Caroline A Whitehouse

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Brca1 expression is regulated by a bidirectional promoter that is shared by the Nbr1 gene in mouse
    Caroline Whitehouse
    Department of Medical and Molecular Genetics, Guy s, King s, and St Thomas School of Medicine, Guy s Hospital, 8th Floor, Guy s Tower, London SE1 9RT, UK
    Gene 326:87-96. 2004
  2. ncbi Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity
    Caroline A Whitehouse
    King s College London, Department of Medical and Molecular Genetics, London SE1 9RT, United Kindom
    Proc Natl Acad Sci U S A 107:12913-8. 2010
  3. ncbi Autophagic receptors Nbr1 and p62 coregulate skeletal remodeling
    Sarah Waters
    King s College London, Department of Medical and Molecular Genetics, London, England, UK
    Autophagy 6:981-3. 2010
  4. ncbi Characterisation of the FAM69 family of cysteine-rich endoplasmic reticulum proteins
    Anthea J Tennant-Eyles
    Department of Medical and Molecular Genetics, King s College London, London, UK
    Biochem Biophys Res Commun 406:471-7. 2011

Collaborators

Detail Information

Publications4

  1. ncbi Brca1 expression is regulated by a bidirectional promoter that is shared by the Nbr1 gene in mouse
    Caroline Whitehouse
    Department of Medical and Molecular Genetics, Guy s, King s, and St Thomas School of Medicine, Guy s Hospital, 8th Floor, Guy s Tower, London SE1 9RT, UK
    Gene 326:87-96. 2004
    ..The analysis of the murine and human syntenic region and its control has important implications for the regulation of human and murine BRCA1/NBR1 expression and the interpretation of animal models of disease...
  2. ncbi Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity
    Caroline A Whitehouse
    King s College London, Department of Medical and Molecular Genetics, London SE1 9RT, United Kindom
    Proc Natl Acad Sci U S A 107:12913-8. 2010
    ..Nbr1 truncation also leads to increased p62 protein expression. We show a role for Nbr1 in bone remodeling, where loss of function leads to perturbation of p62 levels and hyperactivation of p38 MAPK that favors osteoblastogenesis...
  3. ncbi Autophagic receptors Nbr1 and p62 coregulate skeletal remodeling
    Sarah Waters
    King s College London, Department of Medical and Molecular Genetics, London, England, UK
    Autophagy 6:981-3. 2010
    ..This is a molecular consequence of loss of autophagy receptor function via deletion of its C-terminal UBA domain, and/or modulation of the p38 MAPK cellular signaling pathway...
  4. ncbi Characterisation of the FAM69 family of cysteine-rich endoplasmic reticulum proteins
    Anthea J Tennant-Eyles
    Department of Medical and Molecular Genetics, King s College London, London, UK
    Biochem Biophys Res Commun 406:471-7. 2011
    ..FAM69 proteins are likely to play a fundamental and highly conserved role in the ER of most metazoan cells, with additional specialised roles in the vertebrate nervous system...