Research Topics
Genomes and GenesSpecies | Alan TaylorSummaryAffiliation: King's College London Country: UK Publications
| Collaborators
|
Detail Information
Publications
Meta-analysis of gene-environment interactions in developmental psychopathologyAlan Taylor
Social, Genetic and Developmental Psychiatry Centre, Box Number PO80, Institute of Psychiatry, King s College London, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
Dev Psychopathol 19:1029-37. 2007....
The consequences of selective participation on behavioral-genetic findings: evidence from simulated and real dataAlan Taylor
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, United Kingdom
Twin Res 7:485-504. 2004..Design and analysis methods that can be used to alleviate this potentially important biasing effect in behavioral-genetic studies are discussed in light of these findings...
A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorderAvshalom Caspi
Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, England
Arch Gen Psychiatry 65:203-10. 2008..Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous neurodevelopmental disorder that in some cases is accompanied by antisocial behavior...
Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interactionAvshalom Caspi
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
Biol Psychiatry 57:1117-27. 2005..The vast majority of cannabis users do not develop psychosis, however, prompting us to hypothesize that some people are genetically vulnerable to the deleterious effects of cannabis...
Revisiting the association between reading achievement and antisocial behavior: new evidence of an environmental explanation from a twin studyKali H Trzesniewski
Institute of Psychiatry, King s College London, UK
Child Dev 77:72-88. 2006..In contrast, the relation between reading achievement and attention deficit hyperactivity disorder was best explained by common genetic influences...
Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohortsJonathan Mill
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, England
Arch Gen Psychiatry 63:462-9. 2006..A principal aim of genetic research is to provide new information that can resolve such clinical heterogeneity and that can be incorporated into diagnostic practice...
School, neighborhood, and family factors are associated with children's bullying involvement: a nationally representative longitudinal studyLucy Bowes
Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, United Kingdom
J Am Acad Child Adolesc Psychiatry 48:545-53. 2009..To test whether school, neighborhood, and family factors are independently associated with children's involvement in bullying, over and above their own behaviors that may increase their risk for becoming involved in bullying...
Prenatal smoking and early childhood conduct problems: testing genetic and environmental explanations of the associationBarbara Maughan
Medical Research Council Social, Genetic and Developmental Psychiatry Centre, The Institute of Psychiatry, King s College London, London, England
Arch Gen Psychiatry 61:836-43. 2004..Though this statistical link may signal a causal association, commentators have urged caution in interpreting findings because of the likelihood of confounding...
Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolismAvshalom Caspi
Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London SE5 8AF, England
Proc Natl Acad Sci U S A 104:18860-5. 2007..The finding shows that environmental exposures can be used to uncover novel candidate genes in complex phenotypes. It also shows that genes may work via the environment to shape the IQ, helping to close the nature versus nurture debate...
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT geneAvshalom Caspi
Medical Research Council Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, PO80 De Crespigny Park, London, SE5 8AF, UK
Science 301:386-9. 2003..This epidemiological study thus provides evidence of a gene-by-environment interaction, in which an individual's response to environmental insults is moderated by his or her genetic makeup...
Psychometric evaluation of 5- and 7-year-old children's self-reports of conduct problemsLouise Arseneault
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, UK
J Abnorm Child Psychol 33:537-50. 2005..For research and clinical purposes, young children's self-reports can be viewed as a valuable complement to adults' ratings and observational measures of children's behavior problems...
Strong genetic effects on cross-situational antisocial behaviour among 5-year-old children according to mothers, teachers, examiner-observers, and twins' self-reportsLouise Arseneault
Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 44:832-48. 2003..Genetic etiology is unknown because most research with young children focuses on environmental risk factors, and the few existing studies of young twins used only mothers' reports of behaviour, which may be biased...
Being bullied as an environmentally mediated contributing factor to children's internalizing problems: a study of twins discordant for victimizationLouise Arseneault
Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Campus Box P080, De Crespigny Park, London SE5 8AF, England
Arch Pediatr Adolesc Med 162:145-50. 2008..To test whether the experience of being bullied has an environmentally mediated effect on internalizing symptoms in young children...
Validity of DSM-IV conduct disorder in 41/2-5-year-old children: a longitudinal epidemiological studyJulia Kim-Cohen
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London SE5 8AF, UK
Am J Psychiatry 162:1108-17. 2005..This longitudinal study of a nonreferred, population-based sample tested the concurrent, convergent, and predictive validity of DSM-IV conduct disorder in children 4(1/2)-5 years of age...
