E Simonoff

..To determine whether the nature and correlates of attention-deficit/hyperactivity disorder (ADHD) symptoms are different in subjects with mild intellectual disability (ID) compared to subjects with average ability...

..Recent reports have suggested that the prevalence of autism and related spectrum disorders (ASDs) is substantially higher than previously recognised. We sought to quantify prevalence of ASDs in children in South Thames, UK...

..To examine the properties of the Social Communication Questionnaire (SCQ) in a population cohort of children with autism spectrum disorders (ASDs) and in the general population...

..This study takes an individual differences approach to determine the degree of phenotypic and aetiological overlap between autistic traits and ADHD behaviours in the general population...

..The current study estimates the prevalence of low IQ in the mental retardation range (intellectual disability) in a population sample and examines the factors that relate to educational identification...

..Antisocial behaviour in adult life has its roots in childhood...

..Where convincing evidence does not exist, researchers should explore alternative models and determine their power to discriminate between these models...

..We identify the rates and type of psychiatric comorbidity associated with ASDs and explore the associations with variables identified as risk factors for child psychiatric disorders...

..However, there are few data from epidemiological studies...

..Enhanced knowledge of the cognitive phenotype may contribute to our understanding of the complex links between genes, brain and behaviour, as well as inform approaches to remediation...

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..Current research, however, has consistently highlighted the importance of gene-environment interplay in antisocial behavior...

..Because the genetic and environmental origins of V and P delays in infancy differ, they are better considered separately rather than combined into a composite measure of general cognitive delay...

..An empirical study showed that a recognition of the role of methodological factors was helpful to understand part of the differences between assessment instruments, raters, and data analysis techniques that were found in the real data...

..These data lend support for intervention in ending ESES by 36 months using multiple subpial transection (MST) if steroids are ineffective or cause unacceptable side effects...

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..Although these mice have no obvious behavioural phenotype, the results presented here suggest that humans with the equivalent mutation display a neurobehavioural phenotype...

..45, P = 0.06, OR = 1.15), however we find significant evidence of heterogeneity between the combined dataset (chi(2) = 22.64, df = 8, P = 0.004)...

..However parents often lack emotional and practical support in coping with their children's complex needs. Agencies need to improve communication and joint working to provide effective services for these families...

..Exposure to childhood adversity may explain why only a minority of combatants exposed to trauma develop psychological problems...

..We present further evidence of these associations and address the underlying mechanisms. We also examine the genetic contribution to unintentional injury...

..To determine the impact of pregnancy on eating disorders (ED) symptoms using data from a large prospective, community-based cohort study...

..Contrast effects acting in the same direction at different ages contributed to the observed continuity:longitudinal correlations were greater for dizygotic than monozygotic twins...

..Low birth weight, prematurity and higher miscarriage rates have previously been reported in women with eating disorders...

..Staff who felt more effective felt less negative towards this group of patients (B=-0.21, p=0.03). Forty-two per cent of the participants wanted further training in DSH amongst adolescents...

..CONCLUSIONS: The pattern of comorbidity suggests overlap between bulimia symptoms and those of internalizing disorders. Substantial genetic variance (44%) was evident in the most conservative model...

..Screening instruments for autistic-spectrum disorders have not been compared in the same sample...

..The findings expand the range of disadvantages associated with early stunting, which affects 151 million children <5 y old in developing countries...

..To determine whether dietary supplementation or psychosocial stimulation given to growth retarded (stunted) children age 9-24 months has long term benefits for their psychosocial functioning in late adolescence...