Research Topics
Species | Patrick H CorranSummaryAffiliation: London School of Hygiene and Tropical Medicine Country: UK Publications
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Detail Information
Publications
Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensityGeoffrey S Williams
Joint Malaria Programme, Kilimanjaro Christian Medical Centre, Moshi, Tanzania
Malar J 8:168. 2009..RDTs are now widely used for the diagnosis of malaria and estimation of parasite rates, and this method represents a further use for these devices in malaria control...- Comparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea BissauJudith Satoguina
Medical Research Council Laboratories, Fajara, PO Box 273 Banjul, The Gambia
Malar J 8:274. 2009..This study aims to provide parasite prevalence data from three sites in the Gambia and Guinea Bissau, respectively, and compares the usefulness of PCR, rapid diagnostic tests (RDT), serology and slide-microscopy for surveillance... - The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19)Jianguo Shi
Institute of Genetics, Queen s Medical Centre, University of Nottingham, NG7 2UH, UK
BMC Biotechnol 11:77. 2011..Although human serum immunoglobulin A (IgA) is the second most abundant class of antibody in the circulation, its contribution, if any, to protective responses against malaria is not clear... - Dried blood spots as a source of anti-malarial antibodies for epidemiological studiesPatrick H Corran
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
Malar J 7:195. 2008..Although recommendations for the storage and analysis of small molecule analytes in blood spots exist, there are no published systematic studies of the stability of antibodies under different storage conditions... - The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The GambiaPatrick H Corran
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
Infect Immun 72:6185-9. 2004..10) were significantly less likely to have malaria infections with densities of > or =1,000 parasites/microl than were individuals without such antibodies. This association persisted after correction for age and ethnic origin... - Fine specificity of serum antibodies to Plasmodium falciparum merozoite surface protein, PfMSP-1(19), predicts protection from malaria infection and high-density parasitemiaBrenda A Okech
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, National Institute for Medical Research, Mill Hill, London, United Kingdom
Infect Immun 72:1557-67. 2004..Future field studies, including the evaluation of PfMSP-1 vaccine trials, should include assays that explore antibody fine specificity as well as titer... - Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malariaJ Eric Tongren
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
Infect Immun 74:257-64. 2006..Our data also throw light on the consequences of class switch decisions on the gradual acquisition of antimalarial immunity... - Profiling the antibody immune response against blood stage malaria vaccine candidatesJulian C Gray
Faulty of Natural Sciences, Imperial College London, London, United Kingdom
Clin Chem 53:1244-53. 2007.... - Epitope-specific regulation of immunoglobulin class switching in mice immunized with malarial merozoite surface proteinsJon Eric Tongren
Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
Infect Immun 73:8119-29. 2005.... - Neutralization of malaria glycosylphosphatidylinositol in vitro by serum IgG from malaria-exposed individualsJ Brian de Souza
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom
Infect Immun 78:3920-9. 2010.... - Serological markers suggest heterogeneity of effectiveness of malaria control interventions on Bioko Island, equatorial GuineaJackie Cook
Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom
PLoS ONE 6:e25137. 2011..Bioko Island, Equatorial Guinea, has been subject to comprehensive malaria control interventions since 2004. This has resulted in substantial reductions in the parasite burden, although this drop has not been uniform across the island... - Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like moleculeFakhreldin M Omer
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom
J Exp Med 198:1817-27. 2003..Activation of LatTGF-beta represents a novel mechanism for direct modulation of the host response by malaria parasites...