Maternal expressed emotion predicts children's antisocial behavior problems: using monozygotic-twin differences to identify environmental effects on behavioral developmentAvshalom Caspi
Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King's College London, London, England
Dev Psychol 40:149-61. 2004..The results suggest that maternal emotional attitudes toward children may play a causal role in the development of antisocial behavior and illustrate how genetically informative research can inform tests of socialization hypotheses...
Role of genotype in the cycle of violence in maltreated childrenAvshalom Caspi
Medical Research Council Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College, London SE5 8AF, UK
Science 297:851-4. 2002..These findings may partly explain why not all victims of maltreatment grow up to victimize others, and they provide epidemiological evidence that genotypes can moderate children's sensitivity to environmental insults...
Genetic and environmental processes in young children's resilience and vulnerability to socioeconomic deprivationJulia Kim-Cohen
Social Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny, United Kingdom
Child Dev 75:651-68. 2004..Findings add new information by demonstrating that resilience is partly heritable and that protective processes operate through both genetic and environmental effects...
Life with (or without) father: the benefits of living with two biological parents depend on the father's antisocial behaviorSara R Jaffee
Institute of Psychiatry, King s College, London, UK
Child Dev 74:109-26. 2003..Marriage may not be the answer to the problems faced by some children living in single-parent families unless their fathers can become reliable sources of emotional and economic support...
The targets of violence committed by young offenders with alcohol dependence, marijuana dependence and schizophrenia-spectrum disorders: findings from a birth cohortLouise Arseneault
Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, University of London, London, UK
Crim Behav Ment Health 12:155-68. 2002..Families, schoolteachers and primary care physicians have an important potentially preventive role in early identification and treatment of the disorders...
Maternal depression and children's antisocial behavior: nature and nurture effectsJulia Kim-Cohen
Institute of Psychiatry, King s College London, London, England
Arch Gen Psychiatry 62:173-81. 2005....
What effect does classroom separation have on twins' behavior, progress at school, and reading abilities?Lucy A Tully
Institute of Psychiatry, King's College London, UK
Twin Res 7:115-24. 2004..No group differences emerged for externalizing problems, ADHD or prosocial behaviors. The implications of the findings for parents and teachers of twins, and for school practices about separating twins, are discussed...
Genetic and environmental influences on victims, bullies and bully-victims in childhoodHarriet A Ball
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 49:104-12. 2008..Understanding the origins of these groups is important since they have elevated emotional and behavioural problems, especially the bully-victims. No research has examined the genetic and environmental influences on these social roles...
Childhood maltreatment predicts adult inflammation in a life-course studyAndrea Danese
Medical Research Council Social, Genetic, and Developmental Psychiatry Centre and Department of Psychological Medicine, Institute of Psychiatry, King s College London, London SE5 8AF, United Kingdom
Proc Natl Acad Sci U S A 104:1319-24. 2007..Inflammation may be an important developmental mediator linking adverse experiences in early life to poor adult health...
Influence of adult domestic violence on children's internalizing and externalizing problems: an environmentally informative twin studySara R Jaffee
Institute of Psychiatry, King s College London, England
J Am Acad Child Adolesc Psychiatry 41:1095-103. 2002....
Precursors and correlates of criminal behaviour in womenJulie Messer
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
Crim Behav Ment Health 14:82-107. 2004..The precursors and correlates of criminal behaviour in women were examined in this longitudinal study of women in their late thirties...
Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohortMary Cannon
Division of Psychological Medicine, Institute of Psychiatry, London, England
Arch Gen Psychiatry 59:449-56. 2002..CONCLUSIONS: The results provide evidence for an early-childhood, persistent, pan-developmental impairment that is specifically associated with schizophreniform disorder and that predicts psychotic symptoms in childhood and adulthood...
'I'm gonna beat you!' SNap!: an observational paradigm for assessing young children's disruptive behaviour in competitive playClaire Hughes
Centre for Family Research, University of Cambridge, UK
J Child Psychol Psychiatry 43:507-16. 2002..Recent work suggests that this paradigm is useful for assessing disruptive behaviour in young children (Hughes, Cutting, & Dunn, 2001)...
Usefulness of the Threatening Medical Situations Inventory in individuals considering genetic testing for cancer riskClaire E Wakefield
Department of Psychology, Macquarie University, NSW, Australia
Patient Educ Couns 69:29-38. 2007..To assess the psychometric properties of the Threatening Medical Situations Inventory (TMSI) in a community sample (Study 1), and to examine its usefulness in individuals with a strong family history of cancer (Study 2)...
