9:R124. 2007
  7. ncbi Systemic lupus erythematosus: genes versus environment in high risk populations
    M Molokhia
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Lupus 15:827-32. 2006
  8. ncbi FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans
    Mariam Molokhia
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Rheumatology (Oxford) 50:1206-10. 2011
  9. ncbi EUDRAGENE: European collaboration to establish a case-control DNA collection for studying the genetic basis of adverse drug reactions
    Mariam Molokhia
    London School of Hygiene and Tropical Medicine, Non communicable Disease Epidemiology Unit, Keppel Street, London, UK
    Pharmacogenomics 7:633-8. 2006
  10. ncbi Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Hum Genet 112:310-8. 2003

Collaborators

Detail Information

Publications18

  1. ncbi Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006
    Mariam Molokhia
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 3:e2522. 2008
    ....
  2. ncbi Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005
    Hitesh Patel
    Charing Cross Hospital, London W6 8RF, UK
    BMC Clin Pharmacol 7:9. 2007
    ..We examined trends in hospital admissions associated with adverse drug reaction in English hospitals and the accuracy of national reporting...
  3. ncbi Risk for rheumatic disease in relation to ethnicity and admixture
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK
    Arthritis Res 2:115-25. 2000
    ....
  4. ncbi 30 Year patterns of mortality in Tobago, West Indies, 1976-2005: impact of glucose intolerance and alcohol intake
    Mariam Molokhia
    Division of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 6:e14588. 2011
    ..To determine the main predictors of all-cause and cardiovascular (CV) mortality in a rural West Indian population in Plymouth, Tobago over 30 years...
  5. ncbi Case ascertainment and estimated incidence of drug-induced long-QT syndrome: study in Southwest France
    Mariam Molokhia
    Non Communicable Disease Epidemiology UnitLondon School of Hygiene and Tropical MedicineKeppel Street, WC1E 7HT London, UK
    Br J Clin Pharmacol 66:386-95. 2008
    ....
  6. ncbi Cross-sectional analysis of adverse outcomes in 1,029 pregnancies of Afro-Caribbean women in Trinidad with and without systemic lupus erythematosus
    Mariam Molokhia
    Non communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Arthritis Res Ther 9:R124. 2007
    ..There was some evidence of an increased risk of preterm delivery and ectopic pregnancy in pregnancies conceived after a diagnosis of maternal SLE...
  7. ncbi Systemic lupus erythematosus: genes versus environment in high risk populations
    M Molokhia
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Lupus 15:827-32. 2006
    ..Smoking, occupational exposures to silica and exposure to infection in childhood may explain some non-genetic risk factors for SLE in these groups...
  8. ncbi FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans
    Mariam Molokhia
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Rheumatology (Oxford) 50:1206-10. 2011
    ..To evaluate FCGR3B copy number variation (CNV) in African and European populations and to determine if FCGR3B copy number is associated with SLE and SLE nephritis risk in Afro-Caribbeans, adjusting for African genetic ancestry...
  9. ncbi EUDRAGENE: European collaboration to establish a case-control DNA collection for studying the genetic basis of adverse drug reactions
    Mariam Molokhia
    London School of Hygiene and Tropical Medicine, Non communicable Disease Epidemiology Unit, Keppel Street, London, UK
    Pharmacogenomics 7:633-8. 2006
    ..This will provide a basis for adverse drug susceptibility genome association-wide studies using tag single nucleotide polymorphisms, or a direct approach using putative functional polymorphisms...
  10. ncbi Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Hum Genet 112:310-8. 2003
    ..This conclusion lays a basis for localizing the genes underlying this ethnic difference in risk of SLE by admixture mapping...
  11. ncbi Systemic lupus erythematosus in migrants from west Africa compared with Afro-Caribbean people in the UK
    M Molokhia
    Epidemiology Unit, London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
    Lancet 357:1414-5. 2001
    ..The high prevalence of SLE in recent migrants from west Africa suggests that the disease is not rare in west Africa, and that there is a genetic basis for the high risk of SLE in people of west African descent compared with other groups...
  12. ncbi Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials
    Dorothea Nitsch
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Epidemiol 163:397-403. 2006
    ..However, care must be taken, because drawing valid causal inferences from its application depends upon more extensive assumptions than are required in randomized controlled trials...
  13. ncbi Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy
    P H Dixon
    Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK
    Gut 58:537-44. 2009
    ..ABCB11 encodes the bile salt export pump (BSEP); mutations cause a spectrum of cholestatic disease, and are implicated in the aetiology of ICP...
  14. ncbi Primary care in the United kingdom
    Azeem Majeed
    Department of Primary Care and Social Medicine, Imperial College Faculty of Medicine, London, United Kingdom
    J Ambul Care Manage 31:198-200. 2008
  15. ncbi MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine
    Albert L H J Aarnoudse
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Clin Pharmacol Ther 80:367-74. 2006
    ..We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein...
  16. ncbi Genetic and molecular factors in drug-induced liver injury: a review
    Ketevan Pachkoria
    Clinical Pharmacology Service, University Hospital Virgen de la Victoria, School of Medicine, Malaga, Spain
    Curr Drug Saf 2:97-112. 2007
    ..Knowledge regarding these operational mechanisms could provide further insight for the prospective identification of susceptible patients at risk of developing drug-induced hepatotoxicity...
  17. ncbi Common ATP-binding cassette B1 variants are associated with increased digoxin serum concentration
    Albert Jan L H J Aarnoudse
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
    Pharmacogenet Genomics 18:299-305. 2008
    ..The goal of this study was to establish ABCB1 genotype effect on digoxin blood concentrations in a large cohort of chronic digoxin users in a general Dutch European population...
  18. ncbi PAX4 gene variations predispose to ketosis-prone diabetes
    Franck Mauvais-Jarvis
    Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Mol Genet 13:3151-9. 2004
    ....