Individual, family, and neighborhood factors distinguish resilient from non-resilient maltreated children: a cumulative stressors modelSara R Jaffee
Department of Psychology, University of Pennsylvania, 3720 Walnut Street, Philadelphia, PA 19104, USA
Child Abuse Negl 31:231-53. 2007..characteristics distinguish resilient from non-resilient maltreated children? Do children's individual strengths promote resilience even when children are exposed to multiple family and neighborhood stressors (cumulative stressors model)?..
Genetic influences on the overlap between low IQ and antisocial behavior in young childrenKarestan C Koenen
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
J Abnorm Psychol 115:787-97. 2006..Genetic influences common to both phenotypes explained 100% of the low IQ-antisocial behavior relation in boys. Findings suggest that specific candidate genes and neurobiological processes should be tested in relation to both phenotypes...
Physical maltreatment victim to antisocial child: evidence of an environmentally mediated processSara R Jaffee
University of Pennsylvania, Department of Psychology, Philadelphia, PA 19104, USA
J Abnorm Psychol 113:44-55. 2004..The findings support the hypothesis that physical maltreatment plays a causal role in the development of children's antisocial behavior and that preventing maltreatment can prevent its violent sequelae...
Domestic violence is associated with environmental suppression of IQ in young childrenKarestan C Koenen
National Child Traumatic Stress Network, Department of Child and Adolescent Psychiatry, Boston University Medical Center, MA 02118, USA
Dev Psychopathol 15:297-311. 2003....
The limits of child effects: evidence for genetically mediated child effects on corporal punishment but not on physical maltreatmentSara R Jaffee
Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA
Dev Psychol 40:1047-58. 2004..The authors conclude that risk factors for maltreatment are less likely to reside within the child and more likely to reside in characteristics that differ between families...
Origins of individual differences in theory of mind: from nature to nurture?Claire Hughes
Centre for Family Research, University of Cambridge, UK
Child Dev 76:356-70. 2005..Possible underlying proximal mechanisms are discussed, including maternal speech and mind-mindedness, sibling interactions, and peer influences...
The neuropsychological and language profile of children with benign rolandic epilepsyEllen Northcott
School of Women's and Children's Health, University of NSW, Australia
Epilepsia 46:924-30. 2005..Difficulties in phonologic awareness affect literacy, and memory problems affect academic performance...
Nature X nurture: genetic vulnerabilities interact with physical maltreatment to promote conduct problemsSara R Jaffee
Department of Psychology, University of Pennsylvania, 3720 Walnut Street, Philadelphia, PA 19104, USA
Dev Psychopathol 17:67-84. 2005..Certain genotypes may promote resistance to trauma. Physically maltreated children whose first-degree relatives engage in antisocial behavior warrant priority for therapeutic intervention...
Association between children's experience of socioeconomic disadvantage and adult health: a life-course studyRichie Poulton
Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand
Lancet 360:1640-5. 2002..We aimed to test the hypothesis that children's experience of socioeconomic disadvantage is associated with a wide range of health risk factors and outcomes in adult life...
Odds of demonstrating auditory processing abnormality in the average older adult: the Blue Mountains Hearing StudyMaryanne Golding
National Acoustic Laboratories, Chatswood, New South Wales, Australia
Ear Hear 27:129-38. 2006....
Measuring social structure: a comparison of eight dominance indicesKaren L Bayly
Animal Behaviour Laboratory, Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, Australia
Behav Processes 73:1-12. 2006..Taken together, our results read as a cautionary tale. We suggest that selection of a dominance index requires careful consideration both of algorithm properties and of the factors affecting social status in the system of interest...
[Socioeconomic and educational inequities as independent predictors for mortality in a developing country: A cohort study in San Francisco, Chile]Elard Koch
Escuela de Salud Publica, Facultad de Medicina, Universidad de Chile, Santiago, Chile
Rev Med Chil 135:1370-9. 2007..The socioeconomic position (SEP) and educational level of individuals have an inverse correlation with mortality in developed societies...
Longitudinal assessment of neuropsychologic and language function in children with benign rolandic epilepsyEllen Northcott
School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia
J Child Neurol 21:518-22. 2006..It is important to recognize cognitive difficulties in children with benign rolandic epilepsy. Some difficulties can resolve; however, continued monitoring, particularly in areas of visual memory and phonologic awareness, is required